Project measure / variable:   Berndt2   airway_res_mch1

ID, description, units MPD:35182   airway_res_mch1   airway resistance (H20 pressure)   [cm/mL/s]  1 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure ventilator
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  STRAIN COMPARISON PLOT
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Berndt2 - airway resistance (H20 pressure) 1 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.503   cm/mL/s 0.540   cm/mL/s
Median of the strain means0.535   cm/mL/s 0.544   cm/mL/s
SD of the strain means± 0.134 ± 0.133
Coefficient of variation (CV)0.267 0.246
Min–max range of strain means0.283   –   0.751   cm/mL/s 0.333   –   0.889   cm/mL/s
Mean sample size per strain8.7   mice 9.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1348 0.1348 7.0402 0.0082
strain 28 6.5982 0.2356 12.3099 < 0.0001
sex:strain 28 2.0761 0.0741 3.8733 < 0.0001
Residuals 462 8.8441 0.0191


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.283 0.0339   9 0.0113 0.12 0.24, 0.33 -1.64
129S1/SvImJ m 0.333 0.0907   8 0.0321 0.273 0.21, 0.5 -1.56
A/J f 0.585 0.159   10 0.0503 0.272 0.4, 0.85 0.61
A/J m 0.794 0.17   9 0.0567 0.214 0.54, 1.03 1.91
AKR/J f 0.573 0.144   9 0.0482 0.252 0.32, 0.79 0.52
AKR/J m 0.889 0.269   8 0.0952 0.303 0.51, 1.35 2.63
BALB/cByJ f 0.506 0.107   8 0.0379 0.212 0.4, 0.73 0.02
BALB/cByJ m 0.645 0.19   8 0.067 0.294 0.42, 0.93 0.79
BALB/cJ f 0.606 0.254   8 0.0898 0.419 0.43, 1.21 0.77
BALB/cJ m 0.629 0.114   10 0.0359 0.181 0.43, 0.79 0.67
BTBR T+ Itpr3tf/J f 0.535 0.161   10 0.051 0.301 0.31, 0.78 0.24
BTBR T+ Itpr3tf/J m 0.508 0.111   10 0.0352 0.219 0.4, 0.78 -0.24
BUB/BnJ f 0.751 0.177   9 0.0589 0.235 0.52, 1.1 1.85
BUB/BnJ m 0.565 0.127   10 0.04 0.224 0.42, 0.81 0.19
C3H/HeJ f 0.638 0.176   10 0.0557 0.276 0.43, 0.94 1.01
C3H/HeJ m 0.647 0.173   9 0.0578 0.268 0.47, 1.02 0.81
C57BL/10J f 0.309 0.0404   9 0.0135 0.131 0.27, 0.41 -1.45
C57BL/10J m 0.387 0.0462   10 0.0146 0.119 0.3, 0.43 -1.15
C57BL/6J f 0.354 0.0847   8 0.0299 0.239 0.25, 0.46 -1.11
C57BL/6J m 0.621 0.209   8 0.0737 0.336 0.36, 1.04 0.61
C57BLKS/J f 0.3 0.0522   9 0.0174 0.174 0.22, 0.37 -1.51
C57BLKS/J m 0.403 0.096   12 0.0277 0.238 0.27, 0.55 -1.03
C57BR/cdJ f 0.531 0.172   7 0.0652 0.324 0.31, 0.71 0.21
C57BR/cdJ m 0.457 0.0897   10 0.0284 0.196 0.36, 0.62 -0.63
C57L/J f 0.482 0.165   6 0.0672 0.342 0.26, 0.67 -0.15
C57L/J m 0.435 0.0752   10 0.0238 0.173 0.29, 0.58 -0.79
CBA/J f 0.661 0.106   8 0.0376 0.161 0.52, 0.85 1.18
