Project measure / variable:   Berndt2   airway_res_slope

ID, description, units MPD:35186   airway_res_slope   airway resistance (H20 pressure)   [cm/mL/s]  response index  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure ventilator
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - airway resistance (H20 pressure) response index



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.351   cm/mL/s 0.398   cm/mL/s
Median of the strain means0.335   cm/mL/s 0.395   cm/mL/s
SD of the strain means± 0.0759 ± 0.0835
Coefficient of variation (CV)0.216 0.210
Min–max range of strain means0.191   –   0.532   cm/mL/s 0.247   –   0.611   cm/mL/s
Mean sample size per strain8.7   mice 9.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.3288 0.3288 31.6773 < 0.0001
strain 28 2.6173 0.0935 9.0062 < 0.0001
sex:strain 28 0.596 0.0213 2.0508 0.0014
Residuals 462 4.795 0.0104


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.335 0.0729   9 0.0243 0.217 0.238, 0.469 -0.21
129S1/SvImJ m 0.381 0.15   8 0.0529 0.393 0.164, 0.531 -0.2
A/J f 0.393 0.0889   10 0.0281 0.226 0.227, 0.5 0.55
A/J m 0.36 0.146   9 0.0488 0.406 0.202, 0.603 -0.46
AKR/J f 0.319 0.0954   9 0.0318 0.299 0.205, 0.496 -0.42
AKR/J m 0.261 0.0988   8 0.0349 0.379 0.146, 0.476 -1.64
BALB/cByJ f 0.316 0.111   8 0.0393 0.351 0.227, 0.57 -0.46
BALB/cByJ m 0.362 0.077   8 0.0272 0.213 0.23, 0.46 -0.43
BALB/cJ f 0.284 0.0921   8 0.0326 0.324 0.1, 0.407 -0.88
BALB/cJ m 0.395 0.0884   10 0.0279 0.224 0.274, 0.534 -0.04
BTBR T+ Itpr3tf/J f 0.4 0.147   10 0.0464 0.367 0.249, 0.762 0.65
BTBR T+ Itpr3tf/J m 0.433 0.0896   10 0.0283 0.207 0.291, 0.548 0.42
BUB/BnJ f 0.317 0.0913   9 0.0304 0.287 0.218, 0.478 -0.45
BUB/BnJ m 0.429 0.145   10 0.0458 0.338 0.226, 0.682 0.37
C3H/HeJ f 0.293 0.0906   10 0.0287 0.309 0.1, 0.399 -0.76
C3H/HeJ m 0.303 0.109   9 0.0363 0.36 0.106, 0.466 -1.14
C57BL/10J f 0.346 0.0576   9 0.0192 0.167 0.259, 0.42 -0.06
C57BL/10J m 0.458 0.0535   10 0.0169 0.117 0.38, 0.551 0.72
C57BL/6J f 0.191 0.0326   8 0.0115 0.171 0.155, 0.243 -2.11
C57BL/6J m 0.247 0.123   8 0.0436 0.499 0.037, 0.413 -1.81
C57BLKS/J f 0.497 0.126   9 0.0421 0.254 0.309, 0.663 1.93
C57BLKS/J m 0.545 0.0911   12 0.0263 0.167 0.323, 0.661 1.76
C57BR/cdJ f 0.347 0.143   7 0.0541 0.413 0.171, 0.537 -0.05
C57BR/cdJ m 0.41 0.114   10 0.036 0.277 0.27, 0.617 0.14
C57L/J f 0.442 0.0566   6 0.0231 0.128 0.351, 0.497 1.2
C57L/J m 0.375 0.0756   10 0.0239 0.202 0.276, 0.512 -0.28
CBA/J f 0.249 0.0857   8 0.0303 0.344 0.143, 0.41 -1.34
CBA/J m 0.368 0.0849   10 0.0269 0.231 0.244, 0.514 -0.36
CE/J f 0.396 0.143   9 0.0477 0.362 0.095, 0.569 0.59
CE/J m 0.399 0.0584   9 0.0195 0.146 0.315, 0.489 0.01
DBA/1J f 0.432 0.104   9 0.0346 0.24 0.28, 0.576 1.07
DBA/1J m 0.468 0.127   10 0.0402 0.272 0.333, 0.681 0.84
DBA/2J f 0.416 0.106   10 0.0336 0.256 0.261, 0.597 0.86
DBA/2J m 0.394 0.0754   10 0.0238 0.191 0.252, 0.505 -0.05
FVB/NJ f 0.328 0.0814   10 0.0258 0.249 0.162, 0.436 -0.3
FVB/NJ m 0.492 0.0816   10 0.0258 0.166 0.382, 0.649 1.13
I/LnJ f 0.425 0.142   9 0.0474 0.334 0.247, 0.676 0.98
I/LnJ m 0.421 0.0847   8 0.0299 0.201 0.281, 0.513 0.28
KK/HlJ f 0.532 0.115   9 0.0384 0.217 0.371, 0.748 2.39
KK/HlJ m 0.611 0.111   10 0.035 0.181 0.456, 0.805 2.55
LP/J f 0.372 0.072   9 0.024 0.193 0.274, 0.473 0.28
LP/J m 0.532 0.072   10 0.0228 0.135 0.414, 0.657 1.6
NOD/ShiLtJ f 0.386 0.115   9 0.0384 0.299 0.113, 0.494 0.46
NOD/ShiLtJ m 0.397 0.123   9 0.0409 0.309 0.11, 0.526 -0.01
NON/ShiLtJ f 0.294 0.0681   7 0.0257 0.232 0.204, 0.389 -0.75
NON/ShiLtJ m 0.371 0.136   7 0.0515 0.368 0.097, 0.532 -0.32
NZW/LacJ f 0.361 0.113   8 0.0401 0.315 0.203, 0.514 0.13
NZW/LacJ m 0.416 0.136   10 0.0429 0.325 0.256, 0.673 0.22
PL/J f 0.331 0.0903   9 0.0301 0.272 0.213, 0.481 -0.26
PL/J m 0.338 0.0954   8 0.0337 0.282 0.192, 0.46 -0.72
RIIIS/J f 0.297 0.124   6 0.0506 0.417 0.123, 0.407 -0.71
RIIIS/J m 0.25 0.0771   9 0.0257 0.309 0.171, 0.389 -1.77
SJL/J f 0.212 0.0694   8 0.0245 0.327 0.086, 0.305 -1.83
SJL/J m 0.442 0.0993   9 0.0331 0.225 0.206, 0.533 0.53
SM/J f 0.334 0.0671   10 0.0212 0.201 0.224, 0.44 -0.22
SM/J m 0.353 0.0648   8 0.0229 0.184 0.244, 0.434 -0.54
SWR/J f 0.332 0.0602   9 0.0201 0.182 0.253, 0.434 -0.25
SWR/J m 0.332 0.133   10 0.0419 0.399 0.182, 0.655 -0.79


