Project measure / variable:   Cheverud1   insulin_ctrl

ID, description, units MPD:17840   insulin_ctrl   insulin (serum)   [ng/mL]  control diet  
high-fat diet study
Data set, strains Cheverud1   LGXSM w/par   15 strains     sex: both     age: 20-30wks
Procedure hormone quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Cheverud1 - insulin (serum) control diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains15 strains
Mean of the strain means1.92   ng/mL 4.71   ng/mL
Median of the strain means1.15   ng/mL 4.20   ng/mL
SD of the strain means± 2.17 ± 2.74
Coefficient of variation (CV)1.13 0.582
Min–max range of strain means0.617   –   9.07   ng/mL 1.02   –   10.7   ng/mL
Mean sample size per strain7.8   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 458.6013 458.6013 26.9237 < 0.0001
strain 13 962.9451 74.0727 4.3487 < 0.0001
sex:strain 13 725.1143 55.778 3.2746 0.0002
Residuals 198 3372.6092 17.0334


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
LGXSM10 f 2.75 1.22   7 0.463 0.446 0.56, 4.04 0.38
LGXSM10 m 1.83 0.543   8 0.192 0.296 0.58, 2.44 -1.05
LGXSM15 f 1.16 0.902   9 0.301 0.775 0.2, 3.12 -0.35
LGXSM15 m 2.49 2.61   11 0.786 1.05 0.2, 9.22 -0.81
LGXSM18 f 0.811 0.287   9 0.0956 0.353 0.26, 1.16 -0.51
LGXSM18 m 4.2 3.99   8 1.41 0.951 0.7, 13.7 -0.19
LGXSM19 f 1.34 1.31   8 0.464 0.982 0.2, 4.18 -0.27
LGXSM19 m 7.44 5.57   9 1.86 0.749 2.22, 20.0 0.99
LGXSM20 f 1.13 0.921   6 0.376 0.815 0.2, 2.32 -0.36
LGXSM20 m 7.08 8.84   7 3.34 1.25 1.34, 20.0 0.86
LGXSM22 f 9.07 6.04   12 1.74 0.666 1.14, 20.0 3.29
LGXSM22 m 4.95 4.28   8 1.51 0.865 0.7, 13.1 0.09
LGXSM23 f 2.38 3.32   10 1.05 1.4 0.2, 11.4 0.21
LGXSM23 m 8.88 8.21   13 2.28 0.925 0.46, 20.0 1.52
LGXSM31 m 3.11 2.85   4 1.43 0.916 0.76, 6.92 -0.58
LGXSM33 f 1.38 1.01   9 0.337 0.734 0.32, 3.66 -0.25
LGXSM33 m 10.7 6.84   11 2.06 0.637 1.52, 20.0 2.18
LGXSM38 f 1.02 0.606   8 0.214 0.596 0.2, 1.96 -0.41
LGXSM38 m 1.02 0.63   8 0.223 0.618 0.36, 2.12 -1.35
LGXSM4 f 0.829 0.419   7 0.158 0.506 0.32, 1.44 -0.5
LGXSM4 m 2.54 1.62   8 0.573 0.639 0.3, 5.04 -0.79
LGXSM45 f 0.81 0.385   4 0.193 0.476 0.4, 1.3 -0.51
LGXSM45 m 5.25 3.74   3 2.16 0.714 2.3, 9.46 0.2
LGXSM46 f 0.977 0.434   7 0.164 0.444 0.32, 1.36 -0.43
LGXSM46 m 3.5 4.16   9 1.39 1.19 0.26, 13.2 -0.44
LGXSM48 f 0.617 0.411   6 0.168 0.667 0.32, 1.4 -0.6
LGXSM48 m 4.63 6.84   7 2.58 1.48 0.46, 20.0 -0.03
LGXSM5 f 2.56 2.57   8 0.91 1.01 0.62, 8.6 0.3
LGXSM5 m 3.06 1.16   6 0.475 0.38 1.86, 4.66 -0.6


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
LGXSM10 f 2.7457 1.5599 5.8219 0.0
LGXSM10 m 1.835 1.4592 4.7125 0.0
LGXSM15 f 1.1644 1.3757 3.8774 0.0
LGXSM15 m 2.4891 1.2444 4.943 0.0351
LGXSM18 f 0.8111 1.3757 3.524 0.0
LGXSM18 m 4.1975 1.4592 7.075 1.32
LGXSM19 f 1.335 1.4592 4.2125 0.0
LGXSM19 m 7.4422 1.3757 10.1552 4.7293
LGXSM20 f 1.13 1.6849 4.4527 0.0
LGXSM20 m 7.08 1.5599 10.1562 4.0038
LGXSM22 f 9.0717 1.1914 11.4211 6.7222
LGXSM22 m 4.945 1.4592 7.8225 2.0675
LGXSM23 f 2.376 1.3051 4.9497 0.0
LGXSM23 m 8.8815 1.1447 11.1388 6.6242
LGXSM33 f 1.38 1.3757 4.0929 0.0
LGXSM33 m 10.7382 1.2444 13.1921 8.2842
LGXSM38 f 1.0175 1.4592 3.895 0.0
LGXSM38 m 1.02 1.4592 3.8975 0.0
LGXSM4 f 0.8286 1.5599 3.9048 0.0
LGXSM4 m 2.5363 1.4592 5.4138 0.0
LGXSM45 f 0.81 2.0636 4.8794 0.0
LGXSM45 m 5.2467 2.3828 9.9456 0.5477
LGXSM46 f 0.9771 1.5599 4.0533 0.0
LGXSM46 m 3.4978 1.3757 6.2107 0.7848
LGXSM48 f 0.6167 1.6849 3.9393 0.0
LGXSM48 m 4.6314 1.5599 7.7076 1.5552
LGXSM5 f 2.555 1.4592 5.4325 0.0
LGXSM5 m 3.06 1.6849 6.3827 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
LGXSM10 both 2.2904 1.068 4.3965 0.1842
LGXSM15 both 1.8268 0.9275 3.6558 0.0
LGXSM18 both 2.5043 1.0027 4.4817 0.5269
LGXSM19 both 4.3886 1.0027 6.366 2.4112
LGXSM20 both 4.105 1.1481 6.369 1.841
LGXSM22 both 7.0083 0.9419 8.8658 5.1509
LGXSM23 both 5.6288 0.868 7.3405 3.9171
LGXSM33 both 6.0591 0.9275 7.8882 4.23
LGXSM38 both 1.0188 1.0318 3.0535 0.0
LGXSM4 both 1.6824 1.068 3.7885 0.0
LGXSM45 both 3.0283 1.5761 6.1364 0.0
LGXSM46 both 2.2375 1.0399 4.2882 0.1867
LGXSM48 both 2.624 1.1481 4.8881 0.36
LGXSM5 both 2.8075 1.1145 5.0052 0.6098




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA