Project measure / variable:   HMDPpheno7   lactone

ID, description, units MPD:50227   lactone   liver gulono-1,4-lactone (16h fast), relative abundance    
Data set, strains HMDPpheno7   HMDP   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings


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  STRAIN COMPARISON PLOT
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HMDPpheno7 - liver gulono-1,4-lactone (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means3072047   None
Median of the strain means2295804   None
SD of the strain means± 2443837
Coefficient of variation (CV)0.796
Min–max range of strain means908475   –   14649897   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 74544284225447.9 3549727820259.42 3.5208 0.0005
Residuals 34 34279084203173.5 1008208358916.87


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 2138346.0 0.0   1   0.0 0.0 2138346.0, 2138346.0 -0.38
A/J m 1882052.0 356392.0   2   252007.0 0.189 1630045.0, 2134060.0 -0.49
AKR/J m 1282850.0 0.0   1   0.0 0.0 1282850.0, 1282850.0 -0.73
AXB10/PgnJ m 2479551.0 0.0   1   0.0 0.0 2479551.0, 2479551.0 -0.24
AXB12/PgnJ m 1615540.0 0.0   1   0.0 0.0 1615540.0, 1615540.0 -0.6
AXB13/PgnJ m 1589576.0 0.0   1   0.0 0.0 1589576.0, 1589576.0 -0.61
AXB15/PgnJ m 2040584.0 0.0   1   0.0 0.0 2040584.0, 2040584.0 -0.42
AXB19a/PgnJ m 1997483.0 0.0   1   0.0 0.0 1997483.0, 1997483.0 -0.44
AXB19b/PgnJ m 2842095.0 746453.0   2   527822.0 0.263 2314274.0, 3369917.0 -0.09
AXB19/PgnJ m 3745230.0 0.0   1   0.0 0.0 3745230.0, 3745230.0 0.28
AXB1/PgnJ m 2093026.0 0.0   1   0.0 0.0 2093026.0, 2093026.0 -0.4
AXB23/PgnJ m 1625956.0 0.0   1   0.0 0.0 1625956.0, 1625956.0 -0.59
AXB24/PgnJ m 1308404.0 85978.0   2   60796.0 0.0657 1247608.0, 1369200.0 -0.72
AXB2/PgnJ m 2322578.0 0.0   1   0.0 0.0 2322578.0, 2322578.0 -0.31
AXB4/PgnJ m 1870718.0 0.0   1   0.0 0.0 1870718.0, 1870718.0 -0.49
AXB5/PgnJ m 1027839.0 0.0   1   0.0 0.0 1027839.0, 1027839.0 -0.84
AXB6/PgnJ m 2273006.0 0.0   1   0.0 0.0 2273006.0, 2273006.0 -0.33
AXB8/PgnJ m 2536634.0 0.0   1   0.0 0.0 2536634.0, 2536634.0 -0.22
BALB/cJ m 3593384.0 427426.0   3 246775.0 0.119 3118876.0, 3948219.0 0.21
BTBR T+ Itpr3tf/J m 1531869.0 0.0   1   0.0 0.0 1531869.0, 1531869.0 -0.63
BUB/BnJ m 2325810.0 0.0   1   0.0 0.0 2325810.0, 2325810.0 -0.31
BXA11/PgnJ m 2013594.0 0.0   1   0.0 0.0 2013594.0, 2013594.0 -0.43
