Project measure / variable:   GMC20   IgA_21

ID, description, units MPD:56905   IgA_21   immunoglobulin A (plasma IgA)   [µg/mL]  at age 20-21wks  
Data set, strains GMC20   inbred w/CC8   8 strains     sex: both     age: 20-21wks
Procedure immunoglobulin quantification
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  STRAIN COMPARISON PLOT
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GMC20 - immunoglobulin A (plasma IgA) at age 20-21wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means973   µg/mL 1120   µg/mL
Median of the strain means905   µg/mL 1190   µg/mL
SD of the strain means± 214 ± 219
Coefficient of variation (CV)0.220 0.196
Min–max range of strain means770   –   1405   µg/mL 813   –   1416   µg/mL
Mean sample size per strain6.9   mice 7.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1337178.0532 1337178.0532 3.6606 0.0586
strain 6 1076080.1495 179346.6916 0.491 0.8137
sex:strain 6 2275856.3715 379309.3952 1.0384 0.4053
Residuals 98 35798776.0729 365293.6334


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 911.0 648.0   8 229.0 0.711 454.0, 2271.0 -0.29
129S1/SvImJ m 1209.0 669.0   8 236.0 0.553 634.0, 2247.0 0.4
A/J f 770.0 696.0   9 232.0 0.904 302.0, 2526.0 -0.95
A/J m 1217.0 746.0   10 236.0 0.613 504.0, 2406.0 0.44
C57BL/6J f 846.0 453.0   8 160.0 0.535 557.0, 1939.0 -0.59
C57BL/6J m 1306.0 547.0   11 165.0 0.419 620.0, 2102.0 0.85
CAST/EiJ f 1057.0 461.0   8 163.0 0.436 285.0, 1616.0 0.39
CAST/EiJ m 813.0 390.0   9 130.0 0.48 279.0, 1696.0 -1.4
NOD/ShiLtJ f 1405.0 222.0   2   157.0 0.158 1248.0, 1563.0 2.02
NOD/ShiLtJ m 1172.0 0.0   1   0.0 0.0 1172.0, 1172.0 0.24
NZO/HlLtJ f 899.0 724.0   7 273.0 0.805 58.7, 1850.0 -0.34
NZO/HlLtJ m 1416.0 798.0   7 302.0 0.564 269.0, 2306.0 1.35
PWK/PhJ f 775.0 509.0   6 208.0 0.657 196.0, 1482.0 -0.92
PWK/PhJ m 825.0 323.0   5 144.0 0.391 373.0, 1164.0 -1.35
WSB/EiJ f 1120.0 541.0   7 204.0 0.483 271.0, 1887.0 0.69
WSB/EiJ m 1004.0 642.0   9 214.0 0.64 344.0, 1987.0 -0.53


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 911.3512 213.686 1335.4042 487.2983
129S1/SvImJ m 1208.8487 213.686 1632.9017 784.7958
A/J f 769.55 201.4651 1169.3509 369.7491
A/J m 1216.546 191.1266 1595.8304 837.2616
C57BL/6J f 845.685 213.686 1269.7379 421.6321
C57BL/6J m 1305.9518 182.232 1667.5853 944.3183
CAST/EiJ f 1056.5125 213.686 1480.5654 632.4596
CAST/EiJ m 812.7911 201.4651 1212.592 412.9902
NZO/HlLtJ f 899.1 228.4399 1352.4316 445.7684
NZO/HlLtJ m 1415.7271 228.4399 1869.0588 962.3955
PWK/PhJ f 774.7317 246.7433 1264.3858 285.0776
PWK/PhJ m 824.978 270.2938 1361.3672 288.5888
WSB/EiJ f 1119.7857 228.4399 1573.1173 666.4541
WSB/EiJ m 1003.7056 201.4651 1403.5065 603.9046


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1060.1 151.0988 1359.9507 760.2493
A/J both 993.048 138.8502 1268.5918 717.5042
C57BL/6J both 1075.8184 140.4192 1354.4758 797.1611
CAST/EiJ both 934.6518 146.8417 1226.0543 643.2493
NZO/HlLtJ both 1157.4136 161.5314 1477.9674 836.8597
PWK/PhJ both 799.8548 182.9898 1162.992 436.7176
WSB/EiJ both 1061.7456 152.2933 1363.9667 759.5246




  GWAS USING LINEAR MIXED MODELS