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Project measure / variable:   CSNA02   EtOH_licks_d2

ID, description, units MPD:62227   EtOH_licks_d2   licks on ethanol bottle as a percentage of total licks 'drinking in the dark'   [%]  day 2  
ethanol study
Data set, strains CSNA02   inbred   18 strains     sex: both     age: 16-39wks
Procedure bottle choice test
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  STRAIN COMPARISON PLOT
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CSNA02 - licks on ethanol bottle as a percentage of total licks 'drinking in the dark' day 2



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested18 strains18 strains
Mean of the strain means21.628   % 17.761   %
Median of the strain means18.965   % 12.195   %
SD of the strain means± 14.453 ± 15.427
Coefficient of variation (CV)0.6682 0.8686
Min–max range of strain means4.66   –   61.67   % 0.45   –   51.81   %
Mean sample size per strain5.4   mice 5.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 547.1686 547.1686 1.3993 0.2386
strain 16 36322.5029 2270.1564 5.8057 < 0.0001
sex:strain 16 7154.7988 447.1749 1.1436 0.3197
Residuals 162 63345.4697 391.0214


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 20.214 27.386   8 9.6826 1.3548 0.85, 86.34 -0.1
129S1/SvImJ m 10.765 15.351   6 6.2671 1.426 0.84, 41.82 -0.45
A/J f 18.408 19.286   9 6.4286 1.0477 3.36, 62.38 -0.22
A/J m 21.203 23.468   9 7.8226 1.1068 4.43, 73.8 0.22
C57BL/6J f 24.706 20.12   8 7.1133 0.8143 4.5, 53.48 0.21
C57BL/6J m 40.214 27.681   7 10.462 0.6883 3.05, 93.28 1.46
CAST/EiJ f 25.041 22.118   8 7.82 0.8833 10.04, 77.71 0.24
CAST/EiJ m 9.0 3.2582   8 1.1519 0.362 4.72, 14.04 -0.57
CC002/UncJ f 14.95 17.195   3 9.9277 1.1502 2.89, 34.64 -0.46
CC002/UncJ m 4.9533 2.1016   3 1.2133 0.4243 3.73, 7.38 -0.83
CC004/TauUncJ f 15.572 17.471   5 7.8132 1.1219 4.42, 45.55 -0.42
CC004/TauUncJ m 8.8044 8.2349   9 2.745 0.9353 1.04, 28.1 -0.58
CC006/TauUncJ f 35.183 25.195   3 14.546 0.7161 6.56, 54.0 0.94
CC006/TauUncJ m 17.877 21.209   3 12.245 1.1864 4.87, 42.35 0.01
CC011/UncJ f 37.68 33.432   2   23.64 0.8873 14.04, 61.32 1.11
CC011/UncJ m 27.86 33.658   2   23.8 1.2081 4.06, 51.66 0.65
CC012/GeniUncJ f 19.523 13.344   3 7.7042 0.6835 5.36, 31.86 -0.15
CC012/GeniUncJ m 20.223 4.3682   3 2.522 0.216 15.2, 23.13 0.16
CC025/GeniUncJ f 11.65 0.0   1   0.0 0.0 11.65, 11.65 -0.69
CC025/GeniUncJ m 0.45 0.0   1   0.0 0.0 0.45, 0.45 -1.12
CC028/GeniUncJ f 6.8533 5.9922   3 3.4596 0.8744 2.15, 13.6 -1.02
CC028/GeniUncJ m 2.9633 0.89846   3 0.51873 0.3032 2.41, 4.0 -0.96
CC032/GeniUncJ f 36.48 55.13   3 31.828 1.5112 1.12, 100.0 1.03
CC032/GeniUncJ m 9.44 11.37   3 6.5645 1.2044 1.67, 22.49 -0.54
CC041/TauUncJ f 4.66 3.3506   9 1.1169 0.719 0.86, 11.52 -1.17
CC041/TauUncJ m 7.0733 10.644   9 3.5481 1.5048 1.04, 34.8 -0.69
CC061/GeniUncJ f 8.335 1.7183   2   1.215 0.2062 7.12, 9.55 -0.92
CC061/GeniUncJ m 50.42 43.373   3 25.041 0.8603 2.1, 85.99 2.12
NOD/ShiLtJ f 5.4917 8.9275   6 3.6446 1.6256 0.18, 23.44 -1.12
NOD/ShiLtJ m 7.7383 14.255   6 5.8197 1.8422 -0.65
NZO/HlLtJ f 13.587 12.014   9 4.0046 0.8842 3.33, 35.77 -0.56
NZO/HlLtJ m 15.276 9.7166   9 3.2389 0.6361 3.28, 29.27 -0.16
PWK/PhJ f 61.67 20.977   8 7.4163 0.3401 25.23, 87.35 2.77
PWK/PhJ m 51.81 25.282   9 8.4274 0.4879 7.73, 82.27 2.21
WSB/EiJ f 29.306 31.791   7 12.016 1.0848 0.7, 90.82 0.53
WSB/EiJ m 13.626 19.546   8 6.9107 1.4345 2.84, 61.39 -0.27