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.3354 0.034 0.4022 0.2687
129S1/SvImJ m 0.3809 0.036 0.4517 0.3101
A/J f 0.3926 0.0322 0.4559 0.3293
A/J m 0.36 0.034 0.4267 0.2933
AKR/J f 0.3193 0.034 0.3861 0.2526
AKR/J m 0.2607 0.036 0.3315 0.19
BALB/cByJ f 0.3164 0.036 0.3872 0.2456
BALB/cByJ m 0.3616 0.036 0.4324 0.2908
BALB/cJ f 0.2844 0.036 0.3552 0.2136
BALB/cJ m 0.3954 0.0322 0.4587 0.3321
BTBR T+ Itpr3tf/J f 0.4005 0.0322 0.4638 0.3372
BTBR T+ Itpr3tf/J m 0.4335 0.0322 0.4968 0.3702
BUB/BnJ f 0.3174 0.034 0.3842 0.2507
BUB/BnJ m 0.4289 0.0322 0.4922 0.3656
C3H/HeJ f 0.293 0.0322 0.3563 0.2297
C3H/HeJ m 0.3029 0.034 0.3696 0.2362
C57BL/10J f 0.3458 0.034 0.4125 0.279
C57BL/10J m 0.4583 0.0322 0.5216 0.395
C57BL/6J f 0.1909 0.036 0.2617 0.1201
C57BL/6J m 0.2471 0.036 0.3179 0.1763
C57BLKS/J f 0.497 0.034 0.5637 0.4303
C57BLKS/J m 0.5448 0.0294 0.6025 0.487
C57BR/cdJ f 0.3466 0.0385 0.4222 0.2709
C57BR/cdJ m 0.41 0.0322 0.4733 0.3467
C57L/J f 0.4415 0.0416 0.5232 0.3598
C57L/J m 0.3746 0.0322 0.4379 0.3113
CBA/J f 0.2488 0.036 0.3195 0.178
CBA/J m 0.3676 0.0322 0.4309 0.3043
CE/J f 0.3956 0.034 0.4623 0.3288
CE/J m 0.3994 0.034 0.4662 0.3327
DBA/1J f 0.4324 0.034 0.4992 0.3657
DBA/1J m 0.4684 0.0322 0.5317 0.4051
DBA/2J f 0.416 0.0322 0.4793 0.3527
DBA/2J m 0.394 0.0322 0.4573 0.3307
FVB/NJ f 0.3277 0.0322 0.391 0.2644
FVB/NJ m 0.4917 0.0322 0.555 0.4284
I/LnJ f 0.425 0.034 0.4917 0.3583
I/LnJ m 0.4206 0.036 0.4914 0.3498
KK/HlJ f 0.5321 0.034 0.5988 0.4654
KK/HlJ m 0.6112 0.0322 0.6745 0.5479
LP/J f 0.3724 0.034 0.4392 0.3057
LP/J m 0.5321 0.0322 0.5954 0.4688
NOD/ShiLtJ f 0.3856 0.034 0.4523 0.3188
NOD/ShiLtJ m 0.3973 0.034 0.4641 0.3306
NON/ShiLtJ f 0.2939 0.0385 0.3695 0.2182
NON/ShiLtJ m 0.3709 0.0385 0.4465 0.2952
NZW/LacJ f 0.3605 0.036 0.4313 0.2897
NZW/LacJ m 0.4165 0.0322 0.4798 0.3532
PL/J f 0.3314 0.034 0.3982 0.2647
PL/J m 0.3384 0.036 0.4092 0.2676
RIIIS/J f 0.2968 0.0416 0.3786 0.2151
RIIIS/J m 0.2499 0.034 0.3166 0.1832
SJL/J f 0.212 0.036 0.2828 0.1412
SJL/J m 0.4418 0.034 0.5085 0.375
SM/J f 0.334 0.0322 0.3973 0.2707
SM/J m 0.3528 0.036 0.4235 0.282
SWR/J f 0.3317 0.034 0.3984 0.2649
SWR/J m 0.3324 0.0322 0.3957 0.2691


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.3582 0.0248 0.4068 0.3095
A/J both 0.3763 0.0234 0.4223 0.3303
AKR/J both 0.29 0.0248 0.3387 0.2414
BALB/cByJ both 0.339 0.0255 0.389 0.289
BALB/cJ both 0.3399 0.0242 0.3874 0.2924
BTBR T+ Itpr3tf/J both 0.417 0.0228 0.4618 0.3722
BUB/BnJ both 0.3732 0.0234 0.4192 0.3272
C3H/HeJ both 0.2979 0.0234 0.3439 0.252
C57BL/10J both 0.402 0.0234 0.448 0.356
C57BL/6J both 0.219 0.0255 0.269 0.169
C57BLKS/J both 0.5209 0.0225 0.565 0.4767
C57BR/cdJ both 0.3783 0.0251 0.4276 0.329
C57L/J both 0.4081 0.0263 0.4597 0.3564
CBA/J both 0.3082 0.0242 0.3557 0.2607
CE/J both 0.3975 0.024 0.4447 0.3503
DBA/1J both 0.4504 0.0234 0.4964 0.4044
DBA/2J both 0.405 0.0228 0.4498 0.3602
FVB/NJ both 0.4097 0.0228 0.4545 0.3649
I/LnJ both 0.4228 0.0248 0.4715 0.3742
KK/HlJ both 0.5717 0.0234 0.6176 0.5257
LP/J both 0.4523 0.0234 0.4983 0.4063
NOD/ShiLtJ both 0.3914 0.024 0.4386 0.3443
NON/ShiLtJ both 0.3324 0.0272 0.3859 0.2789
NZW/LacJ both 0.3885 0.0242 0.436 0.341
PL/J both 0.3349 0.0248 0.3835 0.2863
RIIIS/J both 0.2734 0.0268 0.3261 0.2206
SJL/J both 0.3269 0.0248 0.3755 0.2782
SM/J both 0.3434 0.0242 0.3909 0.2959
SWR/J both 0.332 0.0234 0.378 0.286




  GWAS USING LINEAR MIXED MODELS