Project measure / variable:   Schoonjans1   THDCA_liver_HFD

ID, description, units MPD:112846   THDCA_liver_HFD   bile acid taurohyodeoxycholic acid amount in liver, at 29 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 29wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid taurohyodeoxycholic acid amount in liver, at 29 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.89726   ng/mL
Median of the strain means0.72482   ng/mL
SD of the strain means± 0.62104
Coefficient of variation (CV)0.6922
Min–max range of strain means0.39299   –   3.2453   ng/mL
Mean sample size per strain4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 62.8387 1.7954 7.9887 < 0.0001
Residuals 141 31.6887 0.2247


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 3.2453 0.87771   5 0.39252 0.2705 2.2146, 3.9528 3.78
BXD100 m 0.39965 0.1132   7 0.04279 0.2833 0.22787, 0.53773 -0.8
BXD11 m 1.051 0.83339   3 0.48116 0.793 0.49601, 2.0093 0.25
BXD12 m 2.2511 1.6544   4 0.8272 0.7349 0.50901, 4.4631 2.18
BXD27 m 0.54079 0.2851   5 0.1275 0.5272 0.34107, 1.0206 -0.57
BXD32 m 0.56376 0.15242   4 0.07621 0.2704 0.40024, 0.75534 -0.54
BXD34 m 2.2658 1.2845   4 0.64224 0.5669 1.2156, 4.1379 2.2
BXD39 m 0.6859 0.18431   5 0.08243 0.2687 0.44505, 0.92426 -0.34
BXD40 m 0.41678 0.15354   5 0.06866 0.3684 0.2677, 0.5982 -0.77
BXD43 m 0.55496 0.30746   5 0.1375 0.554 0.30031, 1.0689 -0.55
BXD45 m 0.85718 0.3034   5 0.13568 0.354 0.45316, 1.1989 -0.06
BXD48 m 1.0671 0.46283   5 0.20698 0.4337 0.41207, 1.672 0.27
BXD48a m 0.95771 0.34997   5 0.15651 0.3654 0.66671, 1.5238 0.1
BXD49 m 0.63204 0.39549   5 0.17687 0.6257 0.23452, 1.2496 -0.43
BXD51 m 0.61178 0.13757   5 0.06152 0.2249 0.47921, 0.76349 -0.46
BXD53 m 0.40304 0.14576   5 0.06518 0.3616 0.18884, 0.54872 -0.8
BXD55 m 0.46373 0.16065   5 0.07185 0.3464 0.27507, 0.64413 -0.7
BXD6 m 0.44272 0.15118   5 0.06761 0.3415 0.27722, 0.6595 -0.73
BXD62 m 0.41255 0.18408   5 0.08232 0.4462 0.25022, 0.69059 -0.78
BXD63 m 0.62797 0.10635   5 0.04756 0.1693 0.51219, 0.78498 -0.43
BXD64 m 0.85756 0.37686   5 0.16854 0.4395 0.47839, 1.3695 -0.06
BXD66 m 0.83629 0.38502   9 0.12834 0.4604 0.36843, 1.4437 -0.1
BXD67 m 0.78442 0.29504   5 0.13195 0.3761 0.29437, 1.0473 -0.18
BXD69 m 0.77311 0.38639   5 0.1728 0.4998 0.45024, 1.4453 -0.2
BXD73 m 0.53711 0.12511   5 0.05595 0.2329 0.44163, 0.75561 -0.58
BXD75 m 1.7517 0.7284   4 0.3642 0.4158 1.0205, 2.6904 1.38
BXD77 m 0.39299 0.24629   5 0.11014 0.6267 0.12577, 0.75181 -0.81
BXD79 m 0.53689 0.36247   5 0.1621 0.6751 0.21541, 1.0183 -0.58
BXD8 m 1.1103 0.64017   4 0.32009 0.5766 0.48194, 2.0002 0.34
BXD81 m 0.87504 0.21892   5 0.0979 0.2502 0.72103, 1.2325 -0.04
BXD84 m 0.82727 0.38902   5 0.17398 0.4703 0.34124, 1.2901 -0.11
BXD87 m 0.6384 0.19372   5 0.08663 0.3034 0.47647, 0.89966 -0.42
BXD89 m 1.6614 0.7594   5 0.33961 0.4571 0.95103, 2.8893 1.23
BXD90 m 0.43067 0.11442   3 0.06606 0.2657 0.34644, 0.56093 -0.75
C57BL/6J m 1.0735 0.29596   5 0.13236 0.2757 0.59205, 1.3089 0.28
DBA/2J m 0.76374 0.17239   5 0.0771 0.2257 0.60738, 0.96396 -0.21


