Project measure / variable:   Johnson1   pip16kHz_old

ID, description, units MPD:1409   pip16kHz_old   auditory brainstem response (ABR) threshold, 15-72 wk old group, sound pressure level   [dB]  16kHz pip stimulus  
Data set, strains Johnson1   inbred   27 strains     sex: both     age: 15-72wks
Procedure ABR test
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  STRAIN COMPARISON PLOT
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Johnson1 - auditory brainstem response (ABR) threshold, 15-72 wk old group, sound pressure level 16kHz pip stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains19 strains
Mean of the strain means40.6   dB 44.6   dB
Median of the strain means30.8   dB 39.4   dB
SD of the strain means± 26.8 ± 28.9
Coefficient of variation (CV)0.661 0.647
Min–max range of strain means11.7   –   99.0   dB 14.0   –   93.1   dB
Mean sample size per strain11.4   mice 10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 936.3087 936.3087 2.7857 0.096
strain 12 183725.5231 15310.4603 45.5517 < 0.0001
sex:strain 12 7502.6494 625.2208 1.8602 0.0383
Residuals 340 114277.9041 336.1115


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3/J f 61.0 25.2   9 8.38 0.412 25.0, 99.0 0.76
129P3/J m 74.4 13.3   9 4.44 0.179 45.0, 90.0 1.03
129T2/SvEmsJ m 16.7 4.08   6 1.67 0.245 10.0, 20.0 -0.97
129X1/SvJ m 39.4 26.0   8 9.18 0.66 15.0, 75.0 -0.18
A/HeJ f 22.4 7.1   43 1.08 0.316 15.0, 45.0 -0.68
A/HeJ m 25.0 7.64   13 2.12 0.306 15.0, 45.0 -0.68
A/J f 86.2 14.5   18 3.41 0.168 60.0, 99.0 1.7
A/J m 93.1 10.2   19 2.33 0.109 65.0, 99.0 1.68
A/WySnJ f 39.4 22.1   42 3.41 0.561 15.0, 99.0 -0.04
A/WySnJ m 34.4 18.1   24 3.7 0.528 20.0, 70.0 -0.35
BUB/BnJ m 84.0 12.0   7 4.53 0.143 70.0, 99.0 1.37
C3H/HeJ f 18.3 6.06   6 2.47 0.33 10.0, 25.0 -0.83
C57BL/6J f 43.9 36.2   17 8.79 0.826 15.0, 99.0 0.12
C57BL/6J m 57.3 36.2   23 7.56 0.632 15.0, 99.0 0.44
C57BLKS/J f 42.9 31.7   7 12.0 0.74 15.0, 80.0 0.09
C57BR/cdJ f 60.6 22.0   16 5.5 0.363 15.0, 99.0 0.75
C57BR/cdJ m 40.9 12.8   11 3.86 0.313 20.0, 60.0 -0.13
C57L/J f 56.1 17.9   22 3.83 0.32 30.0, 99.0 0.58
C57L/J m 43.9 5.46   9 1.82 0.125 35.0, 50.0 -0.02
CAST/EiJ f 11.7 4.08   6 1.67 0.35 10.0, 20.0 -1.08
CAST/EiJ m 15.6 14.9   9 4.96 0.957 10.0, 55.0 -1.0
CBA/CaJ f 15.0 2.5   17 0.606 0.167 10.0, 20.0 -0.95
CBA/CaJ m 14.5 6.43   10 2.03 0.444 10.0, 30.0 -1.04
DBA/2HaSmnJ f 24.2 15.6   6 6.38 0.647 10.0, 40.0 -0.61
DBA/2HaSmnJ m 22.5 11.7   6 4.79 0.521 15.0, 40.0 -0.76
DBA/2J m 83.6 16.0   9 5.33 0.191 55.0, 99.0 1.35
IDH2/Ei f 27.2 17.0   9 5.66 0.624 15.0, 70.0 -0.5
LP/J f 93.6 4.93   5 2.2 0.0527 90.0, 99.0 1.98
MA/MyJ m 59.9 19.1   9 6.37 0.319 30.0, 99.0 0.53
MOLD/RkJ f 17.5 5.24   6 2.14 0.3 10.0, 25.0 -0.86
NOD/ShiLtJ m 92.7 14.5   9 4.82 0.156 55.0, 99.0 1.67
NON/ShiLtJ f 15.0 3.16   6 1.29 0.211 10.0, 20.0 -0.95
NON/ShiLtJ m 14.0 2.24   5 1.0 0.16 10.0, 15.0 -1.06
P/J f 24.2 17.7   6 7.24 0.733 15.0, 60.0 -0.61
SENCARA/PtJ f 48.0 22.0   5 9.82 0.458 20.0, 70.0 0.28
SKH2/J f 99.0 0.0   5 0.0 0.0 99.0, 99.0 2.18
SWR/J f 15.0 4.08   7 1.54 0.272 10.0, 20.0 -0.95
SWR/J m 16.0 6.52   5 2.92 0.407 10.0, 25.0 -0.99
YBR/EiJ f 30.8 17.4   6 7.12 0.566 10.0, 55.0 -0.36
YBR/EiJ m 18.8 3.54   8 1.25 0.189 15.0, 25.0 -0.89


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3/J f 61.0 6.1111 73.0204 48.9796
129P3/J m 74.4444 6.1111 86.4648 62.4241
A/HeJ f 22.4419 2.7958 27.9411 16.9426
A/HeJ m 25.0 5.0848 35.0015 14.9985
A/J f 86.1667 4.3212 94.6663 77.667
A/J m 93.1053 4.206 101.3782 84.8323
A/WySnJ f 39.381 2.8289 44.9453 33.8166
A/WySnJ m 34.375 3.7423 41.7359 27.0141
C57BL/6J f 43.8824 4.4465 52.6284 35.1363
C57BL/6J m 57.3478 3.8228 64.8671 49.8286
C57BR/cdJ f 60.5625 4.5833 69.5778 51.5472
C57BR/cdJ m 40.9091 5.5277 51.7819 30.0363
C57L/J f 56.0909 3.9087 63.7792 48.4027
C57L/J m 43.8889 6.1111 55.9092 31.8685
CAST/EiJ f 11.6667 7.4846 26.3885 0.0
CAST/EiJ m 15.5556 6.1111 27.5759 3.5352
CBA/CaJ f 15.0 4.4465 23.7461 6.2539
CBA/CaJ m 14.5 5.7975 25.9035 3.0965
DBA/2HaSmnJ f 24.1667 7.4846 38.8885 9.4448
DBA/2HaSmnJ m 22.5 7.4846 37.2219 7.7781
NON/ShiLtJ f 15.0 7.4846 29.7219 0.2781
NON/ShiLtJ m 14.0 8.1989 30.127 0.0
SWR/J f 15.0 6.9294 28.6298 1.3702
SWR/J m 16.0 8.1989 32.127 0.0
YBR/EiJ f 30.8333 7.4846 45.5552 16.1115
YBR/EiJ m 18.75 6.4818 31.4995 6.0005


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3/J both 67.7222 4.3212 76.2219 59.2225
A/HeJ both 23.7209 2.9013 29.4278 18.0141
A/J both 89.636 3.0151 95.5665 83.7054
A/WySnJ both 36.878 2.3456 41.4917 32.2643
C57BL/6J both 50.6151 2.9319 56.3821 44.8481
C57BR/cdJ both 50.7358 3.5904 57.7979 43.6737
C57L/J both 49.9899 3.6271 57.1243 42.8555
CAST/EiJ both 13.6111 4.8313 23.114 4.1082
CBA/CaJ both 14.75 3.6532 21.9356 7.5644
DBA/2HaSmnJ both 23.3333 5.2924 33.7433 12.9234
NON/ShiLtJ both 14.5 5.5507 25.418 3.582
SWR/J both 15.5 5.3675 26.0576 4.9424
YBR/EiJ both 24.7917 4.9506 34.5293 15.0541




  GWAS USING LINEAR MIXED MODELS