Project measure / variable:   Paigen1   nstones

ID, description, units MPD:2918   nstones   gallbladder, number of sandy plus true stones   [n]  
high-fat diet study
Data set, strains Paigen1   inbred   43 strains     sex: both     age: 15-19wks
Procedure histopathology
Ontology mappings

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  STRAIN COMPARISON PLOT
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Paigen1 - gallbladder, number of sandy plus true stones



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested43 strains42 strains
Mean of the strain means0.853   n 3.18   n
Median of the strain means0.100   n 0.478   n
SD of the strain means± 1.96 ± 6.85
Coefficient of variation (CV)2.29 2.15
Min–max range of strain means0   –   10.2   n 0   –   38.0   n
Mean sample size per strain8.8   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 872.1685 872.1685 13.4505 0.0003
strain 41 11208.1902 273.3705 4.2159 < 0.0001
sex:strain 41 7501.0517 182.9525 2.8215 < 0.0001
Residuals 624 40461.906 64.8428


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.2 0.422   10 0.133 2.11 -0.33
129S1/SvImJ m 0.0 0.0   10 0.0 0.0 -0.46
A/J f 1.6 5.06   10 1.6 3.16 0.38
A/J m 1.0 3.16   10 1.0 3.16 -0.32
AKR/J f 0.0 0.0   9 0.0 0.0 -0.44
AKR/J m 0.0 0.0   9 0.0 0.0 -0.46
BALB/cJ f 0.1 0.316   10 0.1 3.16 -0.38
BALB/cJ m 1.1 1.66   10 0.526 1.51 -0.3
BPH/2J f 0.7 2.21   10 0.7 3.16 -0.08
BPH/2J m 0.0 0.0   9 0.0 0.0 -0.46
BPL/1J f 2.5 7.91   10 2.5 3.16 0.84
BPL/1J m 0.0 0.0   10 0.0 0.0 -0.46
BPN/3J f 0.0 0.0   10 0.0 0.0 -0.44
BPN/3J m 0.667 2.0   9 0.667 3.0 -0.37
BTBR T+ Itpr3tf/J f 0.0 0.0   3 0.0 0.0 -0.44
BTBR T+ Itpr3tf/J m 0.0 0.0   10 0.0 0.0 -0.46
C3H/HeJ f 0.0 0.0   9 0.0 0.0 -0.44
C3H/HeJ m 11.4 17.6   5 7.87 1.54 1.2
C57BL/10J f 2.5 6.28   10 1.98 2.51 0.84
C57BL/10J m 38.0 49.3   10 15.6 1.3 5.08
C57BL/6J f 0.2 0.632   10 0.2 3.16 -0.33
C57BL/6J m 4.67 4.08   6 1.67 0.875 0.22
C57BLKS/J f 0.167 0.408   6 0.167 2.45 -0.35
C57BLKS/J m 0.4 0.548   5 0.245 1.37 -0.41
C57BR/cdJ f 0.0 0.0   9 0.0 0.0 -0.44
C57BR/cdJ m 1.0 3.16   10 1.0 3.16 -0.32
C57L/J f 1.6 1.84   10 0.581 1.15 0.38
C57L/J m 4.8 3.97   10 1.25 0.826 0.24
C58/J f 7.0 7.29   10 2.3 1.04 3.14
C58/J m 8.0 9.14   10 2.89 1.14 0.7
CAST/EiJ f 0.0 0.0   5 0.0 0.0 -0.44
CAST/EiJ m 12.1 33.0   9 11.0 2.72 1.3
CBA/J f 0.0 0.0   9 0.0 0.0 -0.44
CBA/J m 0.7 1.49   10 0.473 2.13 -0.36
CE/J f 0.0 0.0   9 0.0 0.0 -0.44
CE/J m 0.0 0.0   6 0.0 0.0 -0.46
CZECHII/EiJ f 0.0 0.0   7 0.0 0.0 -0.44
CZECHII/EiJ m 0.571 1.51   7 0.571 2.65 -0.38
DBA/1J f 0.1 0.316   10 0.1 3.16 -0.38
DBA/1J m 0.0 0.0   8 0.0 0.0 -0.46
DBA/2J f 0.3 0.675   10 0.213 2.25 -0.28
DBA/2J m 0.0 0.0   9 0.0 0.0 -0.46
FVB/NJ f 0.0 0.0   9 0.0 0.0 -0.44
FVB/NJ m 7.0 7.21   3 4.16 1.03 1.0, 15.0 0.56
I/LnJ f 0.0 0.0   9 0.0 0.0 -0.44
I/LnJ m 0.0 0.0   9 0.0 0.0 -0.46
KK/HlJ f 0.0 0.0   8 0.0 0.0 -0.44
KK/HlJ m 0.0 0.0   9 0.0 0.0 -0.46
LP/J f 0.111 0.333   9 0.111 3.0 -0.38
LP/J m 0.111 0.333   9 0.111 3.0 -0.45
MOLF/EiJ f 1.0 1.66   9 0.553 1.66 0.08
MOLF/EiJ m 0.556 1.13   9 0.377 2.03 -0.38
NOD/ShiLtJ f 3.75 5.73   8 2.02 1.53 1.48
NOD/ShiLtJ m 10.5 24.3   6 9.91 2.31 1.07
NON/ShiLtJ f 0.0 0.0   9 0.0 0.0 -0.44
NON/ShiLtJ m 0.4 1.26   10 0.4 3.16 -0.41
NZB/BlNJ f 0.0 0.0   9 0.0 0.0 -0.44
NZB/BlNJ m 0.0 0.0   9 0.0 0.0 -0.46
NZW/LacJ f 0.0 0.0   8 0.0 0.0 -0.44
NZW/LacJ m 1.6 4.12   10 1.3 2.57 -0.23
PERA/EiJ f 10.2 7.81   8 2.76 0.762 3.0, 24.0 4.78
PERA/EiJ m 12.8 6.55   4 3.28 0.514 3.0, 17.0 1.4
P/J f 0.0 0.0   9 0.0 0.0 -0.44
P/J m 0.556 1.67   9 0.556 3.0 -0.38
PL/J f 0.1 0.316   10 0.1 3.16 -0.38
PL/J m 0.0 0.0   3 0.0 0.0 -0.46
RBF/DnJ f 0.333 1.0   9 0.333 3.0 -0.27
RBF/DnJ m 0.0 0.0   9 0.0 0.0 -0.46
RF/J f 0.2 0.632   10 0.2 3.16 -0.33
RF/J m 0.0 0.0   5 0.0 0.0 -0.46
RIIIS/J f 1.2 1.23   10 0.389 1.02 0.18
RIIIS/J m 13.7 13.4   9 4.48 0.982 3.0, 35.0 1.54
SEA/GnJ f 0.0 0.0   8 0.0 0.0 -0.44
SEA/GnJ m 0.4 1.26   10 0.4 3.16 -0.41
SJL/J f 0.5 0.85   10 0.269 1.7 -0.18
SJL/J m 0.778 2.33   9 0.778 3.0 -0.35
SM/J f 0.0 0.0   7 0.0 0.0 -0.44
SM/J m 0.0 0.0   5 0.0 0.0 -0.46
SPRET/EiJ f 0.0 0.0   7 0.0 0.0 -0.44
SPRET/EiJ m 0.0 0.0   5 0.0 0.0 -0.46
SWR/J f 1.8 2.15   10 0.68 1.19 0.48
SWR/J m 0.625 1.19   8 0.42 1.9 -0.37
WSB/EiJ f 0.5 1.07   8 0.378 2.14 -0.18
WSB/EiJ m 0.167 0.408   6 0.167 2.45 -0.44
YBR/EiJ f 0.0 0.0   3 0.0 0.0 -0.44


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.2 2.5464 5.2006 -4.8006
129S1/SvImJ m 0.0 2.5464 5.0006 -5.0006
A/J f 1.6 2.5464 6.6006 -3.4006
A/J m 1.0 2.5464 6.0006 -4.0006
AKR/J f 0.0 2.6842 5.2711 -5.2711
AKR/J m 0.0 2.6842 5.2711 -5.2711
BALB/cJ f 0.1 2.5464 5.1006 -4.9006
BALB/cJ m 1.1 2.5464 6.1006 -3.9006
BPH/2J f 0.7 2.5464 5.7006 -4.3006
BPH/2J m 0.0 2.6842 5.2711 -5.2711
BPL/1J f 2.5 2.5464 7.5006 -2.5006
BPL/1J m 0.0 2.5464 5.0006 -5.0006
BPN/3J f 0.0 2.5464 5.0006 -5.0006
BPN/3J m 0.6667 2.6842 5.9378 -4.6044
BTBR T+ Itpr3tf/J f 0.0 4.6491 9.1298 -9.1298
BTBR T+ Itpr3tf/J m 0.0 2.5464 5.0006 -5.0006
C3H/HeJ f 0.0 2.6842 5.2711 -5.2711
C3H/HeJ m 11.4 3.6012 18.4719 4.3281
C57BL/10J f 2.5 2.5464 7.5006 -2.5006
C57BL/10J m 38.0 2.5464 43.0006 32.9994
C57BL/6J f 0.2 2.5464 5.2006 -4.8006
C57BL/6J m 4.6667 3.2874 11.1224 -1.7891
C57BLKS/J f 0.1667 3.2874 6.6224 -6.2891
C57BLKS/J m 0.4 3.6012 7.4719 -6.6719
C57BR/cdJ f 0.0 2.6842 5.2711 -5.2711
C57BR/cdJ m 1.0 2.5464 6.0006 -4.0006
C57L/J f 1.6 2.5464 6.6006 -3.4006
C57L/J m 4.8 2.5464 9.8006 -0.2006
C58/J f 7.0 2.5464 12.0006 1.9994
C58/J m 8.0 2.5464 13.0006 2.9994
CAST/EiJ f 0.0 3.6012 7.0719 -7.0719
CAST/EiJ m 12.1111 2.6842 17.3822 6.84
CBA/J f 0.0 2.6842 5.2711 -5.2711
CBA/J m 0.7 2.5464 5.7006 -4.3006
CE/J f 0.0 2.6842 5.2711 -5.2711
CE/J m 0.0 3.2874 6.4557 -6.4557
CZECHII/EiJ f 0.0 3.0436 5.9769 -5.9769
CZECHII/EiJ m 0.5714 3.0436 6.5483 -5.4054
DBA/1J f 0.1 2.5464 5.1006 -4.9006
DBA/1J m 0.0 2.847 5.5908 -5.5908
DBA/2J f 0.3 2.5464 5.3006 -4.7006
DBA/2J m 0.0 2.6842 5.2711 -5.2711
FVB/NJ f 0.0 2.6842 5.2711 -5.2711
FVB/NJ m 7.0 4.6491 16.1298 -2.1298
I/LnJ f 0.0 2.6842 5.2711 -5.2711
I/LnJ m 0.0 2.6842 5.2711 -5.2711
KK/HlJ f 0.0 2.847 5.5908 -5.5908
KK/HlJ m 0.0 2.6842 5.2711 -5.2711
LP/J f 0.1111 2.6842 5.3822 -5.16
LP/J m 0.1111 2.6842 5.3822 -5.16
MOLF/EiJ f 1.0 2.6842 6.2711 -4.2711
MOLF/EiJ m 0.5556 2.6842 5.8267 -4.7155
NOD/ShiLtJ f 3.75 2.847 9.3408 -1.8408
NOD/ShiLtJ m 10.5 3.2874 16.9557 4.0443
NON/ShiLtJ f 0.0 2.6842 5.2711 -5.2711
NON/ShiLtJ m 0.4 2.5464 5.4006 -4.6006
NZB/BlNJ f 0.0 2.6842 5.2711 -5.2711
NZB/BlNJ m 0.0 2.6842 5.2711 -5.2711
NZW/LacJ f 0.0 2.847 5.5908 -5.5908
NZW/LacJ m 1.6 2.5464 6.6006 -3.4006
PERA/EiJ f 10.25 2.847 15.8408 4.6592
PERA/EiJ m 12.75 4.0263 20.6566 4.8434
P/J f 0.0 2.6842 5.2711 -5.2711
P/J m 0.5556 2.6842 5.8267 -4.7155
PL/J f 0.1 2.5464 5.1006 -4.9006
PL/J m 0.0 4.6491 9.1298 -9.1298
RBF/DnJ f 0.3333 2.6842 5.6044 -4.9378
RBF/DnJ m 0.0 2.6842 5.2711 -5.2711
RF/J f 0.2 2.5464 5.2006 -4.8006
RF/J m 0.0 3.6012 7.0719 -7.0719
RIIIS/J f 1.2 2.5464 6.2006 -3.8006
RIIIS/J m 13.6667 2.6842 18.9378 8.3956
SEA/GnJ f 0.0 2.847 5.5908 -5.5908
SEA/GnJ m 0.4 2.5464 5.4006 -4.6006
SJL/J f 0.5 2.5464 5.5006 -4.5006
SJL/J m 0.7778 2.6842 6.0489 -4.4933
SM/J f 0.0 3.0436 5.9769 -5.9769
SM/J m 0.0 3.6012 7.0719 -7.0719
SPRET/EiJ f 0.0 3.0436 5.9769 -5.9769
SPRET/EiJ m 0.0 3.6012 7.0719 -7.0719
SWR/J f 1.8 2.5464 6.8006 -3.2006
SWR/J m 0.625 2.847 6.2158 -4.9658
WSB/EiJ f 0.5 2.847 6.0908 -5.0908
WSB/EiJ m 0.1667 3.2874 6.6224 -6.2891


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.1 1.8006 3.636 -3.436
A/J both 1.3 1.8006 4.836 -2.236
AKR/J both 0.0 1.898 3.7272 -3.7272
BALB/cJ both 0.6 1.8006 4.136 -2.936
BPH/2J both 0.35 1.8499 3.9829 -3.2829
BPL/1J both 1.25 1.8006 4.786 -2.286
BPN/3J both 0.3333 1.8499 3.9662 -3.2995
BTBR T+ Itpr3tf/J both 0.0 2.6504 5.2048 -5.2048
C3H/HeJ both 5.7 2.2457 10.1101 1.2899
C57BL/10J both 20.25 1.8006 23.786 16.714
C57BL/6J both 2.4333 2.0791 6.5163 -1.6496
C57BLKS/J both 0.2833 2.438 5.071 -4.5044
C57BR/cdJ both 0.5 1.8499 4.1329 -3.1329
C57L/J both 3.2 1.8006 6.736 -0.336
C58/J both 7.5 1.8006 11.036 3.964
CAST/EiJ both 6.0556 2.2457 10.4657 1.6454
CBA/J both 0.35 1.8499 3.9829 -3.2829
CE/J both 0.0 2.122 4.1672 -4.1672
CZECHII/EiJ both 0.2857 2.1521 4.512 -3.9406
DBA/1J both 0.05 1.9098 3.8005 -3.7005
DBA/2J both 0.15 1.8499 3.7829 -3.4829
FVB/NJ both 3.5 2.6842 8.7711 -1.7711
I/LnJ both 0.0 1.898 3.7272 -3.7272
KK/HlJ both 0.0 1.9564 3.8419 -3.8419
LP/J both 0.1111 1.898 3.8383 -3.6161
MOLF/EiJ both 0.7778 1.898 4.505 -2.9494
NOD/ShiLtJ both 7.125 2.1744 11.3951 2.8549
NON/ShiLtJ both 0.2 1.8499 3.8329 -3.4329
NZB/BlNJ both 0.0 1.898 3.7272 -3.7272
NZW/LacJ both 0.8 1.9098 4.5505 -2.9505
PERA/EiJ both 11.5 2.4656 16.3418 6.6582
P/J both 0.2778 1.898 4.005 -3.4494
PL/J both 0.05 2.6504 5.2548 -5.1548
RBF/DnJ both 0.1667 1.898 3.8939 -3.5606
RF/J both 0.1 2.2053 4.4306 -4.2306
RIIIS/J both 7.4333 1.8499 11.0662 3.8005
SEA/GnJ both 0.2 1.9098 3.9505 -3.5505
SJL/J both 0.6389 1.8499 4.2717 -2.994
SM/J both 0.0 2.3575 4.6297 -4.6297
SPRET/EiJ both 0.0 2.3575 4.6297 -4.6297
SWR/J both 1.2125 1.9098 4.963 -2.538
WSB/EiJ both 0.3333 2.1744 4.6034 -3.9367




  GWAS USING LINEAR MIXED MODELS