Project measure / variable:   Seburn2   grip_strength_M24

ID, description, units MPD:24804   grip_strength_M24   grip strength, peak tension over 3 trials   [g]  at age 24mo  
Data set, strains Seburn2   inbred   28 strains     sex: both     age: 104wks
Procedure grip strength
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  STRAIN COMPARISON PLOT
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Seburn2 - grip strength, peak tension over 3 trials at age 24mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested26 strains26 strains
Mean of the strain means96.3   g 101   g
Median of the strain means98.6   g 101   g
SD of the strain means± 17.8 ± 15.2
Coefficient of variation (CV)0.185 0.150
Min–max range of strain means58.6   –   132   g 77.0   –   142   g
Mean sample size per strain7.0   mice 6.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1393.9031 1393.9031 7.6962 0.0059
strain 23 54709.5157 2378.6746 13.1334 < 0.0001
sex:strain 23 16008.9081 696.0395 3.8431 < 0.0001
Residuals 291 52704.8635 181.1164


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 114.0 5.29   7 2.0 0.0462 110.0, 123.0 0.99
129S1/SvImJ m 110.0 4.36   6 1.78 0.0397 104.0, 117.0 0.56
A/J f 94.0 18.5   11 5.58 0.197 55.3, 119.0 -0.13
A/J m 106.0 10.9   4 5.46 0.103 94.7, 117.0 0.3
BALB/cByJ f 129.0 5.43   7 2.05 0.042 119.0, 137.0 1.83
BALB/cByJ m 127.0 16.0   7 6.04 0.126 99.3, 143.0 1.68
BTBR T+ Itpr3tf/J f 132.0 13.2   3 7.64 0.1 117.0, 142.0 2.0
BTBR T+ Itpr3tf/J m 114.0 9.26   7 3.5 0.0809 98.3, 129.0 0.82
BUB/BnJ f 85.9 12.0   5 5.36 0.14 76.7, 106.0 -0.58
BUB/BnJ m 111.0 3.98   6 1.63 0.036 103.0, 114.0 0.63
C3H/HeJ f 94.0 10.3   8 3.65 0.11 79.3, 107.0 -0.13
C3H/HeJ m 88.5 13.1   7 4.94 0.148 64.0, 100.0 -0.85
C57BL/10J f 96.0 18.9   8 6.67 0.197 61.7, 127.0 -0.02
C57BL/10J m 86.6 23.6   7 8.91 0.272 51.0, 115.0 -0.98
C57BL/6J f 94.8 9.06   9 3.02 0.0956 78.7, 108.0 -0.09
C57BL/6J m 103.0 9.3   11 2.8 0.0901 84.3, 117.0 0.1
C57BLKS/J f 99.7 5.52   8 1.95 0.0553 91.0, 106.0 0.19
C57BLKS/J m 95.9 10.6   11 3.19 0.11 81.7, 115.0 -0.37
C57BR/cdJ f 107.0 15.9   8 5.63 0.149 92.0, 128.0 0.6
C57BR/cdJ m 105.0 21.5   7 8.14 0.204 57.3, 117.0 0.23
C57L/J f 104.0 22.6   8 8.0 0.219 81.3, 139.0 0.43
C57L/J m 103.0 9.1   7 3.44 0.0885 89.0, 115.0 0.1
CAST/EiJ f 58.6 13.9   3 8.02 0.237 43.0, 69.7 -2.12
CBA/J f 100.0 8.4   8 2.97 0.0839 92.3, 117.0 0.21
CBA/J m 102.0 6.63   7 2.51 0.0649 91.3, 108.0 0.03
DBA/2J f 99.8 6.96   7 2.63 0.0698 93.3, 112.0 0.19
DBA/2J m 81.7 17.8   8 6.3 0.218 67.3, 112.0 -1.3
FVB/NJ f 83.5 15.8   8 5.59 0.189 61.3, 102.0 -0.72
FVB/NJ m 97.1 11.0   8 3.89 0.113 78.0, 115.0 -0.29
LP/J f 121.0 10.9   6 4.47 0.0902 109.0, 140.0 1.38
LP/J m 99.8 22.6   7 8.55 0.227 53.3, 119.0 -0.11
MRL/MpJ m 125.0 0.0   1   0.0 0.0 125.0, 125.0 1.55
NOD.B10Sn-H2b/J f 105.0 8.88   7 3.36 0.0846 93.3, 119.0 0.49
NOD.B10Sn-H2b/J m 142.0 8.94   6 3.65 0.0632 130.0, 152.0 2.66
NON/ShiLtJ f 79.3 18.9   8 6.68 0.238 49.3, 101.0 -0.96
NON/ShiLtJ m 109.0 11.2   6 4.57 0.103 88.3, 121.0 0.49
NZW/LacJ f 108.0 10.1   7 3.83 0.0934 94.7, 119.0 0.65
NZW/LacJ m 98.5 4.97   6 2.03 0.0504 90.0, 103.0 -0.2
P/J f 104.0 12.3   7 4.64 0.118 87.7, 124.0 0.43
PL/J m 82.3 0.0   1   0.0 0.0 82.3, 82.3 -1.26
PWD/PhJ f 67.7 19.6   7 7.42 0.29 36.3, 100.0 -1.61
PWD/PhJ m 77.0 14.0   7 5.3 0.182 64.7, 98.3 -1.61
RIIIS/J f 97.5 10.7   6 4.38 0.11 85.7, 113.0 0.07
RIIIS/J m 111.0 14.1   8 4.97 0.127 91.7, 129.0 0.63
SJL/J f 68.5 12.9   6 5.27 0.188 56.0, 90.7 -1.56
SJL/J m 85.7 7.74   4 3.87 0.0904 75.7, 94.0 -1.04
SM/J f 101.0 10.7   7 4.04 0.106 89.0, 122.0 0.26
SM/J m 98.6 9.57   7 3.62 0.0971 89.0, 110.0 -0.19
SWR/J f 74.3 8.46   6 3.45 0.114 67.3, 88.3 -1.24
SWR/J m 83.2 17.7   7 6.7 0.213 48.0, 104.0 -1.2
WSB/EiJ f 86.0 17.7   7 6.7 0.206 57.7, 104.0 -0.58
WSB/EiJ m 95.8 6.81   6 2.78 0.0711 87.0, 104.0 -0.37


