MPD: Project measures / variables set: Schoonjans1 GCA

Project measures / variables set: Schoonjans1 GCA_liver

ID, description, units	MPD:112822 GCA_liver bile acid glycocholic acid amount in liver, at 29 wks [ng/mL] high-fat diet study
Measures	• CD • HFD
Data set, strains	Schoonjans1 BXD w/par 36 strains sex: m age: 29wks
Procedure	biomarker quantification
Comparison	control group vs. treated group
Ontology mappings	VT:0010918 liver bile acid amount MA:0000358 liver

Values Means Δ Means Z-scores

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Schoonjans1 - bile acid glycocholic acid amount in liver, at 29 wks

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	0.0022	0.0022	2.7831	0.0964
strain	35	0.1927	0.0055	7.1142	< 0.0001
group:strain	35	0.1403	0.004	5.1799	< 0.0001
Residuals	275	0.2128	0.0008

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Schoonjans1	112822	biomarker quantification	high-fat diet	bile acid glycocholic acid amount in liver, at 29 wks [ng/mL] CD GCA_liver_CD	BXD w/par	36	m	29wks
Schoonjans1	112823	biomarker quantification	high-fat diet	bile acid glycocholic acid amount in liver, at 29 wks [ng/mL] HFD GCA_liver_HFD	BXD w/par	36	m	29wks