Project measure / variable:   Ackert1   bone_area_M06

ID, description, units MPD:25021   bone_area_M06   whole body bone area, head excluded   [cm2]  at age 6mo  
Data set, strains Ackert1   inbred   32 strains     sex: both     age: 26wks
Procedure DXA
Ontology mappings

  STRAIN COMPARISON PLOT
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Ackert1 - whole body bone area, head excluded at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested31 strains30 strains
Mean of the strain means10.5   cm2 10.8   cm2
Median of the strain means10.2   cm2 10.7   cm2
SD of the strain means± 1.46 ± 1.23
Coefficient of variation (CV)0.139 0.114
Min–max range of strain means7.31   –   14.0   cm2 8.77   –   13.4   cm2
Mean sample size per strain7.0   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 9.2239 9.2239 15.5431 0.0001
strain 30 628.8074 20.9602 35.32 < 0.0001
sex:strain 30 141.0668 4.7022 7.9237 < 0.0001
Residuals 344 204.1428 0.5934


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 11.6 0.467   8 0.165 0.0403 10.9, 12.1 0.75
129S1/SvImJ m 12.6 1.36   7 0.513 0.107 10.6, 14.5 1.45
A/J f 8.82 0.702   8 0.248 0.0795 8.03, 10.1 -1.15
A/J m 9.8 0.828   8 0.293 0.0845 8.56, 11.0 -0.83
AKR/J f 10.0 0.724   6 0.295 0.0721 8.69, 10.8 -0.34
AKR/J m 11.3 0.698   5 0.312 0.0616 10.4, 12.3 0.39
BALB/cByJ f 11.9 0.836   6 0.341 0.0704 11.1, 12.9 0.96
BALB/cByJ m 11.2 1.2   6 0.492 0.108 9.72, 13.0 0.31
BTBR T+ Itpr3tf/J f 11.0 0.62   5 0.277 0.0564 10.2, 11.6 0.34
BTBR T+ Itpr3tf/J m 12.2 0.699   7 0.264 0.0572 11.7, 13.7 1.13
BUB/BnJ f 14.0 1.31   8 0.464 0.0939 11.6, 15.8 2.4
BUB/BnJ m 13.4 0.624   4 0.312 0.0464 12.8, 14.2 2.1
C3H/HeJ f 12.8 0.566   8 0.2 0.044 12.2, 13.9 1.58
C3H/HeJ m 12.1 1.3   6 0.53 0.107 10.2, 13.8 1.04
C57BL/10J f 10.2 0.585   8 0.207 0.0573 9.63, 10.8 -0.21
C57BL/10J m 11.2 0.388   6 0.158 0.0346 10.7, 11.7 0.31
C57BL/6J f 9.96 0.628   8 0.222 0.0631 9.3, 11.0 -0.37
C57BL/6J m 12.3 1.16   8 0.411 0.0944 10.6, 13.8 1.21
C57BLKS/J f 9.53 0.339   8 0.12 0.0356 9.0, 9.95 -0.67
C57BLKS/J m 10.3 0.454   8 0.16 0.0442 9.77, 11.2 -0.42
C57BR/cdJ f 12.5 0.996   7 0.376 0.0796 11.7, 14.1 1.37
C57BR/cdJ m 10.4 0.796   6 0.325 0.0766 9.44, 11.2 -0.34
C57L/J f 11.5 1.11   7 0.418 0.0959 10.6, 13.8 0.69
C57L/J m 10.2 0.55   5 0.246 0.054 9.61, 11.1 -0.5
CAST/EiJ f 8.96 0.746   6 0.305 0.0833 7.81, 9.94 -1.06
CAST/EiJ m 9.32 0.676   7 0.256 0.0726 8.7, 10.4 -1.22
CBA/J f 10.5 0.85   8 0.3 0.0809 9.73, 11.9 0.0
CBA/J m 10.9 0.275   4 0.138 0.0253 10.6, 11.2 0.07
DBA/2J f 9.13 0.584   5 0.261 0.064 8.27, 9.72 -0.94
DBA/2J m 12.2 1.21   7 0.456 0.0986 10.5, 13.8 1.13
FVB/NJ f 10.6 1.19   8 0.422 0.113 9.32, 13.0 0.07
FVB/NJ m 11.7 0.812   6 0.331 0.0692 10.8, 12.9 0.72
KK/HlJ f 10.4 0.391   4 0.195 0.0377 9.91, 10.7 -0.07
KK/HlJ m 10.1 0.746   7 0.282 0.0736 9.18, 11.0 -0.58
LP/J f 10.1 0.436   6 0.178 0.0431 9.48, 10.6 -0.28
LP/J m 10.1 0.517   8 0.183 0.0512 9.48, 11.2 -0.58
MOLF/EiJ f 9.31 0.458   7 0.173 0.0492 8.79, 9.96 -0.82
MOLF/EiJ m 9.23 0.189   7 0.0714 0.0205 8.94, 9.53 -1.29
MRL/MpJ f 11.5 0.4   3 0.231 0.0348 11.1, 11.9 0.69
MRL/MpJ m 12.9 0.54   7 0.204 0.0418 12.3, 13.8 1.69
NOD.B10Sn-H2b/J f 13.6 0.468   8 0.166 0.0345 12.9, 14.2 2.13
NON/ShiLtJ f 10.2 0.435   8 0.154 0.0428 9.59, 10.8 -0.21
NON/ShiLtJ m 11.0 0.661   7 0.25 0.0601 10.1, 12.2 0.15
NZW/LacJ f 10.0 0.636   8 0.225 0.0633 9.11, 11.0 -0.34
NZW/LacJ m 11.7 0.921   5 0.412 0.0784 10.5, 12.9 0.72
P/J f 11.0 0.683   6 0.279 0.0618 10.1, 11.8 0.34
P/J m 10.6 0.896   6 0.366 0.0842 9.89, 12.2 -0.18
PL/J f 9.1 0.557   8 0.197 0.0611 8.46, 10.2 -0.96
PL/J m 9.22 0.404   8 0.143 0.0438 8.43, 9.74 -1.3
PWD/PhJ f 9.96 0.337   5 0.151 0.0339 9.5, 10.4 -0.37
PWD/PhJ m 9.84 0.584   4 0.292 0.0593 8.97, 10.2 -0.79
RIIIS/J f 9.89 0.607   8 0.215 0.0614 9.21, 10.9 -0.42
RIIIS/J m 9.03 0.578   6 0.236 0.064 8.49, 9.91 -1.45
SJL/J f 11.1 1.65   8 0.582 0.148 8.9, 14.0 0.41
SJL/J m 9.86 0.609   6 0.248 0.0617 9.13, 10.8 -0.78
SM/J f 7.31 0.568   8 0.201 0.0778 6.35, 7.89 -2.19
SM/J m 10.2 0.782   8 0.276 0.0766 8.55, 11.1 -0.5
SWR/J f 10.3 0.479   6 0.196 0.0465 9.6, 10.9 -0.14
SWR/J m 10.8 0.417   6 0.17 0.0385 10.3, 11.4 -0.01
WSB/EiJ f 8.76 0.66   6 0.27 0.0754 7.52, 9.44 -1.2
WSB/EiJ m 8.77 0.331   6 0.135 0.0377 8.42, 9.25 -1.66


