Project measure / variable:   Rusyn5   liver_GSSG_hfe

ID, description, units MPD:43026   liver_GSSG_hfe   oxidized liver glutathione (GSSG)   [nmol/mg]  high-fat and ethanol  
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure metabolite quantification
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  STRAIN COMPARISON PLOT
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Rusyn5 - oxidized liver glutathione (GSSG) high-fat and ethanol



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means2.16   nmol/mg
Median of the strain means2.05   nmol/mg
SD of the strain means± 0.396
Coefficient of variation (CV)0.183
Min–max range of strain means1.71   –   2.97   nmol/mg
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 6.1442 0.4726 1.5268 0.1711
Residuals 27 8.3581 0.3096


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 1.71 0.511   3 0.295 0.299 1.27, 2.27 -1.13
AKR/J m 2.57 0.44   3 0.254 0.172 2.07, 2.91 1.04
BALB/cByJ m 2.97 0.777   3 0.449 0.261 2.5, 3.87 2.05
BALB/cJ m 2.38 0.491   3 0.283 0.207 1.83, 2.78 0.56
BTBR T+ Itpr3tf/J m 2.28 0.542   3 0.313 0.238 1.76, 2.84 0.3
C3H/HeJ m 1.92 0.305   3 0.176 0.159 1.61, 2.22 -0.6
C57BL/10J m 1.95 1.11   3 0.639 0.569 1.04, 3.18 -0.53
DBA/2J m 2.15 0.616   3 0.356 0.286 1.76, 2.86 -0.02
FVB/NJ m 1.77 0.647   3 0.373 0.366 1.02, 2.14 -0.98
KK/HlJ m 1.96 0.518   3 0.299 0.265 1.36, 2.29 -0.5
MOLF/EiJ m 1.79 0.106   3 0.0612 0.0591 1.68, 1.89 -0.93
NZW/LacJ m 1.83 0.271   3 0.156 0.148 1.52, 2.02 -0.83
PWD/PhJ m 2.15 0.311   2   0.22 0.145 1.93, 2.37 -0.02
WSB/EiJ m 2.8 0.264   3 0.152 0.0942 2.57, 3.09 1.62


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 1.71 0.3212 2.3691 1.0509
AKR/J m 2.5667 0.3212 3.2258 1.9076
BALB/cByJ m 2.9733 0.3212 3.6324 2.3142
BALB/cJ m 2.3767 0.3212 3.0358 1.7176
BTBR T+ Itpr3tf/J m 2.2767 0.3212 2.9358 1.6176
C3H/HeJ m 1.9167 0.3212 2.5758 1.2576
C57BL/10J m 1.9467 0.3212 2.6058 1.2876
DBA/2J m 2.15 0.3212 2.8091 1.4909
FVB/NJ m 1.7667 0.3212 2.4258 1.1076
KK/HlJ m 1.9567 0.3212 2.6158 1.2976
MOLF/EiJ m 1.7933 0.3212 2.4524 1.1342
NZW/LacJ m 1.83 0.3212 2.4891 1.1709
PWD/PhJ m 2.15 0.3934 2.9572 1.3428
WSB/EiJ m 2.8033 0.3212 3.4624 2.1442




  GWAS USING LINEAR MIXED MODELS