Project measure / variable:   Cheverud1   TG_hifat

ID, description, units MPD:17894   TG_hifat   triglycerides (serum TG, 4h fast)   [mg/dL]  high-fat diet  
high-fat diet study
Data set, strains Cheverud1   LGXSM w/par   17 strains     sex: both     age: 20-30wks
Procedure lipid profile
Ontology mappings

  STRAIN COMPARISON PLOT
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Cheverud1 - triglycerides (serum TG, 4h fast) high-fat diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested12 strains17 strains
Mean of the strain means101   mg/dL 95.9   mg/dL
Median of the strain means95.5   mg/dL 77.5   mg/dL
SD of the strain means± 24.3 ± 39.9
Coefficient of variation (CV)0.242 0.416
Min–max range of strain means74.0   –   147   mg/dL 42.2   –   193   mg/dL
Mean sample size per strain8.3   mice 7.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3211.4885 3211.4885 1.1335 0.2884
strain 11 131674.3811 11970.3983 4.2248 < 0.0001
sex:strain 11 23449.0239 2131.7294 0.7524 0.687
Residuals 185 524169.4168 2833.3482


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
LGXSM10 f 105.0 38.9   9 13.0 0.371 36.4, 156.0 0.18
LGXSM10 m 122.0 107.0   10 33.8 0.88 17.5, 410.0 0.66
LGXSM15 f 97.8 37.5   9 12.5 0.384 59.8, 165.0 -0.11
LGXSM15 m 70.5 27.0   11 8.14 0.383 22.4, 108.0 -0.64
LGXSM18 f 93.0 35.1   9 11.7 0.377 27.9, 141.0 -0.31
LGXSM18 m 68.6 59.6   7 22.5 0.87 23.1, 191.0 -0.68
LGXSM19 f 74.0 29.6   8 10.5 0.401 22.8, 123.0 -1.09
LGXSM19 m 42.2 28.8   8 10.2 0.682 6.29, 90.7 -1.34
LGXSM20 f 133.0 41.2   5 18.4 0.31 93.4, 181.0 1.33
LGXSM20 m 168.0 141.0   6 57.8 0.844 60.7, 428.0 1.81
LGXSM22 f 74.6 25.0   13 6.95 0.336 38.4, 111.0 -1.07
LGXSM22 m 77.5 44.3   12 12.8 0.571 7.09, 165.0 -0.46
LGXSM23 f 76.8 38.8   8 13.7 0.505 34.4, 159.0 -0.98
LGXSM23 m 71.7 49.5   10 15.6 0.69 5.48, 138.0 -0.61
LGXSM31 m 98.4 72.4   4 36.2 0.736 53.6, 206.0 0.06
LGXSM33 f 76.5 30.2   10 9.56 0.395 24.8, 126.0 -0.99
LGXSM33 m 73.7 25.3   12 7.3 0.343 43.7, 128.0 -0.56
LGXSM38 f 121.0 31.5   7 11.9 0.26 68.2, 167.0 0.84
LGXSM38 m 66.8 21.5   7 8.12 0.322 27.9, 100.0 -0.73
LGXSM39 m 61.1 29.2   3 16.8 0.477 27.4, 78.3 -0.87
LGXSM4 f 93.3 46.0   7 17.4 0.493 37.4, 155.0 -0.3
LGXSM4 m 106.0 58.7   6 24.0 0.554 19.5, 195.0 0.25
LGXSM45 m 65.0 26.3   3 15.2 0.404 44.9, 94.7 -0.77
LGXSM46 f 147.0 57.2   8 20.2 0.388 87.4, 272.0 1.91
LGXSM46 m 128.0 78.6   10 24.9 0.616 39.0, 249.0 0.81
LGXSM48 m 109.0 52.2   8 18.5 0.477 64.3, 227.0 0.33
LGXSM5 f 115.0 49.6   8 17.5 0.433 59.3, 204.0 0.59
LGXSM5 m 108.0 60.6   9 20.2 0.56 42.5, 236.0 0.3
SM/J m 193.0 95.8   6 39.1 0.497 72.8, 331.0 2.43


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
LGXSM10 f 104.6889 17.7431 139.6937 69.6841
LGXSM10 m 121.57 16.8326 154.7784 88.3616
LGXSM15 f 97.7778 17.7431 132.7825 62.773
LGXSM15 m 70.4909 16.0492 102.1539 38.8279
LGXSM18 f 92.9667 17.7431 127.9714 57.9619
LGXSM18 m 68.5714 20.1187 108.2631 28.8798
LGXSM19 f 73.9625 18.8194 111.0907 36.8343
LGXSM19 m 42.2238 18.8194 79.3519 5.0956
LGXSM20 f 133.08 23.8048 180.0438 86.1162
LGXSM20 m 167.6833 21.7307 210.5552 124.8114
LGXSM22 f 74.5923 14.7631 103.718 45.4666
LGXSM22 m 77.5325 15.3659 107.8475 47.2175
LGXSM23 f 76.825 18.8194 113.9532 39.6968
LGXSM23 m 71.698 16.8326 104.9064 38.4896
LGXSM33 f 76.53 16.8326 109.7384 43.3216
LGXSM33 m 73.6833 15.3659 103.9983 43.3683
LGXSM38 f 121.3143 20.1187 161.006 81.6226
LGXSM38 m 66.8429 20.1187 106.5345 27.1512
LGXSM4 f 93.3143 20.1187 133.006 53.6226
LGXSM4 m 105.8333 21.7307 148.7052 62.9614
LGXSM46 f 147.425 18.8194 184.5532 110.2968
LGXSM46 m 127.72 16.8326 160.9284 94.5116
LGXSM5 f 114.575 18.8194 151.7032 77.4468
LGXSM5 m 108.2 17.7431 143.2048 73.1952


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
LGXSM10 both 113.1294 12.2286 137.2548 89.0041
LGXSM15 both 84.1343 11.9624 107.7346 60.5341
LGXSM18 both 80.769 13.4125 107.2302 54.3079
LGXSM19 both 58.0931 13.3073 84.3467 31.8396
LGXSM20 both 150.3817 16.1159 182.1763 118.587
LGXSM22 both 76.0624 10.6544 97.0821 55.0427
LGXSM23 both 74.2615 12.6244 99.1678 49.3552
LGXSM33 both 75.1067 11.3957 97.5889 52.6244
LGXSM38 both 94.0786 14.2261 122.1448 66.0123
LGXSM4 both 99.5738 14.807 128.7861 70.3615
LGXSM46 both 137.5725 12.6244 162.4788 112.6662
LGXSM5 both 111.3875 12.9324 136.9014 85.8736




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA