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Project measure / variable:   Harrill1   microvesic_dif_trt

ID, description, units MPD:39552   microvesic_dif_trt   hepatocytic cytoplasmic, microvesiculation, diffuse   [score]  isoniazid  
isoniazid study
Data set, strains Harrill1   inbred   34 strains     sex: f     age: 8-10wks
Procedure histopathology
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  STRAIN COMPARISON PLOT
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Harrill1 - hepatocytic cytoplasmic, microvesiculation, diffuse isoniazid



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested34 strains
Mean of the strain means2.28   score
Median of the strain means2.25   score
SD of the strain means± 1.07
Coefficient of variation (CV)0.468
Min–max range of strain means0   –   4.67   score
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 143.6169 4.352 5.11 < 0.0001
Residuals 100 85.1667 0.8517


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.5 0.577   4 0.289 0.231 2.0, 3.0 0.2
A/J f 3.0 0.816   4 0.408 0.272 2.0, 4.0 0.67
AKR/J f 2.75 1.26   4 0.629 0.458 1.0, 4.0 0.44
BALB/cJ f 0.0 0.0   4 0.0 0.0 -2.14
BTBR T+ Itpr3tf/J f 3.0 0.0   4 0.0 0.0 3.0, 3.0 0.67
BUB/BnJ f 3.0 0.0   4 0.0 0.0 3.0, 3.0 0.67
C3H/HeJ f 1.75 1.26   4 0.629 0.719 -0.5
C57BL/6J f 2.0 0.816   4 0.408 0.408 1.0, 3.0 -0.27
C57BLKS/J f 2.25 0.5   4 0.25 0.222 2.0, 3.0 -0.03
C57BR/cdJ f 1.0 2.0   4 1.0 2.0 -1.2
C58/J f 2.0 1.41   4 0.707 0.707 -0.27
CBA/J f 2.5 0.577   4 0.289 0.231 2.0, 3.0 0.2
CE/J f 3.25 0.5   4 0.25 0.154 3.0, 4.0 0.9
DBA/2J f 3.25 0.5   4 0.25 0.154 3.0, 4.0 0.9
FVB/NJ f 3.25 0.5   4 0.25 0.154 3.0, 4.0 0.9
I/LnJ f 1.25 0.5   4 0.25 0.4 1.0, 2.0 -0.97
KK/HlJ f 1.5 0.577   4 0.289 0.385 1.0, 2.0 -0.73
LG/J f 4.67 0.577   3 0.333 0.124 4.0, 5.0 2.23
LP/J f 1.5 1.0   4 0.5 0.667 1.0, 3.0 -0.73
MA/MyJ f 3.75 0.5   4 0.25 0.133 3.0, 4.0 1.37
MRL/MpJ f 1.75 0.5   4 0.25 0.286 1.0, 2.0 -0.5
NOD/ShiLtJ f 2.0 1.41   4 0.707 0.707 -0.27
NON/ShiLtJ f 0.75 0.5   4 0.25 0.667 -1.43
NOR/LtJ f 2.5 0.577   4 0.289 0.231 2.0, 3.0 0.2
NZW/LacJ f 4.0 0.0   4 0.0 0.0 4.0, 4.0 1.6
P/J f 2.0 1.41   4 0.707 0.707 -0.27
PL/J f 2.0 0.816   4 0.408 0.408 1.0, 3.0 -0.27
PWK/PhJ f 1.0 0.816   4 0.408 0.816 -1.2
RIIIS/J f 0.75 1.5   4 0.75 2.0 -1.43
SEA/GnJ f 2.75 0.5   4 0.25 0.182 2.0, 3.0 0.44
SJL/J f 2.5 0.577   4 0.289 0.231 2.0, 3.0 0.2
SM/J f 4.25 0.957   4 0.479 0.225 3.0, 5.0 1.84
SWR/J f 2.25 1.5   4 0.75 0.667 -0.03
WSB/EiJ f 1.0 1.73   3 1.0 1.73 -1.2


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.5 0.4614 3.4155 1.5845
A/J f 3.0 0.4614 3.9155 2.0845
AKR/J f 2.75 0.4614 3.6655 1.8345
BALB/cJ f 0.0 0.4614 0.9155 -0.9155
BTBR T+ Itpr3tf/J f 3.0 0.4614 3.9155 2.0845
BUB/BnJ f 3.0 0.4614 3.9155 2.0845
C3H/HeJ f 1.75 0.4614 2.6655 0.8345
C57BL/6J f 2.0 0.4614 2.9155 1.0845
C57BLKS/J f 2.25 0.4614 3.1655 1.3345
C57BR/cdJ f 1.0 0.4614 1.9155 0.0845
C58/J f 2.0 0.4614 2.9155 1.0845
CBA/J f 2.5 0.4614 3.4155 1.5845
CE/J f 3.25 0.4614 4.1655 2.3345
DBA/2J f 3.25 0.4614 4.1655 2.3345
FVB/NJ f 3.25 0.4614 4.1655 2.3345
I/LnJ f 1.25 0.4614 2.1655 0.3345
KK/HlJ f 1.5 0.4614 2.4155 0.5845
LG/J f 4.6667 0.5328 5.7238 3.6096
LP/J f 1.5 0.4614 2.4155 0.5845
MA/MyJ f 3.75 0.4614 4.6655 2.8345
MRL/MpJ f 1.75 0.4614 2.6655 0.8345
NOD/ShiLtJ f 2.0 0.4614 2.9155 1.0845
NON/ShiLtJ f 0.75 0.4614 1.6655 -0.1655
NOR/LtJ f 2.5 0.4614 3.4155 1.5845
NZW/LacJ f 4.0 0.4614 4.9155 3.0845
P/J f 2.0 0.4614 2.9155 1.0845
PL/J f 2.0 0.4614 2.9155 1.0845
PWK/PhJ f 1.0 0.4614 1.9155 0.0845
RIIIS/J f 0.75 0.4614 1.6655 -0.1655
SEA/GnJ f 2.75 0.4614 3.6655 1.8345
SJL/J f 2.5 0.4614 3.4155 1.5845
SM/J f 4.25 0.4614 5.1655 3.3345
SWR/J f 2.25 0.4614 3.1655 1.3345
WSB/EiJ f 1.0 0.5328 2.0571 -0.0571




  GWAS USING LINEAR MIXED MODELS