Project measure / variable:   Schughart3   pctbwA_d9

ID, description, units MPD:57119   pctbwA_d9   body weight as percent of baseline, 10 FFU group   [%]  post-infection day 9  
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   7 strains     sex: both     age: 7-13wks
Procedure body weight
Ontology mappings

  STRAIN COMPARISON PLOT
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Schughart3 - body weight as percent of baseline, 10 FFU group post-infection day 9



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains6 strains
Mean of the strain means79.3   % 82.8   %
Median of the strain means74.1   % 79.4   %
SD of the strain means± 10.4 ± 9.32
Coefficient of variation (CV)0.131 0.113
Min–max range of strain means71.4   –   95.3   % 73.8   –   94.8   %
Mean sample size per strain5.7   mice 9.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 64.2973 64.2973 1.5944 0.2105
strain 4 6853.2073 1713.3018 42.4851 < 0.0001
sex:strain 4 163.0847 40.7712 1.011 0.407
Residuals 78 3145.518 40.3272


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 74.2 3.58   4 1.79 0.0483 70.8, 78.3 -0.49
129S1/SvImJ m 78.8 9.32   9 3.11 0.118 70.7, 95.6 -0.43
C57BL/6J f 74.1 3.47   4 1.74 0.0469 70.0, 78.5 -0.5
C57BL/6J m 75.2 4.29   8 1.52 0.0571 70.2, 80.7 -0.81
CAST/EiJ f 72.8 1.44   2   1.02 0.0197 71.8, 73.8 -0.62
NOD/ShiLtJ f 73.5 2.9   7 1.1 0.0395 70.3, 77.3 -0.55
NOD/ShiLtJ m 80.0 9.99   15 2.58 0.125 72.2, 103.0 -0.3
NZO/HlLtJ f 93.6 4.54   10 1.44 0.0485 85.6, 99.3 1.37
NZO/HlLtJ m 94.1 4.78   9 1.59 0.0508 89.3, 104.0 1.21
PWK/PhJ f 95.3 4.83   12 1.39 0.0506 90.0, 104.0 1.54
PWK/PhJ m 94.8 4.41   10 1.39 0.0465 90.4, 103.0 1.29
WSB/EiJ f 71.4 0.0   1   0.0 0.0 71.4, 71.4 -0.76
WSB/EiJ m 73.8 2.36   3 1.36 0.032 71.6, 76.3 -0.96


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 74.1525 3.1752 80.4738 67.8312
129S1/SvImJ m 78.7667 2.1168 82.9809 74.5525
C57BL/6J f 74.11 3.1752 80.4313 67.7887
C57BL/6J m 75.1787 2.2452 79.6486 70.7089
NOD/ShiLtJ f 73.4829 2.4002 78.2613 68.7044
NOD/ShiLtJ m 80.0007 1.6397 83.265 76.7364
NZO/HlLtJ f 93.613 2.0082 97.6109 89.6151
NZO/HlLtJ m 94.0667 2.1168 98.2809 89.8525
PWK/PhJ f 95.3 1.8332 98.9496 91.6504
PWK/PhJ m 94.786 2.0082 98.7839 90.7881


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 76.4596 1.908 80.2582 72.661
C57BL/6J both 74.6444 1.9444 78.5154 70.7734
NOD/ShiLtJ both 76.7418 1.4534 79.6353 73.8483
NZO/HlLtJ both 93.8398 1.4589 96.7443 90.9354
PWK/PhJ both 95.043 1.3595 97.7496 92.3364




  GWAS USING LINEAR MIXED MODELS