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Project measure / variable:   Berndt2   insp_flow_mch5

ID, description, units MPD:35142   insp_flow_mch5   inspiratory flow rate   [mL/kg/s]  5 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - inspiratory flow rate 5 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means2.69   mL/kg/s 2.86   mL/kg/s
Median of the strain means2.65   mL/kg/s 2.80   mL/kg/s
SD of the strain means± 0.558 ± 0.745
Coefficient of variation (CV)0.207 0.261
Min–max range of strain means1.74   –   4.29   mL/kg/s 1.77   –   5.46   mL/kg/s
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.9233 2.9233 6.6028 0.0105
strain 28 179.8181 6.4221 14.5054 < 0.0001
sex:strain 28 24.2069 0.8645 1.9527 0.003
Residuals 412 182.407 0.4427


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.18 0.29   8 0.103 0.133 1.77, 2.66 -0.92
129S1/SvImJ m 2.24 0.745   8 0.264 0.333 1.55, 3.59 -0.83
A/J f 2.92 0.383   8 0.135 0.131 2.41, 3.5 0.41
A/J m 2.97 0.41   8 0.145 0.138 2.45, 3.58 0.15
AKR/J f 2.89 0.794   8 0.281 0.275 1.64, 4.02 0.35
AKR/J m 2.37 0.493   8 0.174 0.208 1.64, 3.11 -0.65
BALB/cByJ f 3.52 0.564   8 0.199 0.16 2.73, 4.49 1.48
BALB/cByJ m 3.86 0.594   8 0.21 0.154 2.79, 4.61 1.35
BALB/cJ f 4.29 0.695   10 0.22 0.162 3.42, 5.72 2.86
BALB/cJ m 4.31 0.83   10 0.263 0.193 3.3, 5.91 1.95
BTBR T+ Itpr3tf/J f 3.65 1.02   8 0.362 0.281 2.28, 5.69 1.71
BTBR T+ Itpr3tf/J m 5.46 0.584   8 0.206 0.107 4.93, 6.42 3.5
BUB/BnJ f 2.96 0.867   7 0.328 0.293 1.78, 4.32 0.48
BUB/BnJ m 2.55 0.741   8 0.262 0.291 1.75, 4.06 -0.41
C3H/HeJ f 2.37 0.532   8 0.188 0.225 1.52, 3.06 -0.58
C3H/HeJ m 2.77 0.903   8 0.319 0.326 1.64, 4.7 -0.11
C57BL/10J f 3.29 0.415   8 0.147 0.126 2.79, 3.95 1.07
C57BL/10J m 3.45 0.596   7 0.225 0.173 2.77, 4.5 0.8
C57BL/6J f 2.94 0.254   7 0.096 0.0863 2.67, 3.4 0.44
C57BL/6J m 2.87 0.794   13 0.22 0.276 1.58, 4.32 0.02
C57BLKS/J f 2.89 0.759   11 0.229 0.263 1.54, 3.96 0.35
C57BLKS/J m 2.9 0.771   8 0.273 0.266 1.56, 3.51 0.06
C57BR/cdJ f 3.34 1.25   6 0.511 0.375 2.53, 5.78 1.16
C57BR/cdJ m 3.12 1.1   8 0.388 0.351 1.96, 5.4 0.36
C57L/J f 2.74 0.25   8 0.0884 0.0913 2.43, 3.13 0.08
C57L/J m 3.36 0.437   8 0.154 0.13 2.73, 3.84 0.68
CBA/J f 2.52 0.136   8 0.0481 0.054 2.27, 2.69 -0.31
CBA/J m 2.64 0.451   8 0.16 0.171 1.91, 3.12 -0.29
CE/J f 2.37 0.501   8 0.177 0.212 1.28, 2.91 -0.58
CE/J m 2.56 0.472   9 0.157 0.184 1.51, 3.0 -0.4
DBA/1J f 2.05 0.551   10 0.174 0.269 1.33, 2.75 -1.15
DBA/1J m 2.85 0.499   8 0.176 0.175 2.3, 3.55 -0.01
DBA/2J f 2.45 0.485   8 0.171 0.198 1.59, 3.18 -0.44
DBA/2J m 2.22 0.424   10 0.134 0.191 1.56, 2.8 -0.85
FVB/NJ f 2.53 1.11   8 0.394 0.44 1.38, 4.22 -0.29
FVB/NJ m 3.3 1.59   7 0.601 0.482 1.87, 6.06 0.6
I/LnJ f 2.51 0.566   7 0.214 0.226 1.6, 3.2 -0.33
I/LnJ m 2.88 0.362   5 0.162 0.126 2.36, 3.22 0.03
KK/HlJ f 2.94 0.459   8 0.162 0.156 2.12, 3.58 0.44
KK/HlJ m 2.57 0.579   6 0.237 0.226 1.93, 3.5 -0.38
LP/J f 1.98 0.659   8 0.233 0.333 1.17, 3.0 -1.28
LP/J m 2.23 0.745   8 0.263 0.334 1.12, 3.32 -0.84
NOD/ShiLtJ f 2.55 0.661   8 0.234 0.259 1.65, 3.88 -0.26
NOD/ShiLtJ m 2.8 0.882   8 0.312 0.315 2.09, 4.65 -0.07
NON/ShiLtJ f 2.65 0.645   8 0.228 0.243 1.83, 3.92 -0.08
NON/ShiLtJ m 3.0 0.551   8 0.195 0.183 2.24, 3.89 0.19
NZW/LacJ f 2.72 0.611   8 0.216 0.225 1.8, 3.29 0.05
NZW/LacJ m 2.15 0.453   8 0.16 0.211 1.5, 2.94 -0.95
PL/J f 2.24 0.317   8 0.112 0.141 1.85, 2.77 -0.81
PL/J m 2.36 0.57   8 0.202 0.241 1.59, 3.13 -0.66
RIIIS/J f 2.17 0.301   8 0.107 0.139 1.72, 2.55 -0.94
RIIIS/J m 2.32 0.265   8 0.0936 0.114 1.96, 2.78 -0.72
SJL/J f 1.98 0.818   8 0.289 0.412 1.16, 3.04 -1.28
SJL/J m 1.77 0.656   8 0.232 0.37 1.07, 2.72 -1.46
SM/J f 2.74 0.564   8 0.199 0.206 1.96, 3.68 0.08
SM/J m 2.95 0.836   8 0.295 0.283 2.0, 4.77 0.13
SWR/J f 1.74 0.518   8 0.183 0.297 1.04, 2.48 -1.71
SWR/J m 1.97 0.47   9 0.157 0.238 1.49, 2.99 -1.19