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 114.4286 5.0866 124.4398 104.4173
129S1/SvImJ m 109.8333 5.4942 120.6467 99.02
A/J f 94.0091 4.0577 101.9953 86.0229
A/J m 106.25 6.729 119.4936 93.0064
BALB/cByJ f 129.1429 5.0866 139.1541 119.1316
BALB/cByJ m 126.9 5.0866 136.9112 116.8888
BTBR T+ Itpr3tf/J f 132.0 7.77 147.2924 116.7076
BTBR T+ Itpr3tf/J m 114.4714 5.0866 124.4827 104.4602
BUB/BnJ f 85.94 6.0186 97.7855 74.0945
BUB/BnJ m 110.6667 5.4942 121.48 99.8533
C3H/HeJ f 94.0125 4.7581 103.3772 84.6478
C3H/HeJ m 88.5286 5.0866 98.5398 78.5173
C57BL/10J f 95.9625 4.7581 105.3272 86.5978
C57BL/10J m 86.6143 5.0866 96.6255 76.603
C57BL/6J f 94.7556 4.486 103.5846 85.9265
C57BL/6J m 103.1818 4.0577 111.168 95.1956
C57BLKS/J f 99.6625 4.7581 109.0272 90.2978
C57BLKS/J m 95.8909 4.0577 103.8771 87.9047
C57BR/cdJ f 107.2125 4.7581 116.5772 97.8478
C57BR/cdJ m 105.4714 5.0866 115.4827 95.4602
C57L/J f 103.5375 4.7581 112.9022 94.1728
C57L/J m 102.8571 5.0866 112.8684 92.8459
CBA/J f 100.1125 4.7581 109.4772 90.7478
CBA/J m 102.0857 5.0866 112.097 92.0745
DBA/2J f 99.7714 5.0866 109.7827 89.7602
DBA/2J m 81.7 4.7581 91.0647 72.3353
FVB/NJ f 83.5375 4.7581 92.9022 74.1728
FVB/NJ m 97.125 4.7581 106.4897 87.7603
LP/J f 121.3333 5.4942 132.1467 110.52
LP/J m 99.7571 5.0866 109.7684 89.7459
NOD.B10Sn-H2b/J f 104.9429 5.0866 114.9541 94.9316
NOD.B10Sn-H2b/J m 141.5 5.4942 152.3134 130.6866
NON/ShiLtJ f 79.275 4.7581 88.6397 69.9103
NON/ShiLtJ m 108.55 5.4942 119.3634 97.7366
NZW/LacJ f 108.4857 5.0866 118.497 98.4745
NZW/LacJ m 98.55 5.4942 109.3634 87.7366
PWD/PhJ f 67.7429 5.0866 77.7541 57.7316
PWD/PhJ m 77.0429 5.0866 87.0541 67.0316
RIIIS/J f 97.5 5.4942 108.3134 86.6866
RIIIS/J m 111.05 4.7581 120.4147 101.6853
SJL/J f 68.45 5.4942 79.2634 57.6366
SJL/J m 85.675 6.729 98.9186 72.4314
SM/J f 101.3286 5.0866 111.3398 91.3173
SM/J m 98.5714 5.0866 108.5827 88.5602
SWR/J f 74.3333 5.4942 85.1467 63.52
SWR/J m 83.2429 5.0866 93.2541 73.2316
WSB/EiJ f 86.0143 5.0866 96.0255 76.003
WSB/EiJ m 95.7667 5.4942 106.58 84.9533


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 112.131 3.7437 119.499 104.7629
A/J both 100.1295 3.9289 107.8622 92.3969
BALB/cByJ both 128.0214 3.5968 135.1004 120.9424
BTBR T+ Itpr3tf/J both 123.2357 4.6434 132.3747 114.0967
BUB/BnJ both 98.3033 4.0746 106.3227 90.2839
C3H/HeJ both 91.2705 3.4826 98.1248 84.4163
C57BL/10J both 91.2884 3.4826 98.1426 84.4342
C57BL/6J both 98.9687 3.0244 104.9213 93.0161
C57BLKS/J both 97.7767 3.1267 103.9305 91.6229
C57BR/cdJ both 106.342 3.4826 113.1962 99.4877
C57L/J both 103.1973 3.4826 110.0515 96.3431
CBA/J both 101.0991 3.4826 107.9533 94.2449
DBA/2J both 90.7357 3.4826 97.5899 83.8815
FVB/NJ both 90.3313 3.3645 96.9531 83.7094
LP/J both 110.5452 3.7437 117.9133 103.1772
NOD.B10Sn-H2b/J both 123.2214 3.7437 130.5895 115.8534
NON/ShiLtJ both 93.9125 3.6341 101.0649 86.7601
NZW/LacJ both 103.5179 3.7437 110.8859 96.1498
PWD/PhJ both 72.3929 3.5968 79.4719 65.3138
RIIIS/J both 104.275 3.6341 111.4274 97.1226
SJL/J both 77.0625 4.3435 85.6112 68.5138
SM/J both 99.95 3.5968 107.029 92.871
SWR/J both 78.7881 3.7437 86.1562 71.42
WSB/EiJ both 90.8905 3.7437 98.2586 83.5224




  GWAS USING LINEAR MIXED MODELS