Project measure / variable:   Wahlsten2   rrod

ID, description, units MPD:16009   rrod   wildness rating, mean during rotarod   [score]  
Data set, strains Wahlsten2   inbred   21 strains     sex: both     age: 10-12wks
Procedure behavior observation
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  STRAIN COMPARISON PLOT
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Wahlsten2 - wildness rating, mean during rotarod



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains20 strains
Mean of the strain means1.24   score 0.732   score
Median of the strain means0.900   score 0.575   score
SD of the strain means± 1.43 ± 0.601
Coefficient of variation (CV)1.16 0.821
Min–max range of strain means0.0833   –   6.32   score 0   –   2.15   score
Mean sample size per strain8.6   mice 8.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3.3243 3.3243 4.5437 0.0338
strain 19 185.8166 9.7798 13.3672 < 0.0001
sex:strain 19 13.4879 0.7099 0.9703 0.4963
Residuals 306 223.8786 0.7316


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.45 0.256   8 0.0906 0.57 0.2, 0.8 -0.55
129S1/SvImJ m 0.311 0.226   9 0.0754 0.727 -0.7
A/J f 0.325 0.399   8 0.141 1.23 -0.64
A/J m 0.125 0.104   8 0.0366 0.828 -1.01
AKR/J f 0.914 0.279   7 0.106 0.306 0.6, 1.4 -0.22
AKR/J m 0.825 0.362   8 0.128 0.438 0.4, 1.4 0.15
BALB/cByJ f 0.48 0.402   10 0.127 0.838 -0.53
BALB/cByJ m 0.15 0.207   8 0.0732 1.38 -0.97
BTBR T+ Itpr3tf/J f 1.07 0.837   12 0.242 0.785 0.2, 2.8 -0.12
BTBR T+ Itpr3tf/J m 1.2 0.632   4 0.316 0.527 0.4, 1.8 0.78
C3H/HeJ f 0.775 0.271   8 0.0959 0.35 0.4, 1.2 -0.32
C3H/HeJ m 0.5 0.414   8 0.146 0.828 0.2, 1.4 -0.39
C57BL/6J f 0.6 0.4   8 0.141 0.667 0.2, 1.4 -0.44
C57BL/6J m 0.55 0.382   8 0.135 0.694 -0.3
C57L/J f 0.48 0.193   10 0.0611 0.403 0.2, 0.8 -0.53
C57L/J m 0.433 0.32   6 0.131 0.739 0.2, 1.0 -0.5
C58/J f 1.11 1.02   7 0.385 0.914 -0.09
C58/J m 0.6 0.618   10 0.196 1.03 -0.22
CAST/EiJ f 1.65 1.42   8 0.501 0.859 0.2, 4.8 0.29
CAST/EiJ m 1.45 0.762   8 0.269 0.525 0.8, 3.0 1.19
DBA/2J f 0.95 0.715   8 0.253 0.753 0.2, 2.2 -0.2
DBA/2J m 0.65 0.298   8 0.105 0.458 0.2, 1.0 -0.14
FVB/NJ f 0.9 0.773   10 0.244 0.859 -0.23
FVB/NJ m 0.7 0.545   8 0.193 0.779 0.2, 1.8 -0.05
MOLF/EiJ f 1.32 1.82   8 0.645 1.38 0.06
MOLF/EiJ m 1.17 0.742   6 0.303 0.636 0.4, 2.2 0.73
NOD/ShiLtJ f 1.65 1.53   8 0.54 0.925 0.2, 4.0 0.29
NOD/ShiLtJ m 1.05 1.17   12 0.339 1.12 0.53
NZB/BlNJ f 0.4 0.456   6 0.186 1.14 -0.58
NZB/BlNJ m 0.345 0.439   11 0.132 1.27 -0.64
PERA/EiJ f 3.8 1.94   10 0.614 0.511 0.4, 7.0 1.79
PERA/EiJ m 2.15 1.77   12 0.512 0.825 2.36
PL/J f 0.0833 0.159   12 0.0458 1.9 -0.8
PL/J m 0.0 0.0   6 0.0 0.0 -1.22
SJL/J f 0.25 0.177   8 0.0627 0.709 -0.69
SJL/J m 0.4 0.298   10 0.0943 0.745 -0.55
SM/J f 0.257 0.38   14 0.101 1.48 -0.68
SM/J m 0.075 0.104   8 0.0366 1.38 -1.09
SPRET/EiJ f 6.32 1.06   5 0.476 0.168 5.0, 7.6 3.54
SWR/J f 2.18 1.09   8 0.384 0.5 0.8, 3.6 0.66
SWR/J m 1.96 1.67   10 0.528 0.852 0.6, 5.0 2.04


