Project measure / variable:   Schoonjans1   GUDCA_liver_CD

ID, description, units MPD:112829   GUDCA_liver_CD   bile acid glycoursodeoxycholic acid amount in liver, at 29 wks   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   25 strains     sex: m     age: 29wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid glycoursodeoxycholic acid amount in liver, at 29 wks CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested25 strains
Mean of the strain means0.00339058   ng/mL
Median of the strain means0.00110958   ng/mL
SD of the strain means± 0.00863127
Coefficient of variation (CV)2.5457
Min–max range of strain means0.00074111   –   0.04421   ng/mL
Mean sample size per strain2.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 17 0.0002 0.0 0.8539 0.6267
Residuals 43 0.0005 0.0


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.0055798 0.00699156   3 0.00403658 1.253 0.00115385, 0.01364 0.25
BXD11 m 0.0009556 0.00013404   3 7.739e-05 0.1403 0.00086913, 0.00111 -0.28
BXD12 m 0.00577284 0.00904098   4 0.00452049 1.5661 0.0010402, 0.01933 0.28
BXD27 m 0.00492546 0.0070531   4 0.00352655 1.432 0.00103448, 0.01549 0.18
BXD34 m 0.00102421 0.00018998   5 8.496e-05 0.1855 0.00074627, 0.00124629 -0.27
BXD40 m 0.00144939 0.00115304   4 0.00057652 0.7955 0.00077304, 0.00317561 -0.22
BXD43 m 0.04421 0.0   1   0.0 0.0 0.04421, 0.04421 4.73
BXD45 m 0.00088057 0.0   1   0.0 0.0 0.00088057, 0.00088057 -0.29
BXD48 m 0.00123662 0.00057268   2   0.00040495 0.4631 0.00083168, 0.00164157 -0.25
BXD48a m 0.00108172 0.0002608   2   0.00018441 0.2411 0.00089731, 0.00126614 -0.27
BXD49 m 0.00145646 0.0   1   0.0 0.0 0.00145646, 0.00145646 -0.22
BXD51 m 0.00074111 0.0   1   0.0 0.0 0.00074111, 0.00074111 -0.31
BXD6 m 0.00165384 0.00051794   5 0.00023163 0.3132 0.00102374, 0.00226779 -0.2
BXD62 m 0.00089927 0.0001292   3 7.459e-05 0.1437 0.00075453, 0.00100295 -0.29
BXD64 m 0.00110958 0.00042021   2   0.00029714 0.3787 0.00081244, 0.00140671 -0.26
BXD66 m 0.00096774 0.0   1   0.0 0.0 0.00096774, 0.00096774 -0.28
BXD67 m 0.00094007 0.00019035   2   0.0001346 0.2025 0.00080547, 0.00107467 -0.28
BXD69 m 0.00090196 0.00013193   3 7.617e-05 0.1463 0.00077228, 0.00103604 -0.29
BXD75 m 0.000855 0.0   1   0.0 0.0 0.000855, 0.000855 -0.29
BXD77 m 0.00125053 0.00037116   4 0.00018558 0.2968 0.0008631, 0.00171131 -0.25
BXD79 m 0.00284537 0.0005904   3 0.00034087 0.2075 0.00218781, 0.00333 -0.06
BXD8 m 0.00112097 0.00014031   4 7.016e-05 0.1252 0.0009403, 0.00127849 -0.26
BXD84 m 0.00094303 0.0   1   0.0 0.0 0.00094303, 0.00094303 -0.28
BXD89 m 0.00113707 0.00036305   5 0.00016236 0.3193 0.00083418, 0.00159319 -0.26
C57BL/6J m 0.00082631 5.488e-05   3 3.169e-05 0.0664 0.00076471, 0.00087 -0.3


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.0055797967 0.001968437 0.0095495282 0.0016100651
BXD11 m 0.0009555967 0.001968437 0.0049253282 -0.0030141349
BXD12 m 0.005772835 0.0017047165 0.0092107234 0.0023349466
BXD27 m 0.004925455 0.0017047165 0.0083633434 0.0014875666
BXD34 m 0.001024206 0.0015247448 0.0040991469 -0.0020507349
BXD40 m 0.001449385 0.0017047165 0.0048872734 -0.0019885034
BXD48 m 0.001236625 0.0024108331 0.0060985334 -0.0036252834
BXD48a m 0.001081725 0.0024108331 0.0059436334 -0.0037801834
BXD6 m 0.001653844 0.0015247448 0.0047287849 -0.0014210969
BXD62 m 0.0008992733 0.001968437 0.0048690049 -0.0030704582
BXD64 m 0.001109575 0.0024108331 0.0059714834 -0.0037523334
BXD67 m 0.00094007 0.0024108331 0.0058019784 -0.0039218384
BXD69 m 0.0009019633 0.001968437 0.0048716949 -0.0030677682
BXD77 m 0.0012505275 0.0017047165 0.0046884159 -0.0021873609
BXD79 m 0.0028453667 0.001968437 0.0068150982 -0.0011243649
BXD8 m 0.0011209725 0.0017047165 0.0045588609 -0.0023169159
BXD89 m 0.001137074 0.0015247448 0.0042120149 -0.0019378669
C57BL/6J m 0.00082631 0.001968437 0.0047960416 -0.0031434216




  GWAS USING LINEAR MIXED MODELS