Project measure / variable:   Flaherty1   pct_open

ID, description, units MPD:11813   pct_open   percentage of time in open quadrants   [%]  both  
Data set, strains Flaherty1   inbred   8 strains     sex: both     age: 8-9wks
Procedure elevated zero maze
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  STRAIN COMPARISON PLOT
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Flaherty1 - percentage of time in open quadrants both



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means18.0   % 16.7   %
Median of the strain means14.1   % 11.3   %
SD of the strain means± 10.4 ± 10.6
Coefficient of variation (CV)0.578 0.632
Min–max range of strain means5.43   –   32.2   % 6.27   –   34.4   %
Mean sample size per strain19.9   mice 19.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 143.9032 143.9032 1.1314 0.2883
strain 7 29899.073 4271.2961 33.5825 < 0.0001
sex:strain 7 525.4024 75.0575 0.5901 0.7639
Residuals 301 38283.6483 127.1882


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 13.1 21.7   20 4.86 1.65 -0.47
129S1/SvImJ m 9.4 7.92   20 1.77 0.842 0.267, 24.2 -0.69
A/J f 5.43 6.34   20 1.42 1.17 -1.21
A/J m 6.27 7.06   20 1.58 1.13 -0.99
BALB/cByJ f 12.8 15.9   20 3.55 1.24 -0.5
BALB/cByJ m 8.94 9.25   20 2.07 1.03 0.0333, 28.0 -0.74
C3H/HeJ f 32.2 13.2   20 2.95 0.41 6.8, 62.6 1.36
C3H/HeJ m 28.4 13.5   19 3.1 0.474 0.133, 48.1 1.11
C57BL/6J f 15.1 7.22   20 1.61 0.478 3.53, 33.1 -0.28
C57BL/6J m 12.7 4.81   20 1.07 0.378 3.13, 20.2 -0.38
CBA/J f 26.0 15.2   20 3.39 0.584 2.63, 51.3 0.76
CBA/J m 23.6 13.2   19 3.04 0.562 0.767, 49.8 0.65
DBA/2J f 8.21 6.63   20 1.48 0.807 -0.94
DBA/2J m 10.0 5.97   20 1.34 0.596 -0.64
FVB/NJ f 31.5 10.0   19 2.29 0.318 16.6, 49.1 1.29
FVB/NJ m 34.4 7.76   20 1.74 0.226 17.1, 46.2 1.67


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 13.1401 2.5218 18.1027 8.1776
129S1/SvImJ m 9.4025 2.5218 14.3651 4.44
A/J f 5.4264 2.5218 10.3889 0.4638
A/J m 6.2739 2.5218 11.2364 1.3113
BALB/cByJ f 12.8147 2.5218 17.7772 7.8521
BALB/cByJ m 8.9447 2.5218 13.9072 3.9821
C3H/HeJ f 32.175 2.5218 37.1376 27.2124
C3H/HeJ m 28.4438 2.5873 33.5353 23.3524
C57BL/6J f 15.098 2.5218 20.0606 10.1354
C57BL/6J m 12.713 2.5218 17.6756 7.7504
CBA/J f 25.9695 2.5218 30.9321 21.0069
CBA/J m 23.5683 2.5873 28.6597 18.4768
DBA/2J f 8.2095 2.5218 13.1721 3.2469
DBA/2J m 10.0295 2.5218 14.9921 5.0669
FVB/NJ f 31.4632 2.5873 36.5546 26.3717
FVB/NJ m 34.405 2.5218 39.3676 29.4424


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 11.2713 1.7832 14.7804 7.7623
A/J both 5.8501 1.7832 9.3592 2.341
BALB/cByJ both 10.8797 1.7832 14.3887 7.3706
C3H/HeJ both 30.3094 1.8065 33.8644 26.7545
C57BL/6J both 13.9055 1.7832 17.4146 10.3964
CBA/J both 24.7689 1.8065 28.3238 21.2139
DBA/2J both 9.1195 1.7832 12.6286 5.6104
FVB/NJ both 32.9341 1.8065 36.489 29.3791




  GWAS USING LINEAR MIXED MODELS