CBA/J m 0.522 0.0794   10 0.0251 0.152 0.43, 0.65 -0.14
CE/J f 0.544 0.168   9 0.0559 0.308 0.36, 0.86 0.31
CE/J m 0.594 0.104   9 0.0348 0.175 0.43, 0.74 0.41
DBA/1J f 0.556 0.153   9 0.0511 0.276 0.35, 0.87 0.4
DBA/1J m 0.494 0.102   10 0.0323 0.206 0.33, 0.68 -0.35
DBA/2J f 0.411 0.0703   10 0.0222 0.171 0.31, 0.54 -0.68
DBA/2J m 0.557 0.0615   10 0.0194 0.11 0.48, 0.63 0.13
FVB/NJ f 0.567 0.161   10 0.051 0.284 0.27, 0.88 0.48
FVB/NJ m 0.431 0.198   10 0.0625 0.459 0.18, 0.77 -0.82
I/LnJ f 0.617 0.104   9 0.0348 0.169 0.42, 0.74 0.85
I/LnJ m 0.586 0.0962   8 0.034 0.164 0.44, 0.71 0.35
KK/HlJ f 0.537 0.122   9 0.0408 0.228 0.38, 0.72 0.26
KK/HlJ m 0.496 0.0412   10 0.013 0.083 0.44, 0.57 -0.33
LP/J f 0.297 0.04   9 0.0133 0.135 0.23, 0.34 -1.53
LP/J m 0.388 0.0449   10 0.0142 0.116 0.33, 0.46 -1.15
NOD/ShiLtJ f 0.421 0.152   9 0.0508 0.362 0.25, 0.77 -0.61
NOD/ShiLtJ m 0.621 0.118   9 0.0395 0.191 0.43, 0.79 0.61
NON/ShiLtJ f 0.677 0.207   7 0.0781 0.305 0.49, 0.98 1.3
NON/ShiLtJ m 0.6 0.271   7 0.102 0.451 0.42, 1.19 0.45
NZW/LacJ f 0.368 0.0819   8 0.029 0.223 0.25, 0.51 -1.0
NZW/LacJ m 0.346 0.0566   10 0.0179 0.164 0.26, 0.45 -1.46
PL/J f 0.491 0.137   9 0.0458 0.28 0.3, 0.68 -0.09
PL/J m 0.749 0.115   8 0.0408 0.154 0.61, 0.99 1.57
RIIIS/J f 0.718 0.389   6 0.159 0.541 0.34, 1.4 1.61
RIIIS/J m 0.571 0.171   9 0.0569 0.299 0.33, 0.91 0.23
SJL/J f 0.409 0.113   8 0.0401 0.278 0.32, 0.67 -0.7
SJL/J m 0.454 0.0847   9 0.0282 0.186 0.33, 0.57 -0.65
SM/J f 0.543 0.143   10 0.0451 0.262 0.42, 0.86 0.3
SM/J m 0.544 0.0737   8 0.026 0.135 0.41, 0.64 0.03
SWR/J f 0.307 0.0602   9 0.0201 0.196 0.23, 0.41 -1.46
SWR/J m 0.396 0.118   10 0.0373 0.298 0.3, 0.69 -1.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.2833 0.0461 0.374 0.1927
129S1/SvImJ m 0.3325 0.0489 0.4286 0.2364
A/J f 0.585 0.0438 0.671 0.499
A/J m 0.7944 0.0461 0.8851 0.7038
AKR/J f 0.5733 0.0461 0.664 0.4827
AKR/J m 0.8888 0.0489 0.9849 0.7926
BALB/cByJ f 0.5062 0.0489 0.6024 0.4101
BALB/cByJ m 0.645 0.0489 0.7411 0.5489
BALB/cJ f 0.6062 0.0489 0.7024 0.5101
BALB/cJ m 0.629 0.0438 0.715 0.543
BTBR T+ Itpr3tf/J f 0.535 0.0438 0.621 0.449
BTBR T+ Itpr3tf/J m 0.508 0.0438 0.594 0.422
BUB/BnJ f 0.7511 0.0461 0.8417 0.6605
BUB/BnJ m 0.565 0.0438 0.651 0.479
C3H/HeJ f 0.638 0.0438 0.724 0.552
C3H/HeJ m 0.6467 0.0461 0.7373 0.556
C57BL/10J f 0.3089 0.0461 0.3995 0.2183
C57BL/10J m 0.387 0.0438 0.473 0.301
C57BL/6J f 0.3538 0.0489 0.4499 0.2576
C57BL/6J m 0.6213 0.0489 0.7174 0.5251
C57BLKS/J f 0.3 0.0461 0.3906 0.2094
C57BLKS/J m 0.4033 0.0399 0.4818 0.3248
