Project measure / variable:   GMC10   fat_13wk

ID, description, units MPD:55911   fat_13wk   fat tissue mass, whole body with head (NMR)   [g]  at age 12-13wks  
Data set, strains GMC10   inbred w/CC8   8 strains     sex: both     age: 12-13wks
Procedure NMR
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  STRAIN COMPARISON PLOT
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GMC10 - fat tissue mass, whole body with head (NMR) at age 12-13wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means5.52   g 6.38   g
Median of the strain means4.35   g 5.17   g
SD of the strain means± 5.33 ± 5.53
Coefficient of variation (CV)0.967 0.866
Min–max range of strain means2.06   –   18.4   g 2.42   –   19.6   g
Mean sample size per strain17.4   mice 15.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 7.7576 7.7576 8.1752 0.0046
strain 7 5598.5383 799.7912 842.8422 < 0.0001
sex:strain 7 8.108 1.1583 1.2206 0.2918
Residuals 249 236.2815 0.9489


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 4.26 0.563   16 0.141 0.132 3.4, 5.2 -0.24
129S1/SvImJ m 5.44 0.8   16 0.2 0.147 4.4, 7.1 -0.17
A/J f 4.44 0.612   16 0.153 0.138 3.1, 5.4 -0.2
A/J m 4.9 0.862   16 0.215 0.176 3.5, 6.6 -0.27
C57BL/6J f 4.74 0.62   16 0.155 0.131 4.1, 6.6 -0.15
C57BL/6J m 6.16 0.521   16 0.13 0.0847 5.1, 6.9 -0.04
CAST/EiJ f 2.53 0.281   19 0.0645 0.111 2.1, 3.1 -0.56
CAST/EiJ m 3.09 0.674   16 0.169 0.218 1.5, 3.9 -0.6
NOD/ShiLtJ f 5.17 0.798   18 0.188 0.154 4.1, 7.3 -0.06
NOD/ShiLtJ m 6.15 0.649   16 0.162 0.106 5.4, 7.4 -0.04
NZO/HlLtJ f 18.4 2.78   16 0.694 0.151 12.8, 22.9 2.41
NZO/HlLtJ m 19.6 2.13   10 0.673 0.109 16.1, 23.0 2.39
PWK/PhJ f 2.53 0.351   20 0.0785 0.139 2.0, 3.1 -0.56
PWK/PhJ m 3.32 0.528   20 0.118 0.159 2.4, 4.2 -0.55
WSB/EiJ f 2.06 0.426   18 0.1 0.207 1.3, 3.1 -0.65
WSB/EiJ m 2.42 0.442   16 0.11 0.182 1.9, 3.4 -0.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 4.2563 0.2435 4.7359 3.7766
129S1/SvImJ m 5.4438 0.2435 5.9234 4.9641
A/J f 4.4438 0.2435 4.9234 3.9641
A/J m 4.9 0.2435 5.3796 4.4204
C57BL/6J f 4.7438 0.2435 5.2234 4.2641
C57BL/6J m 6.1563 0.2435 6.6359 5.6766
CAST/EiJ f 2.5316 0.2235 2.9717 2.0914
CAST/EiJ m 3.0875 0.2435 3.5671 2.6079
NOD/ShiLtJ f 5.1722 0.2296 5.6244 4.72
NOD/ShiLtJ m 6.15 0.2435 6.6296 5.6704
NZO/HlLtJ f 18.4125 0.2435 18.8921 17.9329
NZO/HlLtJ m 19.56 0.308 20.1667 18.9533
PWK/PhJ f 2.53 0.2178 2.959 2.101
PWK/PhJ m 3.32 0.2178 3.749 2.891
WSB/EiJ f 2.0556 0.2296 2.5078 1.6033
WSB/EiJ m 2.425 0.2435 2.9046 1.9454


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 4.85 0.1722 5.1892 4.5108
A/J both 4.6719 0.1722 5.011 4.3327
C57BL/6J both 5.45 0.1722 5.7892 5.1108
CAST/EiJ both 2.8095 0.1653 3.135 2.484
NOD/ShiLtJ both 5.6611 0.1674 5.9907 5.3315
NZO/HlLtJ both 18.9863 0.1963 19.373 18.5995
PWK/PhJ both 2.925 0.154 3.2284 2.6216
WSB/EiJ both 2.2403 0.1674 2.5699 1.9107




  GWAS USING LINEAR MIXED MODELS