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Project measure / variable:   GMC16   iron_17

ID, description, units MPD:56514   iron_17   iron (plasma Fe)   [µmol/L]  at age 16-17wks  
Data set, strains GMC16   inbred w/CC8   7 strains     sex: both     age: 16-17wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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GMC16 - iron (plasma Fe) at age 16-17wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means35.4   µmol/L 33.5   µmol/L
Median of the strain means35.3   µmol/L 36.9   µmol/L
SD of the strain means± 8.87 ± 7.28
Coefficient of variation (CV)0.251 0.217
Min–max range of strain means25.2   –   48.6   µmol/L 19.8   –   40.2   µmol/L
Mean sample size per strain3.5   mice 3.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 19.8075 19.8075 2.0046 0.1675
strain 4 1269.2324 317.3081 32.1135 < 0.0001
sex:strain 4 318.8267 79.7067 8.0668 0.0002
Residuals 29 286.5442 9.8808


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 36.4 3.92   4 1.96 0.108 32.5, 41.6 0.12
129S1/SvImJ m 37.4 2.7   4 1.35 0.0722 34.7, 39.7 0.53
A/J f 41.2 4.26   4 2.13 0.103 35.5, 45.5 0.66
A/J m 36.9 2.51   4 1.26 0.0681 34.7, 39.1 0.46
C57BL/6J f 26.5 2.34   4 1.17 0.0882 23.3, 28.6 -1.0
C57BL/6J m 19.8 1.51   4 0.755 0.0764 17.8, 21.4 -1.89
NOD/ShiLtJ f 25.2 4.86   4 2.43 0.193 19.7, 30.3 -1.15
NOD/ShiLtJ m 33.6 1.87   4 0.935 0.0556 30.8, 34.6 0.01
NZO/HlLtJ f 34.3 1.64   4 0.822 0.0479 32.9, 36.5 -0.12
NZO/HlLtJ m 28.0 4.03   3 2.33 0.144 25.3, 32.6 -0.76
PWK/PhJ m 40.2 0.0   1   0.0 0.0 40.2, 40.2 0.92
WSB/EiJ f 48.6 0.0   1   0.0 0.0 48.6, 48.6 1.49
WSB/EiJ m 38.8 5.07   3 2.93 0.131 33.5, 43.6 0.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 36.375 1.5717 39.5895 33.1605
129S1/SvImJ m 37.375 1.5717 40.5895 34.1605
A/J f 41.175 1.5717 44.3895 37.9605
A/J m 36.875 1.5717 40.0895 33.6605
C57BL/6J f 26.5 1.5717 29.7145 23.2855
C57BL/6J m 19.775 1.5717 22.9895 16.5605
NOD/ShiLtJ f 25.2 1.5717 28.4145 21.9855
NOD/ShiLtJ m 33.6 1.5717 36.8145 30.3855
NZO/HlLtJ f 34.3 1.5717 37.5145 31.0855
NZO/HlLtJ m 27.9667 1.8148 31.6784 24.2549


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 36.875 1.1114 39.148 34.602
A/J both 39.025 1.1114 41.298 36.752
C57BL/6J both 23.1375 1.1114 25.4105 20.8645
NOD/ShiLtJ both 29.4 1.1114 31.673 27.127
NZO/HlLtJ both 31.1333 1.2004 33.5884 28.6782




  GWAS USING LINEAR MIXED MODELS