Project measure / variable:   Cheverud1   spleenwt_adj_hifat

ID, description, units MPD:17872   spleenwt_adj_hifat   spleen weight as percentage of body weight   [%]  high-fat diet  
high-fat diet study
Data set, strains Cheverud1   LGXSM w/par   17 strains     sex: both     age: 20-30wks
Procedure organ weights
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  STRAIN COMPARISON PLOT
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Cheverud1 - spleen weight as percentage of body weight high-fat diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested16 strains17 strains
Mean of the strain means0.406   % 0.396   %
Median of the strain means0.385   % 0.330   %
SD of the strain means± 0.110 ± 0.142
Coefficient of variation (CV)0.271 0.358
Min–max range of strain means0.242   –   0.647   % 0.202   –   0.647   %
Mean sample size per strain7.9   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0082 0.0082 0.3522 0.5535
strain 15 3.5562 0.2371 10.2091 < 0.0001
sex:strain 15 0.5909 0.0394 1.6963 0.0528
Residuals 225 5.225 0.0232


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
LGXSM10 f 0.647 0.286   9 0.0953 0.442 0.33, 1.11 2.19
LGXSM10 m 0.647 0.276   10 0.0873 0.427 0.33, 1.19 1.77
LGXSM15 f 0.428 0.0854   9 0.0285 0.2 0.3, 0.51 0.2
LGXSM15 m 0.327 0.0775   11 0.0234 0.237 0.23, 0.48 -0.49
LGXSM18 f 0.334 0.0393   8 0.0139 0.118 0.26, 0.39 -0.65
LGXSM18 m 0.301 0.0916   8 0.0324 0.304 0.16, 0.44 -0.67
LGXSM19 f 0.431 0.134   9 0.0445 0.31 0.21, 0.61 0.23
LGXSM19 m 0.339 0.0318   8 0.0113 0.0939 0.29, 0.38 -0.4
LGXSM20 f 0.519 0.0979   8 0.0346 0.189 0.4, 0.69 1.02
LGXSM20 m 0.59 0.251   6 0.103 0.426 0.4, 1.08 1.36
LGXSM22 f 0.337 0.111   13 0.0307 0.329 0.21, 0.66 -0.63
LGXSM22 m 0.304 0.0998   12 0.0288 0.328 0.19, 0.58 -0.65
LGXSM23 f 0.574 0.359   8 0.127 0.625 0.29, 1.41 1.52
LGXSM23 m 0.516 0.118   8 0.0417 0.229 0.33, 0.68 0.84
LGXSM31 f 0.356 0.0871   5 0.0389 0.245 0.27, 0.45 -0.45
LGXSM31 m 0.33 0.0395   6 0.0161 0.12 0.28, 0.37 -0.47
LGXSM33 f 0.504 0.0863   8 0.0305 0.171 0.38, 0.65 0.89
LGXSM33 m 0.63 0.129   7 0.0487 0.205 0.42, 0.78 1.65
LGXSM35 f 0.336 0.0721   7 0.0272 0.215 0.25, 0.42 -0.64
LGXSM35 m 0.255 0.0576   8 0.0204 0.226 0.2, 0.37 -1.0
LGXSM39 f 0.3 0.0796   8 0.0282 0.265 0.22, 0.47 -0.96
LGXSM39 m 0.572 0.361   9 0.12 0.63 0.21, 1.27 1.24
LGXSM4 f 0.326 0.115   8 0.0405 0.351 0.21, 0.52 -0.73
LGXSM4 m 0.325 0.0909   6 0.0371 0.28 0.2, 0.43 -0.5
LGXSM45 f 0.44 0.104   5 0.0465 0.236 0.31, 0.55 0.31
LGXSM45 m 0.473 0.193   3 0.111 0.408 0.32, 0.69 0.54
LGXSM46 f 0.242 0.0876   9 0.0292 0.362 0.14, 0.41 -1.49
LGXSM46 m 0.202 0.0601   10 0.019 0.298 0.13, 0.33 -1.37
LGXSM48 f 0.309 0.0641   7 0.0242 0.208 0.23, 0.42 -0.88
LGXSM48 m 0.333 0.13   8 0.046 0.391 0.23, 0.56 -0.45
LGXSM5 f 0.414 0.037   8 0.0131 0.0894 0.36, 0.48 0.07
LGXSM5 m 0.296 0.109   8 0.0387 0.369 0.19, 0.55 -0.71
SM/J m 0.3 0.0629   6 0.0257 0.21 0.24, 0.39 -0.68


