Project measure / variable:   Schughart3   pctbwA_d8

ID, description, units MPD:57118   pctbwA_d8   body weight as percent of baseline, 10 FFU group   [%]  post-infection day 8  
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   7 strains     sex: both     age: 7-13wks
Procedure body weight
Ontology mappings

  STRAIN COMPARISON PLOT
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Schughart3 - body weight as percent of baseline, 10 FFU group post-infection day 8



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means80.1   % 82.9   %
Median of the strain means75.0   % 81.0   %
SD of the strain means± 10.8 ± 9.01
Coefficient of variation (CV)0.134 0.109
Min–max range of strain means72.0   –   97.0   % 72.8   –   95.9   %
Mean sample size per strain7.1   mice 9.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.3271 2.3271 0.0744 0.7856
strain 6 9423.2313 1570.5385 50.2024 < 0.0001
sex:strain 6 276.4336 46.0723 1.4727 0.1951
Residuals 101 3159.6955 31.2841


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 76.0 6.24   6 2.55 0.0821 70.9, 87.3 -0.38
129S1/SvImJ m 82.1 7.48   11 2.26 0.0911 73.1, 96.6 -0.09
C57BL/6J f 75.0 4.26   7 1.61 0.0569 70.2, 82.5 -0.47
C57BL/6J m 78.2 5.03   9 1.68 0.0642 72.6, 85.9 -0.52
CAST/EiJ f 72.5 1.42   3 0.818 0.0195 70.8, 73.5 -0.7
CAST/EiJ m 72.8 1.3   3 0.748 0.0178 72.0, 74.3 -1.12
NOD/ShiLtJ f 73.7 2.48   8 0.879 0.0337 70.6, 76.8 -0.59
NOD/ShiLtJ m 81.0 8.63   15 2.23 0.107 74.0, 101.0 -0.21
NZO/HlLtJ f 94.3 4.94   10 1.56 0.0524 86.2, 100.0 1.32
NZO/HlLtJ m 94.6 4.76   9 1.59 0.0503 88.6, 103.0 1.3
PWK/PhJ f 97.0 5.78   12 1.67 0.0596 89.3, 107.0 1.57
PWK/PhJ m 95.9 4.51   10 1.43 0.0471 91.0, 103.0 1.44
WSB/EiJ f 72.0 1.41   4 0.703 0.0195 70.5, 73.7 -0.75
WSB/EiJ m 75.6 2.49   8 0.88 0.0329 71.3, 78.4 -0.81


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 75.9533 2.2834 80.483 71.4236
129S1/SvImJ m 82.1245 1.6864 85.4699 78.7791
C57BL/6J f 74.9557 2.114 79.1494 70.762
C57BL/6J m 78.2478 1.8644 81.9463 74.5493
CAST/EiJ f 72.4567 3.2292 78.8626 66.0507
CAST/EiJ m 72.7833 3.2292 79.1893 66.3774
NOD/ShiLtJ f 73.6637 1.9775 77.5866 69.7409
NOD/ShiLtJ m 80.9827 1.4442 83.8475 78.1178
NZO/HlLtJ f 94.298 1.7687 97.8067 90.7893
NZO/HlLtJ m 94.6056 1.8644 98.304 90.9071
PWK/PhJ f 97.0017 1.6146 100.2046 93.7987
PWK/PhJ m 95.852 1.7687 99.3607 92.3433
WSB/EiJ f 72.0425 2.7966 77.5902 66.4948
WSB/EiJ m 75.6162 1.9775 79.5391 71.6934


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 79.0389 1.4193 81.8545 76.2234
C57BL/6J both 76.6017 1.4094 79.3975 73.806
CAST/EiJ both 72.62 2.2834 77.1497 68.0903
NOD/ShiLtJ both 77.3232 1.2243 79.752 74.8944
NZO/HlLtJ both 94.4518 1.285 97.0008 91.9028
PWK/PhJ both 96.4268 1.1974 98.8022 94.0514
WSB/EiJ both 73.8294 1.7126 77.2266 70.4321




  GWAS USING LINEAR MIXED MODELS