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.1787 0.2352 2.6412 1.7163
129S1/SvImJ m 2.2363 0.2352 2.6987 1.7738
A/J f 2.9237 0.2352 3.3862 2.4613
A/J m 2.975 0.2352 3.4374 2.5126
AKR/J f 2.8925 0.2352 3.3549 2.4301
AKR/J m 2.3675 0.2352 2.8299 1.9051
BALB/cByJ f 3.5187 0.2352 3.9812 3.0563
BALB/cByJ m 3.8613 0.2352 4.3237 3.3988
BALB/cJ f 4.29 0.2104 4.7036 3.8764
BALB/cJ m 4.305 0.2104 4.7186 3.8914
BTBR T+ Itpr3tf/J f 3.645 0.2352 4.1074 3.1826
BTBR T+ Itpr3tf/J m 5.46 0.2352 5.9224 4.9976
BUB/BnJ f 2.9557 0.2515 3.4501 2.4613
BUB/BnJ m 2.5463 0.2352 3.0087 2.0838
C3H/HeJ f 2.3712 0.2352 2.8337 1.9088
C3H/HeJ m 2.77 0.2352 3.2324 2.3076
C57BL/10J f 3.2925 0.2352 3.7549 2.8301
C57BL/10J m 3.4486 0.2515 3.9429 2.9542
C57BL/6J f 2.9414 0.2515 3.4358 2.4471
C57BL/6J m 2.8746 0.1845 3.2374 2.5118
C57BLKS/J f 2.8927 0.2006 3.2871 2.4984
C57BLKS/J m 2.9013 0.2352 3.3637 2.4388
C57BR/cdJ f 3.3367 0.2716 3.8706 2.8027
C57BR/cdJ m 3.1188 0.2352 3.5812 2.6563
C57L/J f 2.7387 0.2352 3.2012 2.2763
C57L/J m 3.3613 0.2352 3.8237 2.8988
CBA/J f 2.5175 0.2352 2.9799 2.0551
CBA/J m 2.6413 0.2352 3.1037 2.1788
CE/J f 2.365 0.2352 2.8274 1.9026
CE/J m 2.56 0.2218 2.996 2.124
DBA/1J f 2.051 0.2104 2.4646 1.6374
DBA/1J m 2.85 0.2352 3.3124 2.3876
DBA/2J f 2.4525 0.2352 2.9149 1.9901
DBA/2J m 2.216 0.2104 2.6296 1.8024
FVB/NJ f 2.5325 0.2352 2.9949 2.0701
FVB/NJ m 3.2971 0.2515 3.7915 2.8028
I/LnJ f 2.5071 0.2515 3.0015 2.0128
I/LnJ m 2.88 0.2976 3.4649 2.2951
KK/HlJ f 2.935 0.2352 3.3974 2.4726
KK/HlJ m 2.5667 0.2716 3.1006 2.0327
LP/J f 1.9812 0.2352 2.4437 1.5188
LP/J m 2.23 0.2352 2.6924 1.7676
NOD/ShiLtJ f 2.5475 0.2352 3.0099 2.0851
NOD/ShiLtJ m 2.8 0.2352 3.2624 2.3376
NON/ShiLtJ f 2.65 0.2352 3.1124 2.1876
NON/ShiLtJ m 3.0038 0.2352 3.4662 2.5413
NZW/LacJ f 2.72 0.2352 3.1824 2.2576
NZW/LacJ m 2.1475 0.2352 2.6099 1.6851
PL/J f 2.2438 0.2352 2.7062 1.7813
PL/J m 2.3638 0.2352 2.8262 1.9013
RIIIS/J f 2.165 0.2352 2.6274 1.7026
RIIIS/J m 2.3238 0.2352 2.7862 1.8613
SJL/J f 1.9837 0.2352 2.4462 1.5213
SJL/J m 1.7738 0.2352 2.2362 1.3113
SM/J f 2.7437 0.2352 3.2062 2.2813
SM/J m 2.9513 0.2352 3.4137 2.4888
SWR/J f 1.745 0.2352 2.2074 1.2826
SWR/J m 1.9722 0.2218 2.4082 1.5362