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 3.24534 0.2120106408 3.6644705118 2.8262094882
BXD100 m 0.3996471429 0.1791816952 0.7538770782 0.0454172075
BXD11 m 1.0509766667 0.2737045604 1.5920718307 0.5098815026
BXD12 m 2.2511025 0.2370351024 2.7197046579 1.7825003421
BXD27 m 0.540794 0.2120106408 0.9599245118 0.1216634882
BXD32 m 0.5637575 0.2370351024 1.0323596579 0.0951553421
BXD34 m 2.26585 0.2370351024 2.7344521579 1.7972478421
BXD39 m 0.685896 0.2120106408 1.1050265118 0.2667654882
BXD40 m 0.416778 0.2120106408 0.8359085118 -0.0023525118
BXD43 m 0.55496 0.2120106408 0.9740905118 0.1358294882
BXD45 m 0.85718 0.2120106408 1.2763105118 0.4380494882
BXD48 m 1.067132 0.2120106408 1.4862625118 0.6480014882
BXD48a m 0.957708 0.2120106408 1.3768385118 0.5385774882
BXD49 m 0.632044 0.2120106408 1.0511745118 0.2129134882
BXD51 m 0.611776 0.2120106408 1.0309065118 0.1926454882
BXD53 m 0.403038 0.2120106408 0.8221685118 -0.0160925118
BXD55 m 0.463728 0.2120106408 0.8828585118 0.0445974882
BXD6 m 0.442718 0.2120106408 0.8618485118 0.0235874882
BXD62 m 0.412552 0.2120106408 0.8316825118 -0.0065785118
BXD63 m 0.627972 0.2120106408 1.0471025118 0.2088414882
BXD64 m 0.857556 0.2120106408 1.2766865118 0.4384254882
BXD66 m 0.8362855556 0.1580234016 1.1486869942 0.5238841169
BXD67 m 0.784418 0.2120106408 1.2035485118 0.3652874882
BXD69 m 0.77311 0.2120106408 1.1922405118 0.3539794882
BXD73 m 0.537106 0.2120106408 0.9562365118 0.1179754882
BXD75 m 1.751675 0.2370351024 2.2202771579 1.2830728421
BXD77 m 0.392992 0.2120106408 0.8121225118 -0.0261385118
BXD79 m 0.536892 0.2120106408 0.9560225118 0.1177614882
BXD8 m 1.11029 0.2370351024 1.5788921579 0.6416878421
BXD81 m 0.87504 0.2120106408 1.2941705118 0.4559094882
BXD84 m 0.827266 0.2120106408 1.2463965118 0.4081354882
BXD87 m 0.638396 0.2120106408 1.0575265118 0.2192654882
BXD89 m 1.661386 0.2120106408 2.0805165118 1.2422554882
BXD90 m 0.4306666667 0.2737045604 0.9717618307 -0.1104284974
C57BL/6J m 1.073514 0.2120106408 1.4926445118 0.6543834882
DBA/2J m 0.763738 0.2120106408 1.1828685118 0.3446074882




  GWAS USING LINEAR MIXED MODELS