Project measure / variable:   Schughart3   pctbwA_d7

ID, description, units MPD:57117   pctbwA_d7   body weight as percent of baseline, 10 FFU group   [%]  post-infection day 7  
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   8 strains     sex: both     age: 7-13wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Schughart3 - body weight as percent of baseline, 10 FFU group post-infection day 7



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means80.4   % 84.3   %
Median of the strain means77.5   % 84.8   %
SD of the strain means± 9.80 ± 8.60
Coefficient of variation (CV)0.122 0.102
Min–max range of strain means71.3   –   96.0   % 72.2   –   95.6   %
Mean sample size per strain8.8   mice 9.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 381.6358 381.6358 11.4767 0.0009
strain 7 9926.45 1418.0643 42.6446 < 0.0001
sex:strain 7 565.0366 80.7195 2.4274 0.0227
Residuals 131 4356.1547 33.2531


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 77.5 5.4   9 1.8 0.0697 71.6, 86.5 -0.29
129S1/SvImJ m 87.7 8.2   11 2.47 0.0935 78.0, 102.0 0.4
A/J f 71.3 1.48   3 0.857 0.0208 70.4, 73.0 -0.93
A/J m 72.2 2.21   7 0.837 0.0306 70.2, 76.6 -1.4
C57BL/6J f 78.6 6.72   9 2.24 0.0856 70.0, 90.9 -0.18
C57BL/6J m 82.7 8.04   10 2.54 0.0972 71.4, 94.1 -0.18
CAST/EiJ f 72.7 2.41   7 0.911 0.0331 70.7, 77.1 -0.78
CAST/EiJ m 76.1 2.16   5 0.968 0.0284 74.3, 79.7 -0.95
NOD/ShiLtJ f 77.6 3.86   9 1.29 0.0498 73.6, 83.3 -0.28
NOD/ShiLtJ m 86.8 9.08   15 2.34 0.105 77.5, 103.0 0.3
NZO/HlLtJ f 95.4 4.55   10 1.44 0.0477 86.7, 101.0 1.53
NZO/HlLtJ m 95.6 6.96   9 2.32 0.0728 87.5, 108.0 1.32
PWK/PhJ f 96.0 4.25   12 1.23 0.0443 90.6, 104.0 1.59
PWK/PhJ m 95.0 4.67   10 1.48 0.0491 88.5, 101.0 1.25
WSB/EiJ f 73.9 2.53   11 0.763 0.0342 70.8, 78.2 -0.66
WSB/EiJ m 77.9 3.57   10 1.13 0.0459 73.2, 83.7 -0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 77.5067 1.9222 81.3092 73.7041
129S1/SvImJ m 87.6891 1.7387 91.1286 84.2496
A/J f 71.2767 3.3293 77.8629 64.6905
A/J m 72.2129 2.1796 76.5245 67.9012
C57BL/6J f 78.5789 1.9222 82.3814 74.7764
C57BL/6J m 82.665 1.8235 86.2724 79.0576
CAST/EiJ f 72.7243 2.1796 77.036 68.4126
CAST/EiJ m 76.11 2.5789 81.2116 71.0084
NOD/ShiLtJ f 77.5856 1.9222 81.3881 73.783
NOD/ShiLtJ m 86.752 1.4889 89.6974 83.8066
NZO/HlLtJ f 95.409 1.8235 99.0164 91.8016
NZO/HlLtJ m 95.5911 1.9222 99.3936 91.7886
PWK/PhJ f 95.9667 1.6647 99.2598 92.6736
PWK/PhJ m 94.956 1.8235 98.5634 91.3486
WSB/EiJ f 73.8918 1.7387 77.3313 70.4523
WSB/EiJ m 77.887 1.8235 81.4944 74.2796


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 82.5979 1.2959 85.1615 80.0342
A/J both 71.7448 1.9896 75.6808 67.8088
C57BL/6J both 80.6219 1.3248 83.2427 78.0012
CAST/EiJ both 74.4171 1.6883 77.7569 71.0773
NOD/ShiLtJ both 82.1688 1.2157 84.5737 79.7638
NZO/HlLtJ both 95.5001 1.3248 98.1208 92.8793
PWK/PhJ both 95.4613 1.2345 97.9036 93.0191
WSB/EiJ both 75.8894 1.2598 78.3816 73.3972




  GWAS USING LINEAR MIXED MODELS