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.2075 0.1663 2.5345 1.8805
A/J both 2.9494 0.1663 3.2764 2.6224
AKR/J both 2.63 0.1663 2.957 2.303
BALB/cByJ both 3.69 0.1663 4.017 3.363
BALB/cJ both 4.2975 0.1488 4.59 4.005
BTBR T+ Itpr3tf/J both 4.5525 0.1663 4.8795 4.2255
BUB/BnJ both 2.751 0.1722 3.0895 2.4125
C3H/HeJ both 2.5706 0.1663 2.8976 2.2436
C57BL/10J both 3.3705 0.1722 3.709 3.0321
C57BL/6J both 2.908 0.156 3.2146 2.6014
C57BLKS/J both 2.897 0.1546 3.2009 2.5931
C57BR/cdJ both 3.2277 0.1797 3.5809 2.8745
C57L/J both 3.05 0.1663 3.377 2.723
CBA/J both 2.5794 0.1663 2.9064 2.2524
CE/J both 2.4625 0.1617 2.7803 2.1447
DBA/1J both 2.4505 0.1578 2.7607 2.1403
DBA/2J both 2.3343 0.1578 2.6445 2.024
FVB/NJ both 2.9148 0.1722 3.2533 2.5764
I/LnJ both 2.6936 0.1948 3.0765 2.3106
KK/HlJ both 2.7508 0.1797 3.104 2.3976
LP/J both 2.1056 0.1663 2.4326 1.7786
NOD/ShiLtJ both 2.6738 0.1663 3.0007 2.3468
NON/ShiLtJ both 2.8269 0.1663 3.1539 2.4999
NZW/LacJ both 2.4337 0.1663 2.7607 2.1068
PL/J both 2.3038 0.1663 2.6307 1.9768
RIIIS/J both 2.2444 0.1663 2.5714 1.9174
SJL/J both 1.8788 0.1663 2.2057 1.5518
SM/J both 2.8475 0.1663 3.1745 2.5205
SWR/J both 1.8586 0.1617 2.1764 1.5408




  GWAS USING LINEAR MIXED MODELS