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 11.5875 0.2724 12.1232 11.0518
129S1/SvImJ m 12.6429 0.2912 13.2155 12.0702
A/J f 8.8237 0.2724 9.3594 8.2881
A/J m 9.7962 0.2724 10.3319 9.2606
AKR/J f 10.0333 0.3145 10.6519 9.4148
AKR/J m 11.32 0.3445 11.9976 10.6424
BALB/cByJ f 11.8667 0.3145 12.4852 11.2481
BALB/cByJ m 11.1867 0.3145 11.8052 10.5681
BTBR T+ Itpr3tf/J f 11.0 0.3445 11.6776 10.3224
BTBR T+ Itpr3tf/J m 12.2143 0.2912 12.787 11.6416
BUB/BnJ f 13.9625 0.2724 14.4982 13.4268
BUB/BnJ m 13.45 0.3852 14.2076 12.6924
C3H/HeJ f 12.85 0.2724 13.3857 12.3143
C3H/HeJ m 12.1 0.3145 12.7186 11.4814
C57BL/10J f 10.205 0.2724 10.7407 9.6693
C57BL/10J m 11.2333 0.3145 11.8519 10.6148
C57BL/6J f 9.955 0.2724 10.4907 9.4193
C57BL/6J m 12.325 0.2724 12.8607 11.7893
C57BLKS/J f 9.5325 0.2724 10.0682 8.9968
C57BLKS/J m 10.26 0.2724 10.7957 9.7243
C57BR/cdJ f 12.5143 0.2912 13.087 11.9416
C57BR/cdJ m 10.39 0.3145 11.0086 9.7714
C57L/J f 11.5286 0.2912 12.1013 10.9559
C57L/J m 10.2 0.3445 10.8776 9.5224
CAST/EiJ f 8.9567 0.3145 9.5752 8.3381
CAST/EiJ m 9.3214 0.2912 9.8941 8.7487
CBA/J f 10.51 0.2724 11.0457 9.9743
CBA/J m 10.875 0.3852 11.6326 10.1174
DBA/2J f 9.13 0.3445 9.8076 8.4524
DBA/2J m 12.2429 0.2912 12.8155 11.6702
FVB/NJ f 10.5537 0.2724 11.0894 10.0181
FVB/NJ m 11.7333 0.3145 12.3519 11.1148
KK/HlJ f 10.3775 0.3852 11.1351 9.6199
KK/HlJ m 10.1314 0.2912 10.7041 9.5587
LP/J f 10.1183 0.3145 10.7369 9.4998
LP/J m 10.0975 0.2724 10.6332 9.5618
MOLF/EiJ f 9.3057 0.2912 9.8784 8.733
MOLF/EiJ m 9.23 0.2912 9.8027 8.6573
MRL/MpJ f 11.5 0.4448 12.3748 10.6252
MRL/MpJ m 12.9143 0.2912 13.487 12.3416
NOD.B10Sn-H2b/J f 13.575 0.2724 14.1107 13.0393
NOD.B10Sn-H2b/J m 13.55 0.5447 14.6214 12.4786
NON/ShiLtJ f 10.165 0.2724 10.7007 9.6293
NON/ShiLtJ m 11.0 0.2912 11.5727 10.4273
NZW/LacJ f 10.0362 0.2724 10.5719 9.5006
NZW/LacJ m 11.74 0.3445 12.4176 11.0624
P/J f 11.05 0.3145 11.6686 10.4314
P/J m 10.64 0.3145 11.2586 10.0214
PL/J f 9.1037 0.2724 9.6394 8.5681
PL/J m 9.2237 0.2724 9.7594 8.6881
PWD/PhJ f 9.956 0.3445 10.6336 9.2784
PWD/PhJ m 9.8425 0.3852 10.6001 9.0849
RIIIS/J f 9.8887 0.2724 10.4244 9.3531
RIIIS/J m 9.0317 0.3145 9.6502 8.4131
SJL/J f 11.1125 0.2724 11.6482 10.5768
SJL/J m 9.8567 0.3145 10.4752 9.2381
SM/J f 7.3088 0.2724 7.8444 6.7731
SM/J m 10.205 0.2724 10.7407 9.6693
SWR/J f 10.3167 0.3145 10.9352 9.6981
SWR/J m 10.8167 0.3145 11.4352 10.1981
WSB/EiJ f 8.755 0.3145 9.3736 8.1364
WSB/EiJ m 8.77 0.3145 9.3886 8.1514