C57BR/cdJ f 0.5314 0.0523 0.6342 0.4287
C57BR/cdJ m 0.457 0.0438 0.543 0.371
C57L/J f 0.4817 0.0565 0.5927 0.3707
C57L/J m 0.435 0.0438 0.521 0.349
CBA/J f 0.6613 0.0489 0.7574 0.5651
CBA/J m 0.522 0.0438 0.608 0.436
CE/J f 0.5444 0.0461 0.6351 0.4538
CE/J m 0.5944 0.0461 0.6851 0.5038
DBA/1J f 0.5556 0.0461 0.6462 0.4649
DBA/1J m 0.494 0.0438 0.58 0.408
DBA/2J f 0.411 0.0438 0.497 0.325
DBA/2J m 0.557 0.0438 0.643 0.471
FVB/NJ f 0.567 0.0438 0.653 0.481
FVB/NJ m 0.431 0.0438 0.517 0.345
I/LnJ f 0.6167 0.0461 0.7073 0.526
I/LnJ m 0.5862 0.0489 0.6824 0.4901
KK/HlJ f 0.5367 0.0461 0.6273 0.446
KK/HlJ m 0.496 0.0438 0.582 0.41
LP/J f 0.2967 0.0461 0.3873 0.206
LP/J m 0.388 0.0438 0.474 0.302
NOD/ShiLtJ f 0.4211 0.0461 0.5117 0.3305
NOD/ShiLtJ m 0.6211 0.0461 0.7117 0.5305
NON/ShiLtJ f 0.6771 0.0523 0.7799 0.5744
NON/ShiLtJ m 0.6 0.0523 0.7028 0.4972
NZW/LacJ f 0.3675 0.0489 0.4636 0.2714
NZW/LacJ m 0.346 0.0438 0.432 0.26
PL/J f 0.4911 0.0461 0.5817 0.4005
PL/J m 0.7487 0.0489 0.8449 0.6526
RIIIS/J f 0.7183 0.0565 0.8293 0.6073
RIIIS/J m 0.5711 0.0461 0.6617 0.4805
SJL/J f 0.4088 0.0489 0.5049 0.3126
SJL/J m 0.4544 0.0461 0.5451 0.3638
SM/J f 0.543 0.0438 0.629 0.457
SM/J m 0.5438 0.0489 0.6399 0.4476
SWR/J f 0.3067 0.0461 0.3973 0.216
SWR/J m 0.396 0.0438 0.482 0.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.3079 0.0336 0.374 0.2419
A/J both 0.6897 0.0318 0.7522 0.6273
AKR/J both 0.731 0.0336 0.7971 0.665
BALB/cByJ both 0.5756 0.0346 0.6436 0.5077
BALB/cJ both 0.6176 0.0328 0.6821 0.5531
BTBR T+ Itpr3tf/J both 0.5215 0.0309 0.5823 0.4607
BUB/BnJ both 0.6581 0.0318 0.7205 0.5956
C3H/HeJ both 0.6423 0.0318 0.7048 0.5799
C57BL/10J both 0.3479 0.0318 0.4104 0.2855
C57BL/6J both 0.4875 0.0346 0.5555 0.4195
C57BLKS/J both 0.3517 0.0305 0.4116 0.2917
C57BR/cdJ both 0.4942 0.0341 0.5612 0.4272
C57L/J both 0.4583 0.0357 0.5285 0.3881
CBA/J both 0.5916 0.0328 0.6561 0.5271
CE/J both 0.5694 0.0326 0.6335 0.5054
DBA/1J both 0.5248 0.0318 0.5872 0.4623
DBA/2J both 0.484 0.0309 0.5448 0.4232
FVB/NJ both 0.499 0.0309 0.5598 0.4382
I/LnJ both 0.6015 0.0336 0.6675 0.5354
KK/HlJ both 0.5163 0.0318 0.5788 0.4539
LP/J both 0.3423 0.0318 0.4048 0.2799
NOD/ShiLtJ both 0.5211 0.0326 0.5852 0.457
NON/ShiLtJ both 0.6386 0.037 0.7112 0.5659
NZW/LacJ both 0.3568 0.0328 0.4212 0.2923
PL/J both 0.6199 0.0336 0.686 0.5539
RIIIS/J both 0.6447 0.0365 0.7164 0.5731
SJL/J both 0.4316 0.0336 0.4977 0.3655
SM/J both 0.5434 0.0328 0.6079 0.4789
SWR/J both 0.3513 0.0318 0.4138 0.2889




  GWAS USING LINEAR MIXED MODELS