Project measure / variable:   Berndt2   exp_flow_mch20

ID, description, units MPD:35151   exp_flow_mch20   expiratory flow rate   [mL/kg/s]  20 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - expiratory flow rate 20 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means1.68   mL/kg/s 1.92   mL/kg/s
Median of the strain means1.89   mL/kg/s 1.99   mL/kg/s
SD of the strain means± 0.608 ± 0.654
Coefficient of variation (CV)0.361 0.341
Min–max range of strain means0.593   –   2.94   mL/kg/s 0.831   –   2.94   mL/kg/s
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 7.084 7.084 27.5511 < 0.0001
strain 28 163.7504 5.8482 22.7449 < 0.0001
sex:strain 28 16.2632 0.5808 2.259 0.0003
Residuals 412 105.9346 0.2571


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.99 0.73   8 0.258 0.367 1.16, 3.43 0.51
129S1/SvImJ m 2.08 0.711   8 0.252 0.342 0.808, 2.84 0.25
A/J f 1.08 0.332   8 0.117 0.308 0.681, 1.73 -0.99
A/J m 1.01 0.196   8 0.0692 0.193 0.782, 1.39 -1.39
AKR/J f 2.02 1.01   8 0.356 0.499 1.13, 4.34 0.56
AKR/J m 2.61 0.639   8 0.226 0.245 1.6, 3.33 1.06
BALB/cByJ f 1.95 0.631   8 0.223 0.323 1.36, 3.36 0.44
BALB/cByJ m 2.33 0.716   8 0.253 0.307 1.18, 3.42 0.63
BALB/cJ f 2.16 0.402   10 0.127 0.186 1.49, 2.94 0.79
BALB/cJ m 2.49 0.518   10 0.164 0.208 1.34, 3.07 0.87
BTBR T+ Itpr3tf/J f 2.15 0.466   8 0.165 0.217 1.77, 3.19 0.77
BTBR T+ Itpr3tf/J m 2.63 0.552   8 0.195 0.21 1.53, 3.22 1.09
BUB/BnJ f 1.89 0.643   7 0.243 0.34 0.73, 2.79 0.34
BUB/BnJ m 1.53 0.575   8 0.203 0.375 0.819, 2.73 -0.59
C3H/HeJ f 1.16 0.407   8 0.144 0.35 0.686, 1.82 -0.86
C3H/HeJ m 1.35 0.704   8 0.249 0.522 0.398, 2.54 -0.87
C57BL/10J f 2.33 0.501   8 0.177 0.215 1.53, 3.07 1.07
C57BL/10J m 2.5 0.472   7 0.178 0.189 1.96, 3.29 0.89
C57BL/6J f 2.21 0.647   7 0.244 0.292 1.47, 3.04 0.87
C57BL/6J m 2.77 0.754   13 0.209 0.273 1.12, 3.9 1.3
C57BLKS/J f 2.31 0.78   11 0.235 0.338 0.942, 3.38 1.03
C57BLKS/J m 2.62 0.651   8 0.23 0.249 1.94, 3.94 1.07
C57BR/cdJ f 2.94 0.81   6 0.33 0.276 1.85, 4.15 2.07
C57BR/cdJ m 2.64 0.663   8 0.235 0.251 1.49, 3.54 1.1
C57L/J f 2.22 0.397   8 0.14 0.178 1.58, 2.59 0.89
C57L/J m 2.71 0.29   8 0.103 0.107 2.37, 3.2 1.21
CBA/J f 2.44 0.39   8 0.138 0.16 1.91, 3.02 1.25
CBA/J m 2.64 0.33   8 0.117 0.125 2.13, 2.91 1.1
CE/J f 1.39 0.443   8 0.157 0.319 0.964, 2.15 -0.48
CE/J m 1.35 0.325   9 0.108 0.24 0.865, 1.82 -0.87
DBA/1J f 1.59 0.426   10 0.135 0.268 1.11, 2.67 -0.15
DBA/1J m 1.34 0.293   8 0.104 0.219 0.901, 1.74 -0.89
DBA/2J f 1.57 0.37   8 0.131 0.235 1.11, 2.28 -0.18
DBA/2J m 1.72 0.373   10 0.118 0.217 1.25, 2.66 -0.3
FVB/NJ f 1.33 0.508   8 0.179 0.383 0.703, 1.93 -0.58
FVB/NJ m 2.94 0.483   7 0.182 0.164 2.18, 3.61 1.56
I/LnJ f 1.33 0.555   7 0.21 0.418 0.488, 2.12 -0.58
I/LnJ m 2.04 0.939   5 0.42 0.46 0.922, 2.9 0.19
KK/HlJ f 2.08 0.497   8 0.176 0.239 1.15, 2.82 0.66
KK/HlJ m 1.99 0.427   6 0.174 0.215 1.39, 2.51 0.11
LP/J f 0.656 0.344   8 0.122 0.525 0.18, 1.19 -1.69
LP/J m 1.26 0.576   8 0.204 0.457 0.786, 2.53 -1.01
NOD/ShiLtJ f 2.15 0.522   8 0.185 0.243 1.47, 3.13 0.77
NOD/ShiLtJ m 2.14 0.441   8 0.156 0.206 1.63, 2.74 0.34
NON/ShiLtJ f 0.865 0.204   8 0.0722 0.236 0.578, 1.19 -1.34
NON/ShiLtJ m 1.11 0.273   8 0.0966 0.246 0.824, 1.6 -1.24
NZW/LacJ f 1.29 0.26   8 0.092 0.202 0.798, 1.62 -0.64
NZW/LacJ m 1.45 0.509   8 0.18 0.351 0.769, 2.19 -0.72
PL/J f 0.593 0.215   8 0.076 0.362 0.328, 0.991 -1.79
PL/J m 0.831 0.397   8 0.14 0.478 0.55, 1.71 -1.66
RIIIS/J f 1.56 0.305   8 0.108 0.196 1.29, 2.24 -0.2
RIIIS/J m 1.31 0.296   8 0.105 0.226 0.944, 1.88 -0.93
SJL/J f 0.809 0.316   8 0.112 0.391 0.482, 1.43 -1.44
SJL/J m 0.939 0.241   8 0.0851 0.257 0.726, 1.39 -1.5
SM/J f 1.91 0.184   8 0.0649 0.0959 1.68, 2.21 0.38
SM/J m 1.96 0.367   8 0.13 0.187 1.41, 2.48 0.06
SWR/J f 0.799 0.202   8 0.0713 0.253 0.537, 1.1 -1.45
SWR/J m 1.36 0.205   9 0.0683 0.15 1.06, 1.7 -0.85


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.9887 0.1793 2.3412 1.6363
129S1/SvImJ m 2.0773 0.1793 2.4297 1.7248
A/J f 1.0765 0.1793 1.4289 0.7241
A/J m 1.0145 0.1793 1.3669 0.6621
AKR/J f 2.0188 0.1793 2.3712 1.6663
AKR/J m 2.6088 0.1793 2.9612 2.2563
BALB/cByJ f 1.9513 0.1793 2.3037 1.5988
BALB/cByJ m 2.335 0.1793 2.6874 1.9826
BALB/cJ f 2.163 0.1604 2.4782 1.8478
BALB/cJ m 2.492 0.1604 2.8072 2.1768
BTBR T+ Itpr3tf/J f 2.1525 0.1793 2.5049 1.8001
BTBR T+ Itpr3tf/J m 2.6325 0.1793 2.9849 2.2801
BUB/BnJ f 1.89 0.1917 2.2667 1.5133
BUB/BnJ m 1.5324 0.1793 1.8848 1.18
C3H/HeJ f 1.1614 0.1793 1.5138 0.809
C3H/HeJ m 1.3473 0.1793 1.6997 0.9948
C57BL/10J f 2.3275 0.1793 2.6799 1.9751
C57BL/10J m 2.4957 0.1917 2.8725 2.119
C57BL/6J f 2.2129 0.1917 2.5896 1.8361
C57BL/6J m 2.7662 0.1406 3.0426 2.4897
C57BLKS/J f 2.3084 0.1529 2.6089 2.0078
C57BLKS/J m 2.6163 0.1793 2.9687 2.2638
C57BR/cdJ f 2.9383 0.207 3.3453 2.5314
C57BR/cdJ m 2.6413 0.1793 2.9937 2.2888
C57L/J f 2.225 0.1793 2.5774 1.8726
C57L/J m 2.705 0.1793 3.0574 2.3526
CBA/J f 2.4362 0.1793 2.7887 2.0838
CBA/J m 2.6388 0.1793 2.9912 2.2863
CE/J f 1.3905 0.1793 1.7429 1.0381
CE/J m 1.3529 0.169 1.6851 1.0206
DBA/1J f 1.586 0.1604 1.9012 1.2708
DBA/1J m 1.3375 0.1793 1.6899 0.9851
DBA/2J f 1.575 0.1793 1.9274 1.2226
DBA/2J m 1.719 0.1604 2.0342 1.4038
FVB/NJ f 1.3264 0.1793 1.6788 0.974
FVB/NJ m 2.94 0.1917 3.3167 2.5633
I/LnJ f 1.3276 0.1917 1.7043 0.9508
I/LnJ m 2.0424 0.2268 2.4882 1.5966
KK/HlJ f 2.0825 0.1793 2.4349 1.7301
KK/HlJ m 1.99 0.207 2.3969 1.5831
LP/J f 0.6556 0.1793 1.008 0.3032
LP/J m 1.2602 0.1793 1.6127 0.9078
NOD/ShiLtJ f 2.1475 0.1793 2.4999 1.7951
NOD/ShiLtJ m 2.1413 0.1793 2.4937 1.7888
NON/ShiLtJ f 0.8647 0.1793 1.2172 0.5123
NON/ShiLtJ m 1.109 0.1793 1.4614 0.7566
NZW/LacJ f 1.2897 0.1793 1.6422 0.9373
NZW/LacJ m 1.4471 0.1793 1.7995 1.0947
PL/J f 0.5929 0.1793 0.9453 0.2405
PL/J m 0.8306 0.1793 1.183 0.4782
RIIIS/J f 1.5587 0.1793 1.9112 1.2063
RIIIS/J m 1.3093 0.1793 1.6617 0.9568
SJL/J f 0.8089 0.1793 1.1613 0.4565
SJL/J m 0.9386 0.1793 1.291 0.5862
SM/J f 1.9137 0.1793 2.2662 1.5613
SM/J m 1.9613 0.1793 2.3137 1.6088
SWR/J f 0.7989 0.1793 1.1513 0.4465
SWR/J m 1.3622 0.169 1.6945 1.03


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.033 0.1268 2.2822 1.7838
A/J both 1.0455 0.1268 1.2947 0.7963
AKR/J both 2.3138 0.1268 2.5629 2.0646
BALB/cByJ both 2.1431 0.1268 2.3923 1.8939
BALB/cJ both 2.3275 0.1134 2.5504 2.1046
BTBR T+ Itpr3tf/J both 2.3925 0.1268 2.6417 2.1433
BUB/BnJ both 1.7112 0.1312 1.9691 1.4532
C3H/HeJ both 1.2543 0.1268 1.5035 1.0051
C57BL/10J both 2.4116 0.1312 2.6695 2.1537
C57BL/6J both 2.4895 0.1189 2.7232 2.2559
C57BLKS/J both 2.4623 0.1178 2.6939 2.2307
C57BR/cdJ both 2.7898 0.1369 3.059 2.5206
C57L/J both 2.465 0.1268 2.7142 2.2158
CBA/J both 2.5375 0.1268 2.7867 2.2883
CE/J both 1.3717 0.1232 1.6139 1.1295
DBA/1J both 1.4617 0.1203 1.6982 1.2253
DBA/2J both 1.647 0.1203 1.8834 1.4106
FVB/NJ both 2.1332 0.1312 2.3911 1.8752
I/LnJ both 1.685 0.1485 1.9768 1.3932
KK/HlJ both 2.0363 0.1369 2.3054 1.7671
LP/J both 0.9579 0.1268 1.2071 0.7087
NOD/ShiLtJ both 2.1444 0.1268 2.3936 1.8952
NON/ShiLtJ both 0.9869 0.1268 1.2361 0.7377
NZW/LacJ both 1.3684 0.1268 1.6176 1.1192
PL/J both 0.7118 0.1268 0.9609 0.4626
RIIIS/J both 1.434 0.1268 1.6832 1.1848
SJL/J both 0.8737 0.1268 1.1229 0.6246
SM/J both 1.9375 0.1268 2.1867 1.6883
SWR/J both 1.0805 0.1232 1.3227 0.8384




  GWAS USING LINEAR MIXED MODELS