Project measure / variable:   CSNA02   EtOH_licks_d1

ID, description, units MPD:62226   EtOH_licks_d1   licks on ethanol bottle as a percentage of total licks 'drinking in the dark'   [%]  day 1  
ethanol study
Data set, strains CSNA02   inbred   18 strains     sex: both     age: 16-39wks
Procedure bottle choice test
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  STRAIN COMPARISON PLOT
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CSNA02 - licks on ethanol bottle as a percentage of total licks 'drinking in the dark' day 1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested18 strains18 strains
Mean of the strain means26.608   % 25.658   %
Median of the strain means26.051   % 20.956   %
SD of the strain means± 14.523 ± 17.868
Coefficient of variation (CV)0.5458 0.6964
Min–max range of strain means3.115   –   53.08   % 1.75   –   66.4   %
Mean sample size per strain5.3   mice 5.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 9.5412 9.5412 0.0321 0.858
strain 16 36652.7478 2290.7967 7.7058 < 0.0001
sex:strain 16 9993.9238 624.6202 2.1011 0.0106
Residuals 160 47564.9428 297.2809


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 13.146 11.96   8 4.2285 0.9098 0.38, 38.9 -0.93
129S1/SvImJ m 30.987 21.717   6 8.866 0.7009 0.33, 63.61 0.3
A/J f 25.924 23.886   9 7.9619 0.9214 5.13, 76.4 -0.05
A/J m 44.933 22.36   9 7.4532 0.4976 16.96, 76.96 1.08
C57BL/6J f 41.69 19.606   8 6.9317 0.4703 7.81, 70.1 1.04
C57BL/6J m 66.4 10.62   7 4.0141 0.16 51.79, 80.85 2.28
CAST/EiJ f 26.179 14.879   8 5.2606 0.5684 12.05, 55.07 -0.03
CAST/EiJ m 15.284 2.9567   8 1.0454 0.1935 10.76, 19.3 -0.58
CC002/UncJ f 12.38 11.364   3 6.5612 0.918 5.6, 25.5 -0.98
CC002/UncJ m 7.1233 2.7168   3 1.5686 0.3814 5.14, 10.22 -1.04
CC004/TauUncJ f 25.226 16.457   5 7.3598 0.6524 14.0, 54.21 -0.1
CC004/TauUncJ m 15.012 6.7097   9 2.2366 0.447 3.66, 25.87 -0.6
CC006/TauUncJ f 51.66 8.503   3 4.9092 0.1646 42.19, 58.64 1.73
CC006/TauUncJ m 47.91 18.587   3 10.731 0.388 28.07, 64.92 1.25
CC011/UncJ f 37.57 19.559   2   13.83 0.5206 23.74, 51.4 0.75
CC011/UncJ m 19.105 14.503   2   10.255 0.7591 8.85, 29.36 -0.37
CC012/GeniUncJ f 24.68 19.078   3 11.015 0.773 10.5, 46.37 -0.13
CC012/GeniUncJ m 38.21 16.639   3 9.6067 0.4355 19.39, 50.97 0.7
CC025/GeniUncJ f 27.43 0.0   1   0.0 0.0 27.43, 27.43 0.06
CC025/GeniUncJ m 1.75 0.0   1   0.0 0.0 1.75, 1.75 -1.34
CC028/GeniUncJ f 6.3133 6.5696   3 3.793 1.0406 2.2, 13.89 -1.4
CC028/GeniUncJ m 4.0333 0.32747   3 0.18906 0.0812 3.77, 4.4 -1.21
CC032/GeniUncJ f 19.925 8.7045   2   6.155 0.4369 13.77, 26.08 -0.46
CC032/GeniUncJ m 14.233 9.4708   3 5.468 0.6654 3.31, 20.15 -0.64
CC041/TauUncJ f 8.2867 5.0039   9 1.668 0.6039 3.28, 19.14 -1.26
CC041/TauUncJ m 6.6089 2.9108   9 0.97027 0.4404 3.09, 11.49 -1.07
CC061/GeniUncJ f 3.115 1.9304   2   1.365 0.6197 1.75, 4.48 -1.62
CC061/GeniUncJ m 38.807 36.632   3 21.149 0.944 2.59, 75.84 0.74
NOD/ShiLtJ f 33.087 34.102   6 13.922 1.0307 0.96, 93.1 0.45
NOD/ShiLtJ m 19.213 16.998   6 6.9395 0.8847 0.22, 39.27 -0.36
NZO/HlLtJ f 36.034 13.782   9 4.5941 0.3825 13.88, 53.48 0.65
NZO/HlLtJ m 22.698 14.299   9 4.7664 0.63 7.9, 44.35 -0.17
PWK/PhJ f 53.08 23.263   8 8.2248 0.4383 0.59, 72.98 1.82
PWK/PhJ m 44.399 16.928   8 5.985 0.3813 17.12, 66.96 1.05
WSB/EiJ f 33.227 23.408   7 8.8472 0.7045 12.51, 77.7 0.46
WSB/EiJ m 25.14 22.177   8 7.8408 0.8821 10.31, 74.85 -0.03


