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Project measure / variable:   Rusyn6   TCA_kidney_tce

ID, description, units MPD:51258   TCA_kidney_tce   trichloroacetic acid (kidney TCA)   [nmol/g]  
trichloroethylene study
Data set, strains Rusyn6   inbred   7 strains     sex: m     age: 6-7wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn6 - trichloroacetic acid (kidney TCA)



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested7 strains
Mean of the strain means635   nmol/g
Median of the strain means530   nmol/g
SD of the strain means± 421
Coefficient of variation (CV)0.662
Min–max range of strain means192   –   1239   nmol/g
Mean sample size per strain3.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 6 3801182.5522 633530.4254 6.8064 0.0006
Residuals 19 1768486.0067 93078.2109


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 530.0 116.0   4 58.2 0.22 362.0, 632.0 -0.25
A/J m 192.0 121.0   4 60.4 0.628 63.0, 306.0 -1.05
BTBR T+ Itpr3tf/J m 1148.0 435.0   3 251.0 0.379 676.0, 1534.0 1.22
C57BL/6J m 419.0 122.0   4 60.9 0.29 290.0, 580.0 -0.51
CAST/EiJ m 217.0 86.2   3 49.8 0.397 127.0, 299.0 -0.99
NOD/ShiLtJ m 701.0 235.0   4 118.0 0.335 408.0, 944.0 0.16
NZW/LacJ m 1239.0 600.0   4 300.0 0.484 514.0, 1878.0 1.44


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 529.675 152.5436 848.9524 210.3976
A/J m 192.325 152.5436 511.6024 0.0
BTBR T+ Itpr3tf/J m 1147.5 176.1422 1516.1698 778.8302
C57BL/6J m 419.125 152.5436 738.4024 99.8476
CAST/EiJ m 216.9333 176.1422 585.6032 0.0
NOD/ShiLtJ m 701.35 152.5436 1020.6274 382.0726
NZW/LacJ m 1238.525 152.5436 1557.8024 919.2476




  GWAS USING LINEAR MIXED MODELS