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Project measure / variable:   GMC09   VCO2_mean

ID, description, units MPD:55832   VCO2_mean   mean carbon dioxide production, 21 h test, 15 min bins   [mL/h]  
Data set, strains GMC09   inbred w/CC8   8 strains     sex: both     age: 12-13wks
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  STRAIN COMPARISON PLOT
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GMC09 - mean carbon dioxide production, 21 h test, 15 min bins



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means63.1   mL/h 68.3   mL/h
Median of the strain means58.5   mL/h 64.6   mL/h
SD of the strain means± 14.4 ± 15.8
Coefficient of variation (CV)0.227 0.231
Min–max range of strain means46.2   –   90.2   mL/h 48.9   –   97.3   mL/h
Mean sample size per strain17.5   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1936.0486 1936.0486 37.5617 < 0.0001
strain 7 52155.0743 7450.7249 144.553 < 0.0001
sex:strain 7 1067.1748 152.4535 2.9578 0.0054
Residuals 255 13143.5178 51.5432


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 46.2 9.57   16 2.39 0.207 32.0, 64.0 -1.18
129S1/SvImJ m 48.9 8.57   16 2.14 0.175 36.0, 64.0 -1.23
A/J f 51.7 5.76   16 1.44 0.111 42.0, 67.0 -0.79
A/J m 54.6 6.36   16 1.59 0.116 45.0, 66.0 -0.87
C57BL/6J f 64.9 3.34   16 0.834 0.0514 59.0, 70.0 0.13
C57BL/6J m 77.9 8.32   16 2.08 0.107 59.0, 93.0 0.61
CAST/EiJ f 57.2 4.79   19 1.1 0.0837 47.0, 65.0 -0.41
CAST/EiJ m 63.4 6.0   14 1.6 0.0945 50.0, 71.0 -0.31
NOD/ShiLtJ f 77.6 9.38   18 2.21 0.121 62.0, 98.0 1.01
NOD/ShiLtJ m 79.6 6.46   16 1.61 0.0811 62.0, 87.0 0.72
NZO/HlLtJ f 90.2 7.93   17 1.92 0.0878 74.0, 104.0 1.89
NZO/HlLtJ m 97.3 8.83   17 2.14 0.0908 83.0, 114.0 1.84
PWK/PhJ f 57.6 5.1   20 1.14 0.0885 47.0, 68.0 -0.38
PWK/PhJ m 65.8 6.72   20 1.5 0.102 55.0, 78.0 -0.16
WSB/EiJ f 59.4 9.11   18 2.15 0.153 42.0, 78.0 -0.26
WSB/EiJ m 58.9 4.75   16 1.19 0.0807 51.0, 67.0 -0.6


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 46.25 1.7948 49.7846 42.7154
129S1/SvImJ m 48.875 1.7948 52.4096 45.3404
A/J f 51.6875 1.7948 55.2221 48.1529
A/J m 54.5625 1.7948 58.0971 51.0279
C57BL/6J f 64.9375 1.7948 68.4721 61.4029
C57BL/6J m 77.9375 1.7948 81.4721 74.4029
CAST/EiJ f 57.2105 1.6471 60.4541 53.967
CAST/EiJ m 63.4286 1.9188 67.2072 59.6499
NOD/ShiLtJ f 77.6111 1.6922 80.9436 74.2787
NOD/ShiLtJ m 79.625 1.7948 83.1596 76.0904
NZO/HlLtJ f 90.2353 1.7413 93.6644 86.8062
NZO/HlLtJ m 97.2941 1.7413 100.7232 93.8651
PWK/PhJ f 57.65 1.6054 60.8114 54.4886
PWK/PhJ m 65.85 1.6054 69.0114 62.6886
WSB/EiJ f 59.3889 1.6922 62.7213 56.0564
WSB/EiJ m 58.9375 1.7948 62.4721 55.4029


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 47.5625 1.2691 50.0618 45.0632
A/J both 53.125 1.2691 55.6243 50.6257
C57BL/6J both 71.4375 1.2691 73.9368 68.9382
CAST/EiJ both 60.3195 1.2644 62.8095 57.8296
NOD/ShiLtJ both 78.6181 1.2334 81.047 76.1891
NZO/HlLtJ both 93.7647 1.2313 96.1894 91.34
PWK/PhJ both 61.75 1.1352 63.9855 59.5145
WSB/EiJ both 59.1632 1.2334 61.5921 56.7343




  GWAS USING LINEAR MIXED MODELS