Project measure / variable:   Berndt2   duty_cycle_mch5

ID, description, units MPD:35135   duty_cycle_mch5   duty cycle   [ratio]  5 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - duty cycle 5 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.303   ratio 0.315   ratio
Median of the strain means0.307   ratio 0.314   ratio
SD of the strain means± 0.0300 ± 0.0304
Coefficient of variation (CV)0.0990 0.0965
Min–max range of strain means0.248   –   0.352   ratio 0.263   –   0.390   ratio
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0151 0.0151 14.112 0.0002
strain 28 0.3722 0.0133 12.443 < 0.0001
sex:strain 28 0.0434 0.0016 1.4519 0.0665
Residuals 412 0.4401 0.0011


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.26 0.0438   8 0.0155 0.168 0.22, 0.333 -1.44
129S1/SvImJ m 0.287 0.0373   8 0.0132 0.13 0.242, 0.345 -0.91
A/J f 0.323 0.0327   8 0.0116 0.101 0.275, 0.375 0.66
A/J m 0.314 0.0251   8 0.00888 0.0801 0.278, 0.348 -0.02
AKR/J f 0.336 0.0507   8 0.0179 0.151 0.282, 0.442 1.09
AKR/J m 0.324 0.039   8 0.0138 0.12 0.251, 0.375 0.31
BALB/cByJ f 0.297 0.0265   8 0.00936 0.0891 0.26, 0.333 -0.21
BALB/cByJ m 0.304 0.0319   8 0.0113 0.105 0.242, 0.344 -0.35
BALB/cJ f 0.314 0.0339   10 0.0107 0.108 0.262, 0.366 0.36
BALB/cJ m 0.333 0.016   10 0.00507 0.0483 0.307, 0.359 0.61
BTBR T+ Itpr3tf/J f 0.352 0.0294   8 0.0104 0.0834 0.312, 0.402 1.62
BTBR T+ Itpr3tf/J m 0.39 0.0215   8 0.00759 0.055 0.356, 0.418 2.48
BUB/BnJ f 0.312 0.0115   7 0.00435 0.0368 0.295, 0.326 0.29
BUB/BnJ m 0.292 0.0376   8 0.0133 0.129 0.222, 0.338 -0.74
C3H/HeJ f 0.279 0.0249   8 0.00882 0.0893 0.233, 0.315 -0.81
C3H/HeJ m 0.277 0.0271   8 0.00958 0.0977 0.22, 0.308 -1.24
C57BL/10J f 0.296 0.0307   8 0.0109 0.104 0.246, 0.326 -0.24
C57BL/10J m 0.308 0.0284   7 0.0107 0.0921 0.262, 0.337 -0.22
C57BL/6J f 0.264 0.0218   7 0.00822 0.0823 0.237, 0.301 -1.31
C57BL/6J m 0.285 0.029   13 0.00804 0.102 0.235, 0.328 -0.98
C57BLKS/J f 0.286 0.0308   11 0.00927 0.108 0.225, 0.331 -0.58
C57BLKS/J m 0.295 0.0277   8 0.00979 0.0939 0.254, 0.323 -0.65
C57BR/cdJ f 0.337 0.0565   6 0.0231 0.168 0.271, 0.437 1.12
C57BR/cdJ m 0.316 0.0422   8 0.0149 0.133 0.236, 0.356 0.05
C57L/J f 0.304 0.0266   8 0.0094 0.0875 0.265, 0.345 0.02
C57L/J m 0.29 0.0346   8 0.0122 0.119 0.228, 0.338 -0.81
CBA/J f 0.308 0.0104   8 0.00369 0.0338 0.298, 0.328 0.16
CBA/J m 0.319 0.0331   8 0.0117 0.104 0.282, 0.379 0.14
CE/J f 0.307 0.0266   8 0.0094 0.0865 0.277, 0.358 0.12
CE/J m 0.325 0.0571   9 0.019 0.176 0.261, 0.437 0.34
DBA/1J f 0.35 0.0484   10 0.0153 0.138 0.266, 0.405 1.56
DBA/1J m 0.325 0.0393   8 0.0139 0.121 0.248, 0.369 0.34
DBA/2J f 0.329 0.0119   8 0.00419 0.036 0.311, 0.344 0.86
DBA/2J m 0.359 0.0179   10 0.00567 0.05 0.335, 0.392 1.46
FVB/NJ f 0.309 0.0247   8 0.00874 0.08 0.28, 0.34 0.19
FVB/NJ m 0.352 0.0244   7 0.00922 0.0692 0.302, 0.377 1.23
I/LnJ f 0.295 0.0332   7 0.0126 0.113 0.232, 0.334 -0.28
I/LnJ m 0.308 0.0209   5 0.00934 0.0677 0.282, 0.332 -0.22
KK/HlJ f 0.281 0.0172   8 0.00609 0.0613 0.257, 0.304 -0.74
KK/HlJ m 0.289 0.0367   6 0.015 0.127 0.239, 0.328 -0.84
LP/J f 0.258 0.0402   8 0.0142 0.156 0.176, 0.301 -1.51
LP/J m 0.286 0.0277   8 0.00979 0.097 0.24, 0.329 -0.94
NOD/ShiLtJ f 0.248 0.0377   8 0.0133 0.152 0.202, 0.316 -1.84
NOD/ShiLtJ m 0.293 0.0594   8 0.021 0.202 0.226, 0.406 -0.71
NON/ShiLtJ f 0.258 0.0245   8 0.00868 0.0951 0.223, 0.293 -1.51
NON/ShiLtJ m 0.274 0.0352   8 0.0124 0.129 0.218, 0.323 -1.34
NZW/LacJ f 0.321 0.0149   8 0.00527 0.0465 0.3, 0.341 0.59
NZW/LacJ m 0.364 0.0164   8 0.00581 0.0452 0.344, 0.388 1.63
PL/J f 0.266 0.0283   8 0.00999 0.106 0.226, 0.3 -1.24
PL/J m 0.263 0.0404   8 0.0143 0.154 0.207, 0.338 -1.7
RIIIS/J f 0.329 0.0154   8 0.00543 0.0467 0.299, 0.352 0.86
RIIIS/J m 0.346 0.0295   8 0.0104 0.0852 0.315, 0.387 1.03
SJL/J f 0.301 0.0302   8 0.0107 0.101 0.265, 0.356 -0.08
SJL/J m 0.331 0.027   8 0.00955 0.0816 0.286, 0.361 0.54
SM/J f 0.35 0.0339   8 0.012 0.0969 0.284, 0.381 1.56
SM/J m 0.351 0.0512   8 0.0181 0.146 0.283, 0.423 1.2
SWR/J f 0.325 0.0288   8 0.0102 0.0888 0.289, 0.38 0.72
SWR/J m 0.324 0.0245   9 0.00815 0.0755 0.277, 0.359 0.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.2602 0.0116 0.283 0.2375
129S1/SvImJ m 0.2874 0.0116 0.3101 0.2647
A/J f 0.3231 0.0116 0.3458 0.3004
A/J m 0.3135 0.0116 0.3362 0.2908
AKR/J f 0.3358 0.0116 0.3585 0.313
AKR/J m 0.3244 0.0116 0.3471 0.3017
BALB/cByJ f 0.297 0.0116 0.3197 0.2743
BALB/cByJ m 0.3044 0.0116 0.3271 0.2817
BALB/cJ f 0.3138 0.0103 0.3341 0.2935
BALB/cJ m 0.3325 0.0103 0.3528 0.3122
BTBR T+ Itpr3tf/J f 0.3525 0.0116 0.3752 0.3298
BTBR T+ Itpr3tf/J m 0.3903 0.0116 0.413 0.3675
BUB/BnJ f 0.3124 0.0124 0.3367 0.2881
BUB/BnJ m 0.2923 0.0116 0.315 0.2695
C3H/HeJ f 0.2792 0.0116 0.302 0.2565
C3H/HeJ m 0.2774 0.0116 0.3001 0.2547
C57BL/10J f 0.2959 0.0116 0.3186 0.2732
C57BL/10J m 0.3084 0.0124 0.3327 0.2841
C57BL/6J f 0.2643 0.0124 0.2886 0.24
C57BL/6J m 0.2848 0.0091 0.3026 0.267
C57BLKS/J f 0.2856 0.0099 0.305 0.2663
C57BLKS/J m 0.2949 0.0116 0.3176 0.2722
C57BR/cdJ f 0.3368 0.0133 0.3631 0.3106
