Project measure / variable:   Schughart3   day_survivalA

ID, description, units MPD:57181   day_survivalA   survival, post-infection   [d]  10 FFU group  
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   8 strains     sex: both     age: 7-13wks
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  STRAIN COMPARISON PLOT
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Schughart3 - survival, post-infection 10 FFU group



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means10.4   d 11.3   d
Median of the strain means10.4   d 11.8   d
SD of the strain means± 2.59 ± 2.57
Coefficient of variation (CV)0.249 0.228
Min–max range of strain means7.10   –   14.0   d 7.70   –   14.0   d
Mean sample size per strain10.5   mice 10.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 45.5651 45.5651 17.5567 < 0.0001
strain 7 927.3117 132.4731 51.0431 < 0.0001
sex:strain 7 26.7714 3.8245 1.4736 0.1807
Residuals 150 389.2975 2.5953


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 10.4 2.6   9 0.868 0.249 8.0, 14.0 -0.01
129S1/SvImJ m 11.8 2.23   11 0.672 0.189 9.0, 14.0 0.2
A/J f 7.1 0.738   10 0.233 0.104 6.0, 8.0 -1.28
A/J m 7.7 0.483   10 0.153 0.0627 7.0, 8.0 -1.39
C57BL/6J f 10.3 3.04   11 0.915 0.296 7.0, 14.0 -0.05
C57BL/6J m 11.7 2.5   10 0.79 0.213 8.0, 14.0 0.16
CAST/EiJ f 8.1 1.29   10 0.407 0.159 6.0, 10.0 -0.9
CAST/EiJ m 8.14 0.9   7 0.34 0.11 7.0, 9.0 -1.22
NOD/ShiLtJ f 11.2 2.74   10 0.867 0.245 7.0, 14.0 0.3
NOD/ShiLtJ m 13.5 1.25   15 0.322 0.0921 10.0, 14.0 0.86
NZO/HlLtJ f 14.0 0.0   10 0.0 0.0 14.0, 14.0 1.38
NZO/HlLtJ m 14.0 0.0   9 0.0 0.0 14.0, 14.0 1.06
PWK/PhJ f 14.0 0.0   12 0.0 0.0 14.0, 14.0 1.38
PWK/PhJ m 14.0 0.0   10 0.0 0.0 14.0, 14.0 1.06
WSB/EiJ f 8.33 0.778   12 0.225 0.0934 7.0, 10.0 -0.81
WSB/EiJ m 9.4 1.26   10 0.4 0.135 8.0, 12.0 -0.73


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 10.4444 0.537 11.5055 9.3834
129S1/SvImJ m 11.8182 0.4857 12.7779 10.8584
A/J f 7.1 0.5094 8.1066 6.0934
A/J m 7.7 0.5094 8.7066 6.6934
C57BL/6J f 10.2727 0.4857 11.2325 9.313
C57BL/6J m 11.7 0.5094 12.7066 10.6934
CAST/EiJ f 8.1 0.5094 9.1066 7.0934
CAST/EiJ m 8.1429 0.6089 9.346 6.9397
NOD/ShiLtJ f 11.2 0.5094 12.2066 10.1934
NOD/ShiLtJ m 13.5333 0.416 14.3552 12.7114
NZO/HlLtJ f 14.0 0.5094 15.0066 12.9934
NZO/HlLtJ m 14.0 0.537 15.0611 12.9389
PWK/PhJ f 14.0 0.4651 14.9189 13.0811
PWK/PhJ m 14.0 0.5094 15.0066 12.9934
WSB/EiJ f 8.3333 0.4651 9.2522 7.4144
WSB/EiJ m 9.4 0.5094 10.4066 8.3934


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 11.1313 0.362 11.8467 10.4159
A/J both 7.4 0.3602 8.1118 6.6882
C57BL/6J both 10.9864 0.3519 11.6818 10.2909
CAST/EiJ both 8.1214 0.397 8.9058 7.3371
NOD/ShiLtJ both 12.3667 0.3288 13.0164 11.7169
NZO/HlLtJ both 14.0 0.3701 14.7313 13.2687
PWK/PhJ both 14.0 0.3449 14.6815 13.3185
WSB/EiJ both 8.8667 0.3449 9.5481 8.1852




  GWAS USING LINEAR MIXED MODELS