Project measure / variable:   Cheverud1   insulin_hifat

ID, description, units MPD:17890   insulin_hifat   insulin (serum)   [ng/mL]  high-fat diet  
high-fat diet study
Data set, strains Cheverud1   LGXSM w/par   17 strains     sex: both     age: 20-30wks
Procedure hormone quantification
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  STRAIN COMPARISON PLOT
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Cheverud1 - insulin (serum) high-fat diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested13 strains17 strains
Mean of the strain means3.67   ng/mL 7.46   ng/mL
Median of the strain means2.79   ng/mL 6.09   ng/mL
SD of the strain means± 3.37 ± 4.44
Coefficient of variation (CV)0.918 0.595
Min–max range of strain means1.20   –   14.1   ng/mL 1.21   –   18.4   ng/mL
Mean sample size per strain8.1   mice 7.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 425.7088 425.7088 23.7134 < 0.0001
strain 12 2557.7858 213.1488 11.8731 < 0.0001
sex:strain 12 376.691 31.3909 1.7486 0.0595
Residuals 191 3428.8746 17.9522


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
LGXSM10 f 4.68 2.12   9 0.705 0.452 2.02, 8.02 0.3
LGXSM10 m 3.42 1.06   9 0.352 0.308 1.46, 4.56 -0.91
LGXSM15 f 1.95 1.15   9 0.383 0.59 0.4, 3.58 -0.51
LGXSM15 m 5.87 7.17   11 2.16 1.22 0.64, 20.0 -0.36
LGXSM18 f 1.43 0.667   9 0.222 0.467 0.54, 2.56 -0.66
LGXSM18 m 6.48 3.71   8 1.31 0.573 2.04, 14.0 -0.22
LGXSM19 f 4.2 3.05   9 1.02 0.727 1.02, 11.6 0.16
LGXSM19 m 6.96 2.68   8 0.946 0.385 2.22, 11.6 -0.11
LGXSM20 f 4.53 2.85   5 1.28 0.629 1.76, 9.26 0.25
LGXSM20 m 9.94 9.27   6 3.78 0.932 0.72, 20.0 0.56
LGXSM22 f 14.1 6.05   13 1.68 0.429 2.88, 20.0 3.09
LGXSM22 m 14.6 6.05   12 1.75 0.416 3.26, 20.0 1.61
LGXSM23 f 3.03 1.65   8 0.582 0.543 1.04, 6.1 -0.19
LGXSM23 m 6.92 5.16   10 1.63 0.746 3.06, 18.7 -0.12
LGXSM31 m 5.6 3.19   4 1.6 0.57 2.9, 10.2 -0.42
LGXSM33 f 2.45 1.89   10 0.597 0.772 0.96, 7.02 -0.36
LGXSM33 m 9.89 5.53   13 1.53 0.559 2.44, 20.0 0.55
LGXSM38 f 1.2 0.555   7 0.21 0.462 0.44, 2.08 -0.73
LGXSM38 m 1.21 0.754   7 0.285 0.625 0.2, 2.18 -1.41
LGXSM39 m 3.46 3.45   3 1.99 0.997 0.98, 7.4 -0.9
LGXSM4 f 2.79 3.39   7 1.28 1.22 0.4, 10.3 -0.26
LGXSM4 m 5.85 2.5   6 1.02 0.428 1.56, 8.16 -0.36
LGXSM45 f 1.59 0.902   3 0.521 0.566 0.86, 2.6 -0.62
LGXSM45 m 5.73 4.03   3 2.33 0.704 1.16, 8.78 -0.39
LGXSM46 f 1.61 1.32   8 0.467 0.822 0.64, 4.66 -0.61
LGXSM46 m 6.09 6.88   10 2.18 1.13 0.74, 20.0 -0.31
LGXSM48 m 12.9 7.03   8 2.48 0.543 5.06, 20.0 1.23
LGXSM5 f 4.16 2.96   8 1.05 0.711 1.36, 10.2 0.15
LGXSM5 m 3.43 2.07   9 0.691 0.604 1.0, 7.26 -0.91
SM/J m 18.4 3.88   6 1.58 0.211 10.5, 20.0 2.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
LGXSM10 f 4.6756 1.4123 7.4613 1.8898
LGXSM10 m 3.4244 1.4123 6.2102 0.6387
LGXSM15 f 1.9467 1.4123 4.7324 0.0
LGXSM15 m 5.8655 1.2775 8.3853 3.3456
LGXSM18 f 1.4289 1.4123 4.2147 0.0
LGXSM18 m 6.4775 1.498 9.4323 3.5227
LGXSM19 f 4.2 1.4123 6.9858 1.4142
LGXSM19 m 6.9575 1.498 9.9123 4.0027
LGXSM20 f 4.532 1.8948 8.2695 0.7945
LGXSM20 m 9.94 1.7298 13.3519 6.5281
LGXSM22 f 14.1092 1.1751 16.4271 11.7913
LGXSM22 m 14.5567 1.2231 16.9692 12.1441
LGXSM23 f 3.0275 1.498 5.9823 0.0727
LGXSM23 m 6.922 1.3399 9.5648 4.2792
LGXSM33 f 2.448 1.3399 5.0908 0.0
LGXSM33 m 9.8908 1.1751 12.2087 7.5729
LGXSM38 f 1.2029 1.6014 4.3616 0.0
LGXSM38 m 1.2057 1.6014 4.3645 0.0
LGXSM4 f 2.7914 1.6014 5.9502 0.0
LGXSM4 m 5.8467 1.7298 9.2585 2.4348
LGXSM45 f 1.5933 2.4462 6.4184 0.0
LGXSM45 m 5.7267 2.4462 10.5518 0.9016
LGXSM46 f 1.605 1.498 4.5598 0.0
LGXSM46 m 6.088 1.3399 8.7308 3.4452
LGXSM5 f 4.16 1.498 7.1148 1.2052
LGXSM5 m 3.4311 1.4123 6.2169 0.6453


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
LGXSM10 both 4.05 0.9987 6.0198 2.0802
LGXSM15 both 3.9061 0.9522 5.7842 2.0279
LGXSM18 both 3.9532 1.0294 5.9837 1.9227
LGXSM19 both 5.5787 1.0294 7.6092 3.5483
LGXSM20 both 7.236 1.2828 9.7663 4.7057
LGXSM22 both 14.3329 0.8481 16.0058 12.6601
LGXSM23 both 4.9748 1.0049 6.9569 2.9926
LGXSM33 both 6.1694 0.8911 7.927 4.4117
LGXSM38 both 1.2043 1.1324 3.4379 0.0
LGXSM4 both 4.319 1.1786 6.6438 1.9943
LGXSM45 both 3.66 1.7298 7.0719 0.2481
LGXSM46 both 3.8465 1.0049 5.8286 1.8644
LGXSM5 both 3.7956 1.0294 5.826 1.7651




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA