Project measure / variable:   Rusyn5   liver_GSSG_hf

ID, description, units MPD:43025   liver_GSSG_hf   oxidized liver glutathione (GSSG)   [nmol/mg]  high-fat only  
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Rusyn5 - oxidized liver glutathione (GSSG) high-fat only



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means1.77   nmol/mg
Median of the strain means1.62   nmol/mg
SD of the strain means± 0.486
Coefficient of variation (CV)0.274
Min–max range of strain means1.20   –   2.89   nmol/mg
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 9.2192 0.7092 3.2384 0.0044
Residuals 28 6.1317 0.219


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 2.89 1.26   3 0.725 0.434 1.66, 4.17 2.29
AKR/J m 2.35 0.44   3 0.254 0.188 1.95, 2.82 1.18
BALB/cByJ m 2.34 0.254   3 0.146 0.108 2.05, 2.52 1.16
BALB/cJ m 1.82 0.501   3 0.29 0.275 1.49, 2.4 0.09
BTBR T+ Itpr3tf/J m 1.52 0.19   3 0.11 0.126 1.32, 1.7 -0.52
C3H/HeJ m 1.66 0.281   3 0.162 0.169 1.37, 1.93 -0.24
C57BL/10J m 1.2 0.16   3 0.0924 0.133 1.04, 1.36 -1.18
DBA/2J m 1.34 0.0624   3 0.0361 0.0466 1.29, 1.41 -0.89
FVB/NJ m 1.5 0.465   3 0.268 0.31 0.99, 1.9 -0.56
KK/HlJ m 1.66 0.267   3 0.154 0.16 1.38, 1.91 -0.24
MOLF/EiJ m 1.58 0.311   3 0.179 0.197 1.22, 1.79 -0.4
NZW/LacJ m 1.46 0.284   3 0.164 0.194 1.21, 1.77 -0.65
PWD/PhJ m 1.34 0.11   3 0.0636 0.0824 1.21, 1.41 -0.89
WSB/EiJ m 2.18 0.599   3 0.346 0.275 1.51, 2.67 0.83


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 2.8933 0.2702 3.4468 2.3399
AKR/J m 2.3467 0.2702 2.9001 1.7932
BALB/cByJ m 2.34 0.2702 2.8934 1.7866
BALB/cJ m 1.8233 0.2702 2.3768 1.2699
BTBR T+ Itpr3tf/J m 1.5167 0.2702 2.0701 0.9632
C3H/HeJ m 1.66 0.2702 2.2134 1.1066
C57BL/10J m 1.2033 0.2702 1.7568 0.6499
DBA/2J m 1.34 0.2702 1.8934 0.7866
FVB/NJ m 1.5 0.2702 2.0534 0.9466
KK/HlJ m 1.6633 0.2702 2.2168 1.1099
MOLF/EiJ m 1.5767 0.2702 2.1301 1.0232
NZW/LacJ m 1.4633 0.2702 2.0168 0.9099
PWD/PhJ m 1.3367 0.2702 1.8901 0.7832
WSB/EiJ m 2.1767 0.2702 2.7301 1.6232




  GWAS USING LINEAR MIXED MODELS