C57BR/cdJ m 0.3164 0.0116 0.3391 0.2937
C57L/J f 0.304 0.0116 0.3267 0.2813
C57L/J m 0.2902 0.0116 0.313 0.2675
CBA/J f 0.3085 0.0116 0.3312 0.2858
CBA/J m 0.3194 0.0116 0.3421 0.2967
CE/J f 0.3072 0.0116 0.33 0.2845
CE/J m 0.3247 0.0109 0.3461 0.3033
DBA/1J f 0.35 0.0103 0.3703 0.3297
DBA/1J m 0.3246 0.0116 0.3473 0.3019
DBA/2J f 0.3292 0.0116 0.352 0.3065
DBA/2J m 0.3586 0.0103 0.3789 0.3383
FVB/NJ f 0.3089 0.0116 0.3316 0.2862
FVB/NJ m 0.3521 0.0124 0.3764 0.3279
I/LnJ f 0.2953 0.0124 0.3196 0.271
I/LnJ m 0.3084 0.0146 0.3371 0.2797
KK/HlJ f 0.2814 0.0116 0.3041 0.2587
KK/HlJ m 0.2888 0.0133 0.3151 0.2626
LP/J f 0.258 0.0116 0.2807 0.2353
LP/J m 0.2856 0.0116 0.3083 0.2629
NOD/ShiLtJ f 0.248 0.0116 0.2707 0.2253
NOD/ShiLtJ m 0.2935 0.0116 0.3162 0.2708
NON/ShiLtJ f 0.2581 0.0116 0.2808 0.2354
NON/ShiLtJ m 0.2735 0.0116 0.2962 0.2508
NZW/LacJ f 0.3207 0.0116 0.3435 0.298
NZW/LacJ m 0.3636 0.0116 0.3863 0.3409
PL/J f 0.2661 0.0116 0.2888 0.2434
PL/J m 0.2625 0.0116 0.2852 0.2398
RIIIS/J f 0.3289 0.0116 0.3516 0.3062
RIIIS/J m 0.3465 0.0116 0.3692 0.3238
SJL/J f 0.3009 0.0116 0.3236 0.2782
SJL/J m 0.331 0.0116 0.3537 0.3083
SM/J f 0.3496 0.0116 0.3723 0.3269
SM/J m 0.3511 0.0116 0.3738 0.3284
SWR/J f 0.3245 0.0116 0.3472 0.3018
SWR/J m 0.3239 0.0109 0.3453 0.3025


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.2738 0.0082 0.2899 0.2578
A/J both 0.3183 0.0082 0.3344 0.3023
AKR/J both 0.3301 0.0082 0.3461 0.314
BALB/cByJ both 0.3007 0.0082 0.3167 0.2846
BALB/cJ both 0.3231 0.0073 0.3375 0.3088
BTBR T+ Itpr3tf/J both 0.3714 0.0082 0.3874 0.3553
BUB/BnJ both 0.3023 0.0085 0.319 0.2857
C3H/HeJ both 0.2783 0.0082 0.2944 0.2623
C57BL/10J both 0.3022 0.0085 0.3188 0.2855
C57BL/6J both 0.2745 0.0077 0.2896 0.2595
C57BLKS/J both 0.2903 0.0076 0.3052 0.2753
C57BR/cdJ both 0.3266 0.0088 0.344 0.3093
C57L/J both 0.2971 0.0082 0.3132 0.2811
CBA/J both 0.3139 0.0082 0.33 0.2979
CE/J both 0.316 0.0079 0.3316 0.3003
DBA/1J both 0.3373 0.0078 0.3525 0.3221
DBA/2J both 0.3439 0.0078 0.3592 0.3287
FVB/NJ both 0.3305 0.0085 0.3471 0.3139
I/LnJ both 0.3018 0.0096 0.3207 0.283
KK/HlJ both 0.2851 0.0088 0.3025 0.2678
LP/J both 0.2718 0.0082 0.2879 0.2558
NOD/ShiLtJ both 0.2708 0.0082 0.2868 0.2547
NON/ShiLtJ both 0.2658 0.0082 0.2819 0.2498
NZW/LacJ both 0.3422 0.0082 0.3582 0.3261
PL/J both 0.2643 0.0082 0.2804 0.2483
RIIIS/J both 0.3377 0.0082 0.3537 0.3216
SJL/J both 0.3159 0.0082 0.332 0.2999
SM/J both 0.3504 0.0082 0.3664 0.3343
SWR/J both 0.3242 0.0079 0.3398 0.3086




  GWAS USING LINEAR MIXED MODELS