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 13.1463 6.0959 25.1851 1.1074
129S1/SvImJ m 30.9867 7.0389 44.8879 17.0854
A/J f 25.9244 5.7473 37.2748 14.5741
A/J m 44.9333 5.7473 56.2836 33.583
C57BL/6J f 41.69 6.0959 53.7288 29.6512
C57BL/6J m 66.3957 6.5168 79.2658 53.5257
CAST/EiJ f 26.1788 6.0959 38.2176 14.1399
CAST/EiJ m 15.2838 6.0959 27.3226 3.2449
CC002/UncJ f 12.38 9.9546 32.0393 -7.2793
CC002/UncJ m 7.1233 9.9546 26.7826 -12.536
CC004/TauUncJ f 25.226 7.7108 40.454 9.998
CC004/TauUncJ m 15.0122 5.7473 26.3625 3.6619
CC006/TauUncJ f 51.66 9.9546 71.3193 32.0007
CC006/TauUncJ m 47.91 9.9546 67.5693 28.2507
CC011/UncJ f 37.57 12.1918 61.6476 13.4924
CC011/UncJ m 19.105 12.1918 43.1826 -4.9726
CC012/GeniUncJ f 24.68 9.9546 44.3393 5.0207
CC012/GeniUncJ m 38.21 9.9546 57.8693 18.5507
CC028/GeniUncJ f 6.3133 9.9546 25.9726 -13.346
CC028/GeniUncJ m 4.0333 9.9546 23.6926 -15.626
CC032/GeniUncJ f 19.925 12.1918 44.0026 -4.1526
CC032/GeniUncJ m 14.2333 9.9546 33.8926 -5.426
CC041/TauUncJ f 8.2867 5.7473 19.637 -3.0636
CC041/TauUncJ m 6.6089 5.7473 17.9592 -4.7414
CC061/GeniUncJ f 3.115 12.1918 27.1926 -20.9626
CC061/GeniUncJ m 38.8067 9.9546 58.466 19.1474
NOD/ShiLtJ f 33.0867 7.0389 46.9879 19.1854
NOD/ShiLtJ m 19.2133 7.0389 33.1146 5.3121
NZO/HlLtJ f 36.0344 5.7473 47.3848 24.6841
NZO/HlLtJ m 22.6978 5.7473 34.0481 11.3475
PWK/PhJ f 53.0813 6.0959 65.1201 41.0424
PWK/PhJ m 44.3988 6.0959 56.4376 32.3599
WSB/EiJ f 33.2271 6.5168 46.0972 20.3571
WSB/EiJ m 25.14 6.0959 37.1788 13.1012


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 22.0665 4.6558 31.2613 12.8717
A/J both 35.4289 4.0639 43.4548 27.403
C57BL/6J both 54.0429 4.4617 62.8544 45.2313
CAST/EiJ both 20.7313 4.3105 29.244 12.2185
CC002/UncJ both 9.7517 7.0389 23.6529 -4.1496
CC004/TauUncJ both 20.1191 4.8085 29.6155 10.6228
CC006/TauUncJ both 49.785 7.0389 63.6862 35.8838
CC011/UncJ both 28.3375 8.6209 45.363 11.312
CC012/GeniUncJ both 31.445 7.0389 45.3462 17.5438
CC028/GeniUncJ both 5.1733 7.0389 19.0746 -8.7279
CC032/GeniUncJ both 17.0792 7.8698 32.6212 1.5371
CC041/TauUncJ both 7.4478 4.0639 15.4737 -0.5781
CC061/GeniUncJ both 20.9608 7.8698 36.5029 5.4188
NOD/ShiLtJ both 26.15 4.9773 35.9797 16.3203
NZO/HlLtJ both 29.3661 4.0639 37.392 21.3402
PWK/PhJ both 48.74 4.3105 57.2527 40.2273
WSB/EiJ both 29.1836 4.4617 37.9951 20.3721




  GWAS USING LINEAR MIXED MODELS