BXA12/PgnJ m 2475632.0 0.0   1   0.0 0.0 2475632.0, 2475632.0 -0.24
BXA13/PgnJ m 2588008.0 0.0   1   0.0 0.0 2588008.0, 2588008.0 -0.2
BXA14/PgnJ m 2101085.0 0.0   1   0.0 0.0 2101085.0, 2101085.0 -0.4
BXA16/PgnJ m 4518151.0 3171851.0   2   2242837.0 0.702 2275314.0, 6760988.0 0.59
BXA1/PgnJ m 1843717.0 0.0   1   0.0 0.0 1843717.0, 1843717.0 -0.5
BXA24/PgnJ m 2531262.0 0.0   1   0.0 0.0 2531262.0, 2531262.0 -0.22
BXA25/PgnJ m 1642449.0 0.0   1   0.0 0.0 1642449.0, 1642449.0 -0.58
BXA26/PgnJ m 2082652.0 0.0   1   0.0 0.0 2082652.0, 2082652.0 -0.4
BXA2/PgnJ m 2356575.0 0.0   1   0.0 0.0 2356575.0, 2356575.0 -0.29
BXA4/PgnJ m 2069892.0 0.0   1   0.0 0.0 2069892.0, 2069892.0 -0.41
BXA7/PgnJ m 2337104.0 0.0   1   0.0 0.0 2337104.0, 2337104.0 -0.3
BXA8/PgnJ m 2154478.0 0.0   1   0.0 0.0 2154478.0, 2154478.0 -0.38
BXD11/TyJ m 3345108.0 0.0   1   0.0 0.0 3345108.0, 3345108.0 0.11
BXD12/TyJ m 2728954.0 0.0   1   0.0 0.0 2728954.0, 2728954.0 -0.14
BXD13/TyJ m 2288945.0 0.0   1   0.0 0.0 2288945.0, 2288945.0 -0.32
BXD14/TyJ m 2806265.0 0.0   1   0.0 0.0 2806265.0, 2806265.0 -0.11
BXD15/TyJ m 3948098.0 0.0   1   0.0 0.0 3948098.0, 3948098.0 0.36
BXD18/TyJ m 4056282.0 0.0   1   0.0 0.0 4056282.0, 4056282.0 0.4
BXD19/TyJ m 4921914.0 3990890.0   2   2821986.0 0.811 2099929.0, 7743900.0 0.76
BXD1/TyJ m 11725310.0 0.0   1   0.0 0.0 11725310.0, 11725310.0 3.54
BXD20/TyJ m 9153473.0 0.0   1   0.0 0.0 9153473.0, 9153473.0 2.49
BXD21/TyJ m 5436910.0 0.0   1   0.0 0.0 5436910.0, 5436910.0 0.97
BXD22/TyJ m 2962044.0 0.0   1   0.0 0.0 2962044.0, 2962044.0 -0.05
BXD24/TyJ m 4027142.0 0.0   1   0.0 0.0 4027142.0, 4027142.0 0.39
BXD24/TyJ-Cep290rd16/J m 5595862.0 0.0   1   0.0 0.0 5595862.0, 5595862.0 1.03
BXD28/TyJ m 1740475.0 279198.0   2   197423.0 0.16 1543052.0, 1937898.0 -0.54
BXD29-Tlr4lps-2J/J m 8214997.0 0.0   1   0.0 0.0 8214997.0, 8214997.0 2.1
BXD2/TyJ m 1966314.0 0.0   1   0.0 0.0 1966314.0, 1966314.0 -0.45
BXD32/TyJ m 2559970.0 0.0   1   0.0 0.0 2559970.0, 2559970.0 -0.21
BXD33/TyJ m 10083591.0 0.0   1   0.0 0.0 10083591.0, 10083591.0 2.87
BXD34/TyJ m 1494547.0 0.0   1   0.0 0.0 1494547.0, 1494547.0 -0.65
BXD36/TyJ m 908475.0 0.0   1   0.0 0.0 908475.0, 908475.0 -0.89
BXD38/TyJ m 10074717.0 0.0   1   0.0 0.0 10074717.0, 10074717.0 2.87
BXD39/TyJ m 6963800.0 0.0   1   0.0 0.0 6963800.0, 6963800.0 1.59
BXD40/TyJ m 1789806.0 0.0   1   0.0 0.0 1789806.0, 1789806.0 -0.52
