Project measure / variable:   Schughart3   pctbwA_d1

ID, description, units MPD:57111   pctbwA_d1   body weight as percent of baseline, 10 FFU group   [%]  post-infection day 1  
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   8 strains     sex: both     age: 7-13wks
Procedure body weight
Ontology mappings

  STRAIN COMPARISON PLOT
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Schughart3 - body weight as percent of baseline, 10 FFU group post-infection day 1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means96.3   % 96.7   %
Median of the strain means96.3   % 97.3   %
SD of the strain means± 1.78 ± 2.47
Coefficient of variation (CV)0.0185 0.0256
Min–max range of strain means93.0   –   99.0   % 91.1   –   98.9   %
Mean sample size per strain10.5   mice 10.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 13.1233 13.1233 1.5069 0.2215
strain 7 565.6435 80.8062 9.2787 < 0.0001
sex:strain 7 100.6693 14.3813 1.6514 0.1253
Residuals 150 1306.3225 8.7088


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 95.1 2.62   9 0.873 0.0275 91.7, 98.9 -0.66
129S1/SvImJ m 97.1 3.53   11 1.06 0.0363 89.8, 103.0 0.15
A/J f 96.8 1.43   10 0.452 0.0148 93.6, 99.1 0.3
A/J m 95.9 0.614   10 0.194 0.00641 94.7, 96.9 -0.33
C57BL/6J f 95.9 1.79   11 0.54 0.0187 91.9, 98.7 -0.21
C57BL/6J m 97.5 1.58   10 0.501 0.0163 95.6, 101.0 0.31
CAST/EiJ f 97.0 1.73   10 0.547 0.0178 94.1, 99.0 0.41
CAST/EiJ m 98.9 2.32   7 0.877 0.0235 94.6, 102.0 0.88
NOD/ShiLtJ f 99.0 3.9   10 1.23 0.0394 92.9, 105.0 1.53
NOD/ShiLtJ m 98.4 2.03   15 0.523 0.0206 94.8, 101.0 0.68
NZO/HlLtJ f 97.5 3.96   10 1.25 0.0407 91.2, 106.0 0.69
NZO/HlLtJ m 96.7 3.41   9 1.14 0.0353 93.4, 103.0 -0.01
PWK/PhJ f 93.0 3.94   12 1.14 0.0423 87.7, 102.0 -1.84
PWK/PhJ m 91.1 4.12   10 1.3 0.0453 85.3, 98.2 -2.28
WSB/EiJ f 95.9 4.48   12 1.29 0.0467 87.4, 102.0 -0.21
WSB/EiJ m 98.2 1.41   10 0.445 0.0143 95.9, 101.0 0.6


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 95.0533 0.9837 96.997 93.1097
129S1/SvImJ m 97.0609 0.8898 98.819 95.3028
A/J f 96.826 0.9332 98.6699 94.9821
A/J m 95.905 0.9332 97.7489 94.0611
C57BL/6J f 95.8609 0.8898 97.619 94.1028
C57BL/6J m 97.511 0.9332 99.3549 95.6671
CAST/EiJ f 97.023 0.9332 98.8669 95.1791
CAST/EiJ m 98.8957 1.1154 101.0996 96.6918
NOD/ShiLtJ f 98.953 0.9332 100.7969 97.1091
NOD/ShiLtJ m 98.4067 0.762 99.9122 96.9011
NZO/HlLtJ f 97.476 0.9332 99.3199 95.6321
NZO/HlLtJ m 96.7022 0.9837 98.6459 94.7585
PWK/PhJ f 93.0342 0.8519 94.7174 91.3509
PWK/PhJ m 91.09 0.9332 92.9339 89.2461
WSB/EiJ f 95.8842 0.8519 97.5674 94.2009
WSB/EiJ m 98.207 0.9332 100.0509 96.3631


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 96.0571 0.6632 97.3675 94.7467
A/J both 96.3655 0.6599 97.6694 95.0616
C57BL/6J both 96.686 0.6447 97.9598 95.4121
CAST/EiJ both 97.9594 0.7272 99.3961 96.5226
NOD/ShiLtJ both 98.6798 0.6024 99.8701 97.4896
NZO/HlLtJ both 97.0891 0.678 98.4287 95.7495
PWK/PhJ both 92.0621 0.6318 93.3104 90.8137
WSB/EiJ both 97.0456 0.6318 98.2939 95.7972




  GWAS USING LINEAR MIXED MODELS