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
LGXSM10 f 0.6467 0.0508 0.7468 0.5466
LGXSM10 m 0.647 0.0482 0.742 0.552
LGXSM15 f 0.4278 0.0508 0.5279 0.3277
LGXSM15 m 0.3273 0.0459 0.4178 0.2367
LGXSM18 f 0.3337 0.0539 0.4399 0.2276
LGXSM18 m 0.3012 0.0539 0.4074 0.1951
LGXSM19 f 0.4311 0.0508 0.5312 0.331
LGXSM19 m 0.3388 0.0539 0.4449 0.2326
LGXSM20 f 0.5188 0.0539 0.6249 0.4126
LGXSM20 m 0.59 0.0622 0.7126 0.4674
LGXSM22 f 0.3369 0.0423 0.4202 0.2536
LGXSM22 m 0.3042 0.044 0.3909 0.2175
LGXSM23 f 0.5737 0.0539 0.6799 0.4676
LGXSM23 m 0.5162 0.0539 0.6224 0.4101
LGXSM31 f 0.356 0.0682 0.4903 0.2217
LGXSM31 m 0.33 0.0622 0.4526 0.2074
LGXSM33 f 0.5038 0.0539 0.6099 0.3976
LGXSM33 m 0.63 0.0576 0.7435 0.5165
LGXSM35 f 0.3357 0.0576 0.4492 0.2222
LGXSM35 m 0.255 0.0539 0.3612 0.1488
LGXSM39 f 0.3 0.0539 0.4062 0.1938
LGXSM39 m 0.5722 0.0508 0.6723 0.4721
LGXSM4 f 0.3263 0.0539 0.4324 0.2201
LGXSM4 m 0.325 0.0622 0.4476 0.2024
LGXSM45 f 0.44 0.0682 0.5743 0.3057
LGXSM45 m 0.4733 0.088 0.6467 0.3
LGXSM46 f 0.2422 0.0508 0.3423 0.1421
LGXSM46 m 0.202 0.0482 0.297 0.107
LGXSM48 f 0.3086 0.0576 0.4221 0.1951
LGXSM48 m 0.3325 0.0539 0.4387 0.2263
LGXSM5 f 0.4137 0.0539 0.5199 0.3076
LGXSM5 m 0.2962 0.0539 0.4024 0.1901


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
LGXSM10 both 0.6468 0.035 0.7158 0.5778
LGXSM15 both 0.3775 0.0342 0.445 0.31
LGXSM18 both 0.3175 0.0381 0.3926 0.2424
LGXSM19 both 0.3849 0.037 0.4579 0.312
LGXSM20 both 0.5544 0.0411 0.6355 0.4733
LGXSM22 both 0.3205 0.0305 0.3807 0.2604
LGXSM23 both 0.545 0.0381 0.6201 0.4699
LGXSM31 both 0.343 0.0461 0.4339 0.2521
LGXSM33 both 0.5669 0.0394 0.6446 0.4892
LGXSM35 both 0.2954 0.0394 0.3731 0.2176
LGXSM39 both 0.4361 0.037 0.5091 0.3632
LGXSM4 both 0.3256 0.0411 0.4067 0.2445
LGXSM45 both 0.4567 0.0556 0.5663 0.347
LGXSM46 both 0.2221 0.035 0.2911 0.1531
LGXSM48 both 0.3205 0.0394 0.3982 0.2428
LGXSM5 both 0.355 0.0381 0.4301 0.2799




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA