Project measure / variable:   Schughart3   pctbwA_d4

ID, description, units MPD:57114   pctbwA_d4   body weight as percent of baseline, 10 FFU group   [%]  post-infection day 4  
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   8 strains     sex: both     age: 7-13wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Schughart3 - body weight as percent of baseline, 10 FFU group post-infection day 4



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means89.5   % 93.0   %
Median of the strain means89.9   % 93.8   %
SD of the strain means± 4.55 ± 4.32
Coefficient of variation (CV)0.0508 0.0465
Min–max range of strain means83.1   –   96.1   % 86.2   –   97.7   %
Mean sample size per strain10.5   mice 10.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 644.4473 644.4473 34.2525 < 0.0001
strain 7 2642.5407 377.5058 20.0645 < 0.0001
sex:strain 7 190.1913 27.1702 1.4441 0.1918
Residuals 150 2822.1893 18.8146


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 90.3 5.71   9 1.9 0.0632 80.4, 99.2 0.18
129S1/SvImJ m 96.5 3.38   11 1.02 0.035 90.2, 101.0 0.82
A/J f 83.1 3.1   10 0.981 0.0374 76.8, 88.7 -1.4
A/J m 86.2 1.94   10 0.613 0.0225 83.0, 89.4 -1.56
C57BL/6J f 89.6 6.27   11 1.89 0.07 81.0, 97.4 0.03
C57BL/6J m 95.4 5.77   10 1.82 0.0605 85.5, 104.0 0.57
CAST/EiJ f 86.1 5.47   10 1.73 0.0636 77.7, 96.7 -0.74
CAST/EiJ m 88.7 3.13   7 1.18 0.0353 84.4, 93.8 -0.98
NOD/ShiLtJ f 93.3 4.66   10 1.48 0.05 87.6, 101.0 0.84
NOD/ShiLtJ m 97.0 3.38   15 0.873 0.0349 91.6, 104.0 0.94
NZO/HlLtJ f 96.1 2.46   10 0.777 0.0256 91.3, 99.4 1.46
NZO/HlLtJ m 97.7 3.74   9 1.25 0.0383 92.3, 104.0 1.1
PWK/PhJ f 92.6 4.22   12 1.22 0.0456 85.5, 98.8 0.69
PWK/PhJ m 92.1 4.87   10 1.54 0.0528 85.8, 102.0 -0.2
WSB/EiJ f 84.6 3.46   12 0.999 0.0409 77.6, 89.4 -1.07
WSB/EiJ m 90.0 5.2   10 1.65 0.0578 82.5, 97.8 -0.68


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 90.2956 1.4459 93.1524 87.4387
129S1/SvImJ m 96.4745 1.3078 99.0587 93.8904
A/J f 83.077 1.3717 85.7873 80.3667
A/J m 86.2 1.3717 88.9103 83.4897
C57BL/6J f 89.6082 1.3078 92.1923 87.024
C57BL/6J m 95.38 1.3717 98.0903 92.6697
CAST/EiJ f 86.065 1.3717 88.7753 83.3547
CAST/EiJ m 88.6557 1.6395 91.8951 85.4163
NOD/ShiLtJ f 93.268 1.3717 95.9783 90.5577
NOD/ShiLtJ m 97.0267 1.12 99.2396 94.8137
NZO/HlLtJ f 96.087 1.3717 98.7973 93.3767
NZO/HlLtJ m 97.7267 1.4459 100.5835 94.8698
PWK/PhJ f 92.5725 1.2522 95.0466 90.0984
PWK/PhJ m 92.09 1.3717 94.8003 89.3797
WSB/EiJ f 84.5758 1.2522 87.05 82.1017
WSB/EiJ m 90.002 1.3717 92.7123 87.2917


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 93.3851 0.9748 95.3112 91.4589
A/J both 84.6385 0.9699 86.555 82.722
C57BL/6J both 92.4941 0.9476 94.3665 90.6217
CAST/EiJ both 87.3604 1.0688 89.4722 85.2485
NOD/ShiLtJ both 95.1473 0.8854 96.8968 93.3979
NZO/HlLtJ both 96.9068 0.9965 98.8758 94.9379
PWK/PhJ both 92.3312 0.9286 94.1661 90.4964
WSB/EiJ both 87.2889 0.9286 89.1238 85.4541




  GWAS USING LINEAR MIXED MODELS