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Project measure / variable:   Crabbe1   bal15_doseC

ID, description, units MPD:15413   bal15_doseC   missteps crossing 15.8mm wide balance beam   [n]  dose 1.4 g/kg i.p.  
ethanol study
Data set, strains Crabbe1   inbred   8 strains     sex: both     age: 8-16wks
Procedure balance beam
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  STRAIN COMPARISON PLOT
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Crabbe1 - missteps crossing 15.8mm wide balance beam dose 1.4 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means3.72   n 3.15   n
Median of the strain means3.84   n 3.11   n
SD of the strain means± 2.06 ± 1.57
Coefficient of variation (CV)0.554 0.499
Min–max range of strain means0.499   –   7.07   n 0   –   5.50   n
Mean sample size per strain5.9   mice 4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.3577 0.3577 0.0513 0.8215
strain 6 109.667 18.2778 2.6224 0.0246
sex:strain 6 57.6532 9.6089 1.3786 0.2368
Residuals 64 446.0799 6.97


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 7.07 4.26   4 2.13 0.602 1.83, 11.8 1.62
129S1/SvImJ m 3.83 0.0   2   0.0 0.0 3.83, 3.83 0.43
A/J f 4.83 3.06   3 1.76 0.632 1.5, 7.5 0.54
A/J m 0.0 0.0   1   0.0 0.0 -2.0
BALB/cByJ f 2.02 2.06   7 0.778 1.02 -0.83
BALB/cByJ m 4.19 4.46   6 1.82 1.06 0.66
BTBR T+ Itpr3tf/J f 2.43 1.55   7 0.585 0.638 -0.63
BTBR T+ Itpr3tf/J m 2.73 1.52   5 0.678 0.556 1.33, 4.33 -0.27
C3H/HeJ f 5.25 4.79   4 2.39 0.912 1.5, 11.5 0.74
C3H/HeJ m 5.5 2.83   2   2.0 0.514 3.5, 7.5 1.49
C57BL/6J f 4.0 3.11   7 1.18 0.778 0.13
C57BL/6J m 2.74 2.07   7 0.782 0.755 0.17, 6.17 -0.26
DBA/2J f 3.69 2.53   8 0.896 0.687 -0.02
DBA/2J m 3.1 2.07   5 0.927 0.669 0.5, 5.5 -0.03
FVB/NJ f 0.499 0.706   7 0.267 1.42 -1.56
FVB/NJ m 3.12 1.7   7 0.644 0.547 0.83, 5.83 -0.02


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 7.0725 1.32 9.7096 4.4354
129S1/SvImJ m 3.83 1.8668 7.5594 0.1006
BALB/cByJ f 2.0214 0.9979 4.0149 0.028
BALB/cByJ m 4.1867 1.0778 6.3398 2.0335
BTBR T+ Itpr3tf/J f 2.4257 0.9979 4.4192 0.4323
BTBR T+ Itpr3tf/J m 2.73 1.1807 5.0887 0.3713
C3H/HeJ f 5.25 1.32 7.8871 2.6129
C3H/HeJ m 5.5 1.8668 9.2294 1.7706
C57BL/6J f 4.0029 0.9979 5.9963 2.0094
C57BL/6J m 2.7414 0.9979 4.7349 0.748
DBA/2J f 3.6875 0.9334 5.5522 1.8228
DBA/2J m 3.1 1.1807 5.4587 0.7413
FVB/NJ f 0.4986 0.9979 2.492 0.0
FVB/NJ m 3.1157 0.9979 5.1092 1.1223


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 5.4513 1.1432 7.735 3.1675
BALB/cByJ both 3.104 0.7344 4.5712 1.6369
BTBR T+ Itpr3tf/J both 2.5779 0.7729 4.122 1.0337
C3H/HeJ both 5.375 1.1432 7.6588 3.0912
C57BL/6J both 3.3721 0.7056 4.7817 1.9626
DBA/2J both 3.3937 0.7525 4.8971 1.8904
FVB/NJ both 1.8071 0.7056 3.2167 0.3976




  GWAS USING LINEAR MIXED MODELS