Project measure / variable:   Rusyn6   KIM1_kidney_tce

ID, description, units MPD:51256   KIM1_kidney_tce   kidney injury molecule 1 (KIM-1) positive proximal tubules   [%]  TCE  
trichloroethylene study
Data set, strains Rusyn6   inbred   7 strains     sex: m     age: 6-7wks
Procedure histopathology
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  STRAIN COMPARISON PLOT
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Rusyn6 - kidney injury molecule 1 (KIM-1) positive proximal tubules TCE



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested7 strains
Mean of the strain means11.2   %
Median of the strain means9.40   %
SD of the strain means± 10.2
Coefficient of variation (CV)0.908
Min–max range of strain means0   –   24.6   %
Mean sample size per strain3.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 6 2355.6132 392.6022 1.8004 0.1501
Residuals 20 4361.2275 218.0614


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 12.8 13.3   4 6.64 1.04 2.4, 32.3 0.16
A/J m 9.4 10.1   4 5.04 1.07 0.7, 20.7 -0.18
BTBR T+ Itpr3tf/J m 7.35 2.88   4 1.44 0.391 4.4, 11.3 -0.38
C57BL/6J m 24.2 25.1   4 12.5 1.03 2.0, 48.2 1.28
CAST/EiJ m 0.0 0.0   3 0.0 0.0 -1.1
NOD/ShiLtJ m 0.0 0.0   4 0.0 0.0 -1.1
NZW/LacJ m 24.6 23.2   4 11.6 0.943 1.0, 52.1 1.32


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 12.825 7.3835 28.2266 -2.5766
A/J m 9.4 7.3835 24.8016 -6.0016
BTBR T+ Itpr3tf/J m 7.35 7.3835 22.7516 -8.0516
C57BL/6J m 24.25 7.3835 39.6516 8.8484
CAST/EiJ m 0.0 8.5257 17.7842 -17.7842
NOD/ShiLtJ m 0.0 7.3835 15.4016 -15.4016
NZW/LacJ m 24.6 7.3835 40.0016 9.1984




  GWAS USING LINEAR MIXED MODELS