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.45 0.3024 1.0451 -0.1451
129S1/SvImJ m 0.3111 0.2851 0.8722 -0.2499
A/J f 0.325 0.3024 0.9201 -0.2701
A/J m 0.125 0.3024 0.7201 -0.4701
AKR/J f 0.9143 0.3233 1.5504 0.2781
AKR/J m 0.825 0.3024 1.4201 0.2299
BALB/cByJ f 0.48 0.2705 1.0122 -0.0522
BALB/cByJ m 0.15 0.3024 0.7451 -0.4451
BTBR T+ Itpr3tf/J f 1.0667 0.2469 1.5525 0.5808
BTBR T+ Itpr3tf/J m 1.2 0.4277 2.0416 0.3584
C3H/HeJ f 0.775 0.3024 1.3701 0.1799
C3H/HeJ m 0.5 0.3024 1.0951 -0.0951
C57BL/6J f 0.6 0.3024 1.1951 0.0049
C57BL/6J m 0.55 0.3024 1.1451 -0.0451
C57L/J f 0.48 0.2705 1.0122 -0.0522
C57L/J m 0.4333 0.3492 1.1205 -0.2538
C58/J f 1.1143 0.3233 1.7504 0.4781
C58/J m 0.6 0.2705 1.1322 0.0678
CAST/EiJ f 1.65 0.3024 2.2451 1.0549
CAST/EiJ m 1.45 0.3024 2.0451 0.8549
DBA/2J f 0.95 0.3024 1.5451 0.3549
DBA/2J m 0.65 0.3024 1.2451 0.0549
FVB/NJ f 0.9 0.2705 1.4322 0.3678
FVB/NJ m 0.7 0.3024 1.2951 0.1049
MOLF/EiJ f 1.325 0.3024 1.9201 0.7299
MOLF/EiJ m 1.1667 0.3492 1.8538 0.4795
NOD/ShiLtJ f 1.65 0.3024 2.2451 1.0549
NOD/ShiLtJ m 1.05 0.2469 1.5359 0.5641
NZB/BlNJ f 0.4 0.3492 1.0871 -0.2871
NZB/BlNJ m 0.3455 0.2579 0.8529 -0.162
PERA/EiJ f 3.8 0.2705 4.3322 3.2678
PERA/EiJ m 2.15 0.2469 2.6359 1.6641
PL/J f 0.0833 0.2469 0.5692 -0.4025
PL/J m 0.0 0.3492 0.6871 -0.6871
SJL/J f 0.25 0.3024 0.8451 -0.3451
SJL/J m 0.4 0.2705 0.9322 -0.1322
SM/J f 0.2571 0.2286 0.707 -0.1927
SM/J m 0.075 0.3024 0.6701 -0.5201
SWR/J f 2.175 0.3024 2.7701 1.5799
SWR/J m 1.96 0.2705 2.4922 1.4278


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.3806 0.2078 0.7895 -0.0284
A/J both 0.225 0.2138 0.6458 -0.1958
AKR/J both 0.8696 0.2213 1.3052 0.4341
BALB/cByJ both 0.315 0.2029 0.7142 -0.0842
BTBR T+ Itpr3tf/J both 1.1333 0.2469 1.6192 0.6475
C3H/HeJ both 0.6375 0.2138 1.0583 0.2167
C57BL/6J both 0.575 0.2138 0.9958 0.1542
C57L/J both 0.4567 0.2209 0.8912 0.0221
C58/J both 0.8571 0.2108 1.2719 0.4424
CAST/EiJ both 1.55 0.2138 1.9708 1.1292
DBA/2J both 0.8 0.2138 1.2208 0.3792
FVB/NJ both 0.8 0.2029 1.1992 0.4008
MOLF/EiJ both 1.2458 0.231 1.7003 0.7913
NOD/ShiLtJ both 1.35 0.1952 1.7341 0.9659
NZB/BlNJ both 0.3727 0.2171 0.7998 -0.0544
PERA/EiJ both 2.975 0.1831 3.3353 2.6147
PL/J both 0.0417 0.2138 0.4624 -0.3791
SJL/J both 0.325 0.2029 0.7242 -0.0742
SM/J both 0.1661 0.1895 0.5391 -0.2069
SWR/J both 2.0675 0.2029 2.4667 1.6683




  GWAS USING LINEAR MIXED MODELS