BXD42/TyJ m 14649897.0 0.0   1   0.0 0.0 14649897.0, 14649897.0 4.74
BXD5/TyJ m 4354600.0 0.0   1   0.0 0.0 4354600.0, 4354600.0 0.52
BXD6/TyJ m 2935585.0 0.0   1   0.0 0.0 2935585.0, 2935585.0 -0.06
BXD8/TyJ m 7961739.0 0.0   1   0.0 0.0 7961739.0, 7961739.0 2.0
BXD9/TyJ m 1645713.0 0.0   1   0.0 0.0 1645713.0, 1645713.0 -0.58
BXH10/TyJ m 1298403.0 0.0   1   0.0 0.0 1298403.0, 1298403.0 -0.73
BXH19/TyJ m 2054429.0 0.0   1   0.0 0.0 2054429.0, 2054429.0 -0.42
BXH20/KccJ m 2245140.0 0.0   1   0.0 0.0 2245140.0, 2245140.0 -0.34
BXH22/KccJ m 1859267.0 0.0   1   0.0 0.0 1859267.0, 1859267.0 -0.5
BXH2/TyJ m 2302664.0 0.0   1   0.0 0.0 2302664.0, 2302664.0 -0.31
BXH4/TyJ m 2058508.0 82005.0   2   57987.0 0.0398 2000522.0, 2116495.0 -0.41
BXH6/TyJ m 1415709.0 0.0   1   0.0 0.0 1415709.0, 1415709.0 -0.68
BXH7/TyJ m 1651109.0 0.0   1   0.0 0.0 1651109.0, 1651109.0 -0.58
BXH8/TyJ m 1431554.0 0.0   1   0.0 0.0 1431554.0, 1431554.0 -0.67
BXH9/TyJ m 1841774.0 0.0   1   0.0 0.0 1841774.0, 1841774.0 -0.5
C3H/HeJ m 2189278.0 806671.0   2   570402.0 0.368 1618876.0, 2759681.0 -0.36
C57BL/6J m 2713195.0 360739.0   5 161327.0 0.133 2308554.0, 3120092.0 -0.15
C57L/J m 2319847.0 0.0   1   0.0 0.0 2319847.0, 2319847.0 -0.31
C58/J m 1148469.0 0.0   1   0.0 0.0 1148469.0, 1148469.0 -0.79
CAST/EiJ m 1599367.0 0.0   1   0.0 0.0 1599367.0, 1599367.0 -0.6
CBA/J m 1216394.0 0.0   1   0.0 0.0 1216394.0, 1216394.0 -0.76
CE/J m 1934647.0 0.0   1   0.0 0.0 1934647.0, 1934647.0 -0.47
CXB11/HiAJ m 1978871.0 110377.0   2   78048.0 0.0558 1900823.0, 2056919.0 -0.45
CXB12/HiAJ m 2775709.0 302319.0   2   213772.0 0.109 2561937.0, 2989482.0 -0.12
CXB13/HiAJ m 2594802.0 779743.0   3 450185.0 0.301 2080881.0, 3492008.0 -0.2
CXB1/ByJ m 2417508.0 334511.0   3 193130.0 0.138 2140362.0, 2789083.0 -0.27
CXB2/ByJ m 3030908.0 541829.0   3 312825.0 0.179 2433942.0, 3491573.0 -0.02
CXB3/ByJ m 3516871.0 249021.0   2   176084.0 0.0708 3340787.0, 3692956.0 0.18
CXB4/ByJ m 2381278.0 574572.0   2   406284.0 0.241 1974994.0, 2787562.0 -0.28
CXB6/ByJ m 3047532.0 345633.0   3 199551.0 0.113 2714216.0, 3404288.0 -0.01
CXB7/ByJ m 3200966.0 441196.0   2   311972.0 0.138 2888993.0, 3512938.0 0.05
CXB8/HiAJ m 2876161.0 281391.0   3 162461.0 0.0978 2552123.0, 3058925.0 -0.08
CXB9/HiAJ m 2093812.0 700570.0   3 404474.0 0.335 1320835.0, 2686886.0 -0.4
DBA/2J m 6120614.0 792070.0   4 396035.0 0.129 5011544.0, 6885222.0 1.25
FVB/NJ m 2441402.0 0.0   1   0.0 0.0 2441402.0, 2441402.0 -0.26
I/LnJ m 1733132.0 0.0   1   0.0 0.0 1733132.0, 1733132.0 -0.55
KK/HlJ m 1923361.0 0.0   1   0.0 0.0 1923361.0, 1923361.0 -0.47
LG/J m 1528600.0 0.0   1   0.0 0.0 1528600.0, 1528600.0 -0.63
LP/J m 2131250.0 0.0   1   0.0 0.0 2131250.0, 2131250.0 -0.38
MA/MyJ m 2865618.0 0.0   1   0.0 0.0 2865618.0, 2865618.0 -0.08
NOD/ShiLtJ m 2250535.0 0.0   1   0.0 0.0 2250535.0, 2250535.0 -0.34
NON/ShiLtJ m 2331384.0 0.0   1   0.0 0.0 2331384.0, 2331384.0 -0.3
NZW/LacJ m 1705068.0 0.0   1   0.0 0.0 1705068.0, 1705068.0 -0.56
PL/J m 1662639.0 0.0   1   0.0 0.0 1662639.0, 1662639.0 -0.58
RIIIS/J m 2240698.0 0.0   1   0.0 0.0 2240698.0, 2240698.0 -0.34
SEA/GnJ m 3066859.0 0.0   1   0.0 0.0 3066859.0, 3066859.0 0.0
SJL/J m 2041352.0 0.0   1   0.0 0.0 2041352.0, 2041352.0 -0.42
SM/J m 12311601.0 0.0   1   0.0 0.0 12311601.0, 12311601.0 3.78
SWR/J m 2911010.0 0.0   1   0.0 0.0 2911010.0, 2911010.0 -0.07


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 1882052.15 710002.9433 3324951.7331 439152.5669
AXB19b/PgnJ m 2842095.15 710002.9433 4284994.7331 1399195.5669
AXB24/PgnJ m 1308403.7 710002.9433 2751303.2831 0.0
BALB/cJ m 3593383.6 579714.9756 4771506.1762 2415261.0238
BXA16/PgnJ m 4518150.9 710002.9433 5961050.4831 3075251.3169
BXD19/TyJ m 4921914.5 710002.9433 6364814.0831 3479014.9169
BXD28/TyJ m 1740474.7 710002.9433 3183374.2831 297575.1169
BXH4/TyJ m 2058508.2 710002.9433 3501407.7831 615608.6169
C3H/HeJ m 2189278.35 710002.9433 3632177.9331 746378.7669
C57BL/6J m 2713194.92 449045.2892 3625764.7435 1800625.0965
CXB11/HiAJ m 1978871.3 710002.9433 3421770.8831 535971.7169
CXB12/HiAJ m 2775709.4 710002.9433 4218608.9831 1332809.8169
CXB13/HiAJ m 2594802.5 579714.9756 3772925.0762 1416679.9238
CXB1/ByJ m 2417507.8667 579714.9756 3595630.4429 1239385.2905
CXB2/ByJ m 3030907.6 579714.9756 4209030.1762 1852785.0238
CXB3/ByJ m 3516871.4 710002.9433 4959770.9831 2073971.8169
CXB4/ByJ m 2381278.5 710002.9433 3824178.0831 938378.9169
CXB6/ByJ m 3047532.1 579714.9756 4225654.6762 1869409.5238
CXB7/ByJ m 3200965.65 710002.9433 4643865.2331 1758066.0669
CXB8/HiAJ m 2876160.9667 579714.9756 4054283.5429 1698038.3905
CXB9/HiAJ m 2093811.6333 579714.9756 3271934.2095 915689.0571
DBA/2J m 6120613.625 502047.8959 7140897.7048 5100329.5452




  GWAS USING LINEAR MIXED MODELS