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 12.1152 0.1993 12.5073 11.7231
A/J both 9.31 0.1926 9.6888 8.9312
AKR/J both 10.6767 0.2332 11.1354 10.2179
BALB/cByJ both 11.5267 0.2224 11.9641 11.0893
BTBR T+ Itpr3tf/J both 11.6071 0.2255 12.0507 11.1635
BUB/BnJ both 13.7062 0.2359 14.1702 13.2423
C3H/HeJ both 12.475 0.208 12.8841 12.0659
C57BL/10J both 10.7192 0.208 11.1283 10.31
C57BL/6J both 11.14 0.1926 11.5188 10.7612
C57BLKS/J both 9.8962 0.1926 10.275 9.5175
C57BR/cdJ both 11.4521 0.2143 11.8736 11.0307
C57L/J both 10.8643 0.2255 11.3079 10.4207
CAST/EiJ both 9.139 0.2143 9.5605 8.7176
CBA/J both 10.6925 0.2359 11.1564 10.2286
DBA/2J both 10.6864 0.2255 11.13 10.2428
FVB/NJ both 11.1435 0.208 11.5527 10.7344
KK/HlJ both 10.2545 0.2414 10.7293 9.7796
LP/J both 10.1079 0.208 10.5171 9.6988
MOLF/EiJ both 9.2679 0.2059 9.6728 8.8629
MRL/MpJ both 12.2071 0.2658 12.7299 11.6844
NOD.B10Sn-H2b/J both 13.5625 0.3045 14.1614 12.9636
NON/ShiLtJ both 10.5825 0.1993 10.9746 10.1904
NZW/LacJ both 10.8881 0.2196 11.32 10.4562
P/J both 10.845 0.2224 11.2824 10.4076
PL/J both 9.1637 0.1926 9.5425 8.785
PWD/PhJ both 9.8992 0.2584 10.4075 9.391
RIIIS/J both 9.4602 0.208 9.8694 9.0511
SJL/J both 10.4846 0.208 10.8937 10.0754
SM/J both 8.7569 0.1926 9.1357 8.3781
SWR/J both 10.5667 0.2224 11.0041 10.1293
WSB/EiJ both 8.7625 0.2224 9.1999 8.3251




  GWAS USING LINEAR MIXED MODELS