Project measure / variable:   Berndt2   breath_freq_slope

ID, description, units MPD:35112   breath_freq_slope   breath frequency   [n/min]  response index  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - breath frequency response index



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means-0.0275   n/min -0.0349   n/min
Median of the strain means0.0201   n/min 0.00575   n/min
SD of the strain means± 0.143 ± 0.165
Coefficient of variation (CV)-5.21 -4.73
Min–max range of strain means-0.399   –   0.255   n/min -0.484   –   0.191   n/min
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0026 0.0026 0.0733 0.7867
strain 28 9.2512 0.3304 9.2855 < 0.0001
sex:strain 28 1.5049 0.0537 1.5104 0.0482
Residuals 412 14.66 0.0356


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.106 0.251   8 0.0889 2.37 -0.267, 0.399 0.93
129S1/SvImJ m 0.119 0.252   8 0.0891 2.12 -0.246, 0.473 0.93
A/J f -0.399 0.209   8 0.0738 -0.523 -0.602, -0.128 -2.59
A/J m -0.484 0.123   8 0.0434 -0.253 -0.676, -0.345 -2.72
AKR/J f -0.0448 0.0983   8 0.0348 -2.2 -0.22, 0.135 -0.12
AKR/J m 0.191 0.145   8 0.0514 0.763 -0.035, 0.373 1.37
BALB/cByJ f 0.0192 0.148   8 0.0525 7.71 -0.254, 0.253 0.33
BALB/cByJ m 0.0881 0.087   8 0.0308 0.987 -0.076, 0.207 0.74
BALB/cJ f 0.0407 0.0909   10 0.0287 2.23 -0.079, 0.174 0.48
BALB/cJ m 0.025 0.0737   10 0.0233 2.95 -0.134, 0.108 0.36
BTBR T+ Itpr3tf/J f -0.38 0.307   8 0.109 -0.808 -0.574, 0.357 -2.46
BTBR T+ Itpr3tf/J m -0.393 0.164   8 0.0579 -0.417 -0.729, -0.191 -2.17
BUB/BnJ f -0.0701 0.286   7 0.108 -4.08 -0.388, 0.468 -0.3
BUB/BnJ m -0.0875 0.27   8 0.0956 -3.09 -0.414, 0.271 -0.32
C3H/HeJ f 0.0257 0.293   8 0.103 11.4 -0.335, 0.375 0.37
C3H/HeJ m -0.0462 0.229   8 0.0809 -4.94 -0.309, 0.302 -0.07
C57BL/10J f 0.0636 0.109   8 0.0384 1.71 -0.154, 0.216 0.64
C57BL/10J m -0.0927 0.117   7 0.0441 -1.26 -0.287, 0.044 -0.35
C57BL/6J f 0.0833 0.0991   7 0.0374 1.19 -0.028, 0.209 0.77
C57BL/6J m 0.123 0.115   13 0.032 0.94 0.008, 0.349 0.96
C57BLKS/J f 0.0819 0.136   11 0.0412 1.67 -0.102, 0.287 0.76
C57BLKS/J m 0.00637 0.231   8 0.0815 36.2 -0.336, 0.392 0.25
C57BR/cdJ f 0.0777 0.137   6 0.056 1.76 -0.086, 0.22 0.73
C57BR/cdJ m 0.00963 0.161   8 0.057 16.7 -0.241, 0.198 0.27
C57L/J f 0.0653 0.0884   8 0.0313 1.36 -0.108, 0.151 0.65
C57L/J m 0.0296 0.0867   8 0.0306 2.93 -0.095, 0.175 0.39
CBA/J f 0.0398 0.0939   8 0.0332 2.36 -0.095, 0.159 0.47
CBA/J m 0.108 0.122   8 0.0432 1.13 -0.078, 0.251 0.86
CE/J f 0.0361 0.247   8 0.0875 6.85 -0.16, 0.574 0.44
CE/J m -0.0433 0.204   9 0.0681 -4.72 -0.304, 0.356 -0.05
DBA/1J f 0.0201 0.158   10 0.0501 7.88 -0.313, 0.222 0.33
DBA/1J m -0.346 0.151   8 0.0534 -0.437 -0.553, -0.118 -1.88
DBA/2J f -0.0808 0.147   8 0.052 -1.82 -0.308, 0.106 -0.37
DBA/2J m -0.0073 0.221   10 0.0699 -30.3 -0.241, 0.412 0.17
FVB/NJ f 0.0323 0.216   8 0.0765 6.71 -0.31, 0.323 0.42
FVB/NJ m 0.0954 0.167   7 0.0631 1.75 -0.115, 0.378 0.79
I/LnJ f -0.114 0.22   7 0.0833 -1.94 -0.423, 0.112 -0.6
I/LnJ m -0.162 0.344   5 0.154 -2.13 -0.693, 0.174 -0.77
KK/HlJ f 0.0987 0.152   8 0.0537 1.54 -0.191, 0.269 0.88
KK/HlJ m 0.079 0.203   6 0.0829 2.57 -0.138, 0.41 0.69
LP/J f 0.023 0.215   8 0.0761 9.36 -0.335, 0.318 0.35
LP/J m 0.147 0.157   8 0.0553 1.07 -0.072, 0.407 1.1
NOD/ShiLtJ f 0.255 0.187   8 0.0662 0.735 -0.162, 0.396 1.97
NOD/ShiLtJ m 0.162 0.278   8 0.0983 1.72 -0.326, 0.439 1.19
NON/ShiLtJ f -0.222 0.221   8 0.078 -0.993 -0.556, 0.061 -1.36
NON/ShiLtJ m -0.21 0.124   8 0.0438 -0.591 -0.358, 0.018 -1.06
NZW/LacJ f -0.112 0.114   8 0.0403 -1.02 -0.29, 0.058 -0.59
NZW/LacJ m 0.0702 0.14   8 0.0495 1.99 -0.132, 0.282 0.64
PL/J f -0.268 0.191   8 0.0676 -0.713 -0.519, -0.018 -1.68
PL/J m -0.0979 0.293   8 0.104 -3.0 -0.46, 0.465 -0.38
RIIIS/J f -0.0115 0.13   8 0.0459 -11.3 -0.117, 0.246 0.11
RIIIS/J m -0.08 0.13   8 0.0461 -1.63 -0.176, 0.162 -0.27
SJL/J f -0.0166 0.289   8 0.102 -17.4 -0.372, 0.371 0.08
SJL/J m 0.00575 0.193   8 0.0683 33.6 -0.336, 0.162 0.25
SM/J f -0.0966 0.129   8 0.0458 -1.34 -0.28, 0.094 -0.48
SM/J m -0.164 0.236   8 0.0833 -1.44 -0.516, 0.176 -0.78
SWR/J f -0.0504 0.302   8 0.107 -6.0 -0.437, 0.314 -0.16
SWR/J m -0.0579 0.111   9 0.0371 -1.92 -0.265, 0.063 -0.14