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 20.2137 6.9913 34.0195 6.408
129S1/SvImJ m 10.765 8.0728 26.7065 -5.1765
A/J f 18.4078 6.5914 31.424 5.3916
A/J m 21.2033 6.5914 34.2195 8.1872
C57BL/6J f 24.7062 6.9913 38.512 10.9005
C57BL/6J m 40.2143 7.474 54.9732 25.4553
CAST/EiJ f 25.0412 6.9913 38.847 11.2355
CAST/EiJ m 9.0 6.9913 22.8057 -4.8057
CC002/UncJ f 14.95 11.4167 37.4947 -7.5947
CC002/UncJ m 4.9533 11.4167 27.498 -17.5914
CC004/TauUncJ f 15.572 8.8433 33.035 -1.891
CC004/TauUncJ m 8.8044 6.5914 21.8206 -4.2117
CC006/TauUncJ f 35.1833 11.4167 57.728 12.6386
CC006/TauUncJ m 17.8767 11.4167 40.4214 -4.668
CC011/UncJ f 37.68 13.9825 65.2915 10.0685
CC011/UncJ m 27.86 13.9825 55.4715 0.2485
CC012/GeniUncJ f 19.5233 11.4167 42.068 -3.0214
CC012/GeniUncJ m 20.2233 11.4167 42.768 -2.3214
CC028/GeniUncJ f 6.8533 11.4167 29.398 -15.6914
CC028/GeniUncJ m 2.9633 11.4167 25.508 -19.5814
CC032/GeniUncJ f 36.48 11.4167 59.0247 13.9353
CC032/GeniUncJ m 9.44 11.4167 31.9847 -13.1047
CC041/TauUncJ f 4.66 6.5914 17.6762 -8.3562
CC041/TauUncJ m 7.0733 6.5914 20.0895 -5.9428
CC061/GeniUncJ f 8.335 13.9825 35.9465 -19.2765
CC061/GeniUncJ m 50.4167 11.4167 72.9614 27.872
NOD/ShiLtJ f 5.4917 8.0728 21.4332 -10.4498
NOD/ShiLtJ m 7.7383 8.0728 23.6798 -8.2032
NZO/HlLtJ f 13.5867 6.5914 26.6028 0.5705
NZO/HlLtJ m 15.2756 6.5914 28.2917 2.2594
PWK/PhJ f 61.6712 6.9913 75.477 47.8655
PWK/PhJ m 51.8144 6.5914 64.8306 38.7983
WSB/EiJ f 29.3057 7.474 44.0647 14.5468
WSB/EiJ m 13.6262 6.9913 27.432 -0.1795


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 15.4894 5.3397 26.0337 4.9451
A/J both 19.8056 4.6608 29.0094 10.6017
C57BL/6J both 32.4603 5.1171 42.565 22.3555
CAST/EiJ both 17.0206 4.9436 26.7828 7.2585
CC002/UncJ both 9.9517 8.0728 25.8932 -5.9898
CC004/TauUncJ both 12.1882 5.5148 23.0783 1.2981
CC006/TauUncJ both 26.53 8.0728 42.4715 10.5885
CC011/UncJ both 32.77 9.8871 52.2943 13.2457
CC012/GeniUncJ both 19.8733 8.0728 35.8148 3.9318
CC028/GeniUncJ both 4.9083 8.0728 20.8498 -11.0332
CC032/GeniUncJ both 22.96 8.0728 38.9015 7.0185
CC041/TauUncJ both 5.8667 4.6608 15.0705 -3.3372
CC061/GeniUncJ both 29.3758 9.0257 47.199 11.5527
NOD/ShiLtJ both 6.615 5.7083 17.8873 -4.6573
NZO/HlLtJ both 14.4311 4.6608 23.6349 5.2273
PWK/PhJ both 56.7428 4.8043 66.2299 47.2558
WSB/EiJ both 21.466 5.1171 31.5708 11.3612




  GWAS USING LINEAR MIXED MODELS