MPD: Data set: Seburn2

Wooley CM, Xing S, Burgess RW, Cox GA, Seburn KL. Age, experience and genetic background influence treadmill walking in mice. Physiol Behav. 2009 Feb 16;96(2):350-6Epub 2008 Nov 6. PubMed 19027767 FullText

Seburn2 downloads
• Download Seburn2 project data set animal data, as uploaded
• Download Seburn2 animal data matrix with factor-related expansion applied as necessary
• Download Seburn2 strain means, SD, N, etc. one row per strain/sex/measure
• Seburn2 supplementary data

Ontology terms mapped to Seburn2 measures:

MA:0000025 forelimb
MA:0000026 hindlimb
MA:0000615 forelimb muscle
MP:0001406 abnormal gait
MP:0001515 abnormal grip strength
MP:0012690 abnormal stride length
VT:0000004 forelimb conformation trait
VT:0000016 hindlimb conformation trait
VT:0004262 physical strength trait
VT:0010080 skeletal muscle physiology trait

Investigators	Kevin L Seburn The Jackson Laboratory, Bar Harbor, ME Shuqin Xing The Jackson Laboratory, Bar Harbor, ME Robert W Burgess The Jackson Laboratory, Bar Harbor, ME
Participants	Schultz D, Godfrey D
Contact	Kevin L Seburn kevins@jax.org Lab web site
Affiliated Center	JAX Nathan Shock Aging Center
Acknowledgements	Funding provided by NIH AG025707 (NIA Nathan Shock Center for Aging Research); The Ellison Medical Foundation
Project type	Phenotype strain survey data set
MPD identifiers	Seburn2 MPD:248
Data changelog	3 updates/corrections. Initial release date: 07/2008.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Grip strength followed one cohort of animals. Gait analysis used 2 different cohorts (6mo, 18mo). In the gait analysis, 7 strains were measured at age 6 mo. and 3 strains were measured at age 18 mo.

Procedures conducted:

• grip strength		Peak tension. 3 trials. Aging study, 6mo, 12mo, 18mo, 24mo.
• gait analysis		Aging study, 6mo, 18mo.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Sample Size (Avg)
Seburn2:1	Seburn2	grip strength	(none)	grip strength, peak tension over 3 trials [g] grip_strength 24801 6mo 12mo 18mo 24mo	inbred	32	both	N=8

Seburn2:5	Seburn2	gait analysis	(none)	stance phase, mean time that either front paw is in contact with surface during a step [ms] stance_F 24805 6mo 18mo	inbred	7	both	N=6

Seburn2:9	Seburn2	gait analysis	(none)	swing phase, mean time that either front paw is not in contact with the surface during a step [ms] swing_F 24809 6mo 18mo	inbred	7	both	N=6

Seburn2:13	Seburn2	gait analysis	(none)	stride time, mean time between consecutive front paw contacts [ms] stride_F 24813 6mo 18mo	inbred	7	both	N=6

Seburn2:17	Seburn2	gait analysis	(none)	stance-to-stride ratio, mean for front paws [ratio] stance_stride_F 24817 6mo 18mo	inbred	7	both	N=6

Seburn2:21	Seburn2	gait analysis	(none)	swing-to-stride ratio, mean for front paws [ratio] swing_stride_F 24821 6mo 18mo	inbred	7	both	N=6

Seburn2:25	Seburn2	gait analysis	(none)	stride length, mean distance between consecutive front paw contacts [mm] stride_length_F 24825 6mo 18mo	inbred	7	both	N=6

Seburn2:33	Seburn2	gait analysis	(none)	front track width, mean distance between front paws at midpoint of stance phase [mm] track_width_F 24833 6mo 18mo	inbred	7	both	N=6

Seburn2:39	Seburn2	gait analysis	(none)	stride frequency, mean number of steps per second for front paws [Hz] stride_freq_F 24839 6mo 18mo	inbred	7	both	N=6

Seburn2:45	Seburn2	gait analysis	(none)	stance phase, mean time that either rear paw is in contact with surface during a step [ms] stance_R 24845 6mo 18mo	inbred	7	both	N=6

Seburn2:49	Seburn2	gait analysis	(none)	swing phase, mean time that either rear paw is not in contact with the surface during a step [ms] swing_R 24849 6mo 18mo	inbred	7	both	N=6

Seburn2:53	Seburn2	gait analysis	(none)	stride time, mean time between consecutive rear paw contacts [ms] stride_R 24853 6mo 18mo	inbred	7	both	N=6

Seburn2:57	Seburn2	gait analysis	(none)	stance-to-stride ratio, mean for rear paws [ratio] stance_stride_R 24857 6mo 18mo	inbred	7	both	N=6

Seburn2:61	Seburn2	gait analysis	(none)	swing-to-stride ratio, mean for rear paws [ratio] swing_stride_R 24861 6mo 18mo	inbred	7	both	N=6

Seburn2:65	Seburn2	gait analysis	(none)	stride length, mean distance between consecutive rear paw contacts [mm] stride_length_R 24865 6mo 18mo	inbred	7	both	N=6

Seburn2:73	Seburn2	gait analysis	(none)	front track width, mean distance between rear paws at midpoint of stance phase [mm] rear_track_width_R 24873 6mo 18mo	inbred	7	both	N=6

Seburn2:79	Seburn2	gait analysis	(none)	stride frequency, mean number of steps per second for rear paws [Hz] stride_freq_R 24879 6mo 18mo	inbred	7	both	N=6

Seburn2: Aging study: Grip strength and gait analysis in 32 inbred strains of mice (2008)