Project measure / variable:   Crabbe1   bal19_doseC

ID, description, units MPD:15416   bal19_doseC   missteps crossing 19.0 mm wide balance beam   [n]  dose 1.4 g/kg i.p.  
ethanol study
Data set, strains Crabbe1   inbred   8 strains     sex: both     age: 8-16wks
Procedure balance beam
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  STRAIN COMPARISON PLOT
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Crabbe1 - missteps crossing 19.0 mm wide balance beam dose 1.4 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means2.59   n 2.00   n
Median of the strain means2.01   n 1.69   n
SD of the strain means± 2.39 ± 1.19
Coefficient of variation (CV)0.922 0.595
Min–max range of strain means0.668   –   8.18   n 0.170   –   3.87   n
Mean sample size per strain4.4   mice 4.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.4297 1.4297 0.3243 0.5716
strain 6 73.6073 12.2679 2.783 0.0208
sex:strain 6 52.4975 8.7496 1.9849 0.0859
Residuals 49 215.9983 4.4081


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 8.18 6.39   2   4.52 0.78 3.67, 12.7 2.34
129S1/SvImJ m 2.92 1.71   4 0.854 0.585 0.67, 4.67 0.77
A/J f 2.67 2.08   4 1.04 0.78 0.17, 5.17 0.03
A/J m 0.17 0.0   1   0.0 0.0 0.17, 0.17 -1.54
BALB/cByJ f 1.94 1.69   5 0.756 0.873 -0.27
BALB/cByJ m 1.67 2.66   6 1.09 1.59 -0.28
BTBR T+ Itpr3tf/J f 2.73 3.29   5 1.47 1.2 0.33, 8.33 0.06
BTBR T+ Itpr3tf/J m 3.06 2.38   5 1.07 0.778 0.89
C3H/HeJ f 2.08 1.26   4 0.629 0.605 0.83, 3.83 -0.21
C3H/HeJ m 1.22 1.45   3 0.84 1.19 -0.66
C57BL/6J f 1.75 1.71   4 0.854 0.975 -0.35
C57BL/6J m 3.87 1.3   5 0.583 0.337 2.67, 5.67 1.56
DBA/2J f 0.668 0.818   6 0.334 1.22 -0.8
DBA/2J m 1.42 0.957   4 0.479 0.674 0.67, 2.67 -0.49
FVB/NJ f 0.7 1.04   5 0.464 1.48 -0.79
FVB/NJ m 1.7 2.17   5 0.97 1.28 0.5, 5.5 -0.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 8.185 1.4846 11.1684 5.2016
129S1/SvImJ m 2.92 1.0498 5.0296 0.8104
BALB/cByJ f 1.936 0.9389 3.8229 0.0491
BALB/cByJ m 1.6683 0.8571 3.3908 0.0
BTBR T+ Itpr3tf/J f 2.73 0.9389 4.6169 0.8431
BTBR T+ Itpr3tf/J m 3.064 0.9389 4.9509 1.1771
C3H/HeJ f 2.08 1.0498 4.1896 0.0
C3H/HeJ m 1.22 1.2122 3.656 0.0
C57BL/6J f 1.7525 1.0498 3.8621 0.0
C57BL/6J m 3.87 0.9389 5.7569 1.9831
DBA/2J f 0.6683 0.8571 2.3908 0.0
DBA/2J m 1.42 1.0498 3.5296 0.0
FVB/NJ f 0.7 0.9389 2.5869 0.0
FVB/NJ m 1.7 0.9389 3.5869 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 5.5525 0.9091 7.3795 3.7255
BALB/cByJ both 1.8022 0.6357 3.0796 0.5247
BTBR T+ Itpr3tf/J both 2.897 0.6639 4.2312 1.5628
C3H/HeJ both 1.65 0.8018 3.2612 0.0388
C57BL/6J both 2.8113 0.7042 4.2264 1.3961
DBA/2J both 1.0442 0.6776 2.4059 0.0
FVB/NJ both 1.2 0.6639 2.5342 0.0




  GWAS USING LINEAR MIXED MODELS