Project measure / variable:   Schonfeld1   TG

ID, description, units MPD:32343   TG   triglycerides (plasma TG, 5h fast)   [mg/dL]  
Data set, strains Schonfeld1   inbred   11 strains     sex: both     age: 9-13wks
Procedure lipid profile
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  STRAIN COMPARISON PLOT
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Schonfeld1 - triglycerides (plasma TG, 5h fast)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means143   mg/dL 107   mg/dL
Median of the strain means162   mg/dL 105   mg/dL
SD of the strain means± 48.7 ± 42.1
Coefficient of variation (CV)0.341 0.395
Min–max range of strain means61.1   –   204   mg/dL 44.7   –   174   mg/dL
Mean sample size per strain6.2   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 12969.0458 12969.0458 15.2793 0.0002
strain 8 123797.8675 15474.7334 18.2313 < 0.0001
sex:strain 8 70207.0983 8775.8873 10.3392 < 0.0001
Residuals 87 73845.428 848.798


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ f 152.0 59.8   10 18.9 0.393 86.8, 246.0 0.19
129X1/SvJ m 154.0 16.3   5 7.3 0.106 134.0, 178.0 1.12
AKR/J f 178.0 19.0   5 8.49 0.106 159.0, 203.0 0.73
BALB/cByJ f 171.0 34.0   10 10.7 0.199 116.0, 229.0 0.58
BALB/cByJ m 174.0 12.3   5 5.5 0.0707 154.0, 184.0 1.6
BALB/cJ m 44.7 12.7   5 5.68 0.284 32.9, 58.7 -1.47
C3H/HeJ f 178.0 48.1   5 21.5 0.271 92.6, 210.0 0.73
C3H/HeJ m 139.0 32.7   5 14.6 0.235 98.4, 179.0 0.77
C57BL/6ByJ f 125.0 19.9   5 8.89 0.159 95.6, 146.0 -0.36
C57BL/6ByJ m 59.2 16.6   5 7.4 0.28 45.6, 87.2 -1.13
C57BL/6J f 61.1 17.5   10 5.54 0.287 38.8, 98.0 -1.67
C57BL/6J m 89.2 4.17   5 1.86 0.0467 82.4, 92.8 -0.41
DBA/1LacJ f 114.0 19.5   5 8.71 0.171 88.0, 141.0 -0.59
DBA/1LacJ m 125.0 29.7   5 13.3 0.237 98.0, 172.0 0.44
NZB/BlNJ f 69.0 16.3   5 7.31 0.237 58.8, 97.2 -1.51
NZB/BlNJ m 114.0 8.46   5 3.78 0.0742 106.0, 125.0 0.17
PL/J f 204.0 22.5   5 10.1 0.11 177.0, 230.0 1.26
PL/J m 71.6 11.5   5 5.13 0.16 59.2, 88.4 -0.83
SWR/J f 174.0 14.4   5 6.43 0.0825 157.0, 185.0 0.64
SWR/J m 95.9 13.6   5 6.08 0.142 81.6, 111.0 -0.26


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ f 152.24 9.213 170.5519 133.9281
129X1/SvJ m 154.2 13.0292 180.0969 128.3031
BALB/cByJ f 171.1 9.213 189.4119 152.7881
BALB/cByJ m 173.8 13.0292 199.6969 147.9031
C3H/HeJ f 177.52 13.0292 203.4169 151.6231
C3H/HeJ m 139.08 13.0292 164.9769 113.1831
C57BL/6ByJ f 125.12 13.0292 151.0169 99.2231
C57BL/6ByJ m 59.2 13.0292 85.0969 33.3031
C57BL/6J f 61.12 9.213 79.4319 42.8081
C57BL/6J m 89.2 13.0292 115.0969 63.3031
DBA/1LacJ f 114.0 13.0292 139.8969 88.1031
DBA/1LacJ m 125.4 13.0292 151.2969 99.5031
NZB/BlNJ f 68.96 13.0292 94.8569 43.0631
NZB/BlNJ m 114.0 13.0292 139.8969 88.1031
PL/J f 204.0 13.0292 229.8969 178.1031
PL/J m 71.6 13.0292 97.4969 45.7031
SWR/J f 174.2 13.0292 200.0969 148.3031
SWR/J m 95.94 13.0292 121.8369 70.0431


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ both 153.22 7.9787 169.0786 137.3614
BALB/cByJ both 172.45 7.9787 188.3086 156.5914
C3H/HeJ both 158.3 9.213 176.6119 139.9881
C57BL/6ByJ both 92.16 9.213 110.4719 73.8481
C57BL/6J both 75.16 7.9787 91.0186 59.3014
DBA/1LacJ both 119.7 9.213 138.0119 101.3881
NZB/BlNJ both 91.48 9.213 109.7919 73.1681
PL/J both 137.8 9.213 156.1119 119.4881
SWR/J both 135.07 9.213 153.3819 116.7581




  GWAS USING LINEAR MIXED MODELS