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.106 0.0667 0.2371 -0.0251
129S1/SvImJ m 0.119 0.0667 0.2501 -0.0121
A/J f -0.3985 0.0667 -0.2674 -0.5296
A/J m -0.4845 0.0667 -0.3534 -0.6156
AKR/J f -0.0448 0.0667 0.0863 -0.1758
AKR/J m 0.1906 0.0667 0.3217 0.0595
BALB/cByJ f 0.0193 0.0667 0.1503 -0.1118
BALB/cByJ m 0.0881 0.0667 0.2192 -0.043
BALB/cJ f 0.0407 0.0597 0.158 -0.0766
BALB/cJ m 0.025 0.0597 0.1423 -0.0923
BTBR T+ Itpr3tf/J f -0.3799 0.0667 -0.2488 -0.511
BTBR T+ Itpr3tf/J m -0.3926 0.0667 -0.2615 -0.5237
BUB/BnJ f -0.0701 0.0713 0.07 -0.2103
BUB/BnJ m -0.0875 0.0667 0.0436 -0.2186
C3H/HeJ f 0.0257 0.0667 0.1568 -0.1053
C3H/HeJ m -0.0462 0.0667 0.0848 -0.1773
C57BL/10J f 0.0636 0.0667 0.1947 -0.0675
C57BL/10J m -0.0927 0.0713 0.0474 -0.2329
C57BL/6J f 0.0833 0.0713 0.2234 -0.0569
C57BL/6J m 0.1225 0.0523 0.2254 0.0197
C57BLKS/J f 0.0819 0.0569 0.1937 -0.0299
C57BLKS/J m 0.0064 0.0667 0.1375 -0.1247
C57BR/cdJ f 0.0777 0.077 0.229 -0.0737
C57BR/cdJ m 0.0096 0.0667 0.1407 -0.1215
C57L/J f 0.0653 0.0667 0.1963 -0.0658
C57L/J m 0.0296 0.0667 0.1607 -0.1015
CBA/J f 0.0398 0.0667 0.1708 -0.0913
CBA/J m 0.1085 0.0667 0.2396 -0.0226
CE/J f 0.0361 0.0667 0.1672 -0.095
CE/J m -0.0433 0.0629 0.0803 -0.1669
DBA/1J f 0.0201 0.0597 0.1374 -0.0972
DBA/1J m -0.3456 0.0667 -0.2145 -0.4767
DBA/2J f -0.0808 0.0667 0.0503 -0.2118
DBA/2J m -0.0073 0.0597 0.11 -0.1246
FVB/NJ f 0.0322 0.0667 0.1633 -0.0988
FVB/NJ m 0.0954 0.0713 0.2356 -0.0447
I/LnJ f -0.1139 0.0713 0.0263 -0.254
I/LnJ m -0.1618 0.0844 0.004 -0.3276
KK/HlJ f 0.0988 0.0667 0.2298 -0.0323
KK/HlJ m 0.079 0.077 0.2304 -0.0724
LP/J f 0.023 0.0667 0.1541 -0.1081
LP/J m 0.1467 0.0667 0.2778 0.0157
NOD/ShiLtJ f 0.2548 0.0667 0.3858 0.1237
NOD/ShiLtJ m 0.1618 0.0667 0.2928 0.0307
NON/ShiLtJ f -0.2223 0.0667 -0.0912 -0.3533
NON/ShiLtJ m -0.2096 0.0667 -0.0785 -0.3407
NZW/LacJ f -0.1124 0.0667 0.0187 -0.2435
NZW/LacJ m 0.0703 0.0667 0.2013 -0.0608
PL/J f -0.268 0.0667 -0.1369 -0.3991
PL/J m -0.0979 0.0667 0.0332 -0.229
RIIIS/J f -0.0115 0.0667 0.1196 -0.1426
RIIIS/J m -0.08 0.0667 0.0511 -0.2111
SJL/J f -0.0166 0.0667 0.1145 -0.1477
SJL/J m 0.0058 0.0667 0.1368 -0.1253
SM/J f -0.0966 0.0667 0.0345 -0.2277
SM/J m -0.1641 0.0667 -0.033 -0.2952
SWR/J f -0.0504 0.0667 0.0807 -0.1815
SWR/J m -0.0579 0.0629 0.0657 -0.1815


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.1125 0.0472 0.2052 0.0198
A/J both -0.4415 0.0472 -0.3488 -0.5342
AKR/J both 0.0729 0.0472 0.1656 -0.0198
BALB/cByJ both 0.0537 0.0472 0.1464 -0.039
BALB/cJ both 0.0328 0.0422 0.1158 -0.0501
BTBR T+ Itpr3tf/J both -0.3862 0.0472 -0.2935 -0.479
BUB/BnJ both -0.0788 0.0488 0.0171 -0.1748
C3H/HeJ both -0.0102 0.0472 0.0825 -0.103
C57BL/10J both -0.0145 0.0488 0.0814 -0.1105
C57BL/6J both 0.1029 0.0442 0.1898 0.016
C57BLKS/J both 0.0441 0.0438 0.1303 -0.042
C57BR/cdJ both 0.0436 0.0509 0.1438 -0.0565
C57L/J both 0.0474 0.0472 0.1401 -0.0453
CBA/J both 0.0741 0.0472 0.1668 -0.0186
CE/J both -0.0036 0.0458 0.0865 -0.0937
DBA/1J both -0.1628 0.0447 -0.0748 -0.2507
DBA/2J both -0.044 0.0447 0.0439 -0.132
FVB/NJ both 0.0638 0.0488 0.1598 -0.0321
I/LnJ both -0.1378 0.0552 -0.0293 -0.2464
KK/HlJ both 0.0889 0.0509 0.189 -0.0113
LP/J both 0.0849 0.0472 0.1776 -0.0078
NOD/ShiLtJ both 0.2083 0.0472 0.301 0.1155
NON/ShiLtJ both -0.2159 0.0472 -0.1232 -0.3086
NZW/LacJ both -0.0211 0.0472 0.0716 -0.1138
PL/J both -0.1829 0.0472 -0.0902 -0.2756
RIIIS/J both -0.0458 0.0472 0.047 -0.1385
SJL/J both -0.0054 0.0472 0.0873 -0.0981
SM/J both -0.1304 0.0472 -0.0377 -0.2231
SWR/J both -0.0541 0.0458 0.036 -0.1442




  GWAS USING LINEAR MIXED MODELS