Project measure / variable:   Schoonjans1   THDCA_feces_HFD

ID, description, units MPD:112799   THDCA_feces_HFD   bile acid taurohyodeoxycholic acid amount in feces, at 24 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid taurohyodeoxycholic acid amount in feces, at 24 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.14171   ng/mL
Median of the strain means0.0479   ng/mL
SD of the strain means± 0.25319
Coefficient of variation (CV)1.7867
Min–max range of strain means0.00652301   –   1.3583   ng/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 11.1356 0.3182 4.329 < 0.0001
Residuals 136 9.9954 0.0735


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.45454 0.40811   5 0.18251 0.8979 0.08443, 1.0942 1.24
BXD100 m 0.09475 0.03502   4 0.01751 0.3695 0.07017, 0.1465 -0.19
BXD11 m 0.04694 0.04091   3 0.02362 0.8715 0.00266798, 0.08334 -0.37
BXD12 m 0.10589 0.05585   4 0.02792 0.5274 0.03015, 0.15874 -0.14
BXD27 m 0.17052 0.23028   6 0.09401 1.3505 0.0197, 0.63572 0.11
BXD32 m 0.01562 0.00814736   4 0.00407368 0.5215 0.0095334, 0.02701 -0.5
BXD34 m 0.04051 0.05658   4 0.02829 1.3967 0.00619048, 0.12447 -0.4
BXD39 m 0.01495 0.00820269   5 0.00366835 0.5486 0.00723425, 0.02572 -0.5
BXD40 m 0.01996 0.00911313   5 0.00407552 0.4565 0.00975957, 0.0333 -0.48
BXD43 m 0.05718 0.01975   5 0.00883467 0.3455 0.03503, 0.08184 -0.33
BXD45 m 0.00705466 0.00215521   5 0.00096384 0.3055 0.00452096, 0.01012 -0.53
BXD48 m 1.3583 0.99669   5 0.44573 0.7338 0.09487, 2.7252 4.8
BXD48a m 0.05718 0.0837   5 0.03743 1.4639 0.00874749, 0.20497 -0.33
BXD49 m 0.0345 0.01717   5 0.00767889 0.4977 0.01516, 0.06174 -0.42
BXD51 m 0.64041 0.39075   5 0.17475 0.6102 0.3747, 1.3301 1.97
BXD53 m 0.0342 0.02898   5 0.01296 0.8474 0.00488464, 0.08168 -0.42
BXD55 m 0.01776 0.00760109   5 0.00339931 0.428 0.00695481, 0.02787 -0.49
BXD6 m 0.01153 0.01266   5 0.00566269 1.0979 0.00098802, 0.03344 -0.51
BXD62 m 0.00652301 0.00400359   5 0.00179046 0.6138 0.00331818, 0.01318 -0.53
BXD63 m 0.07956 0.07089   5 0.0317 0.891 0.01653, 0.18355 -0.25
BXD64 m 0.02246 0.01486   5 0.00664645 0.6618 0.00784226, 0.04641 -0.47
BXD66 m 0.03369 0.02455   5 0.01098 0.7288 0.01323, 0.0725 -0.43
BXD67 m 0.0194 0.01761   5 0.00787393 0.9077 0.00602652, 0.04789 -0.48
BXD69 m 0.01937 0.01365   5 0.00610439 0.7046 0.01083, 0.04344 -0.48
BXD73 m 0.04886 0.04943   5 0.02211 1.0117 0.01266, 0.13558 -0.37
BXD75 m 0.37256 0.58   5 0.25938 1.5568 0.01121, 1.3931 0.91
BXD77 m 0.05364 0.02791   5 0.01248 0.5204 0.01007, 0.08322 -0.35
BXD79 m 0.01659 0.00412009   5 0.00184256 0.2483 0.01104, 0.02048 -0.49
BXD8 m 0.10699 0.05122   4 0.02561 0.4788 0.05719, 0.17287 -0.14
BXD81 m 0.3814 0.77712   5 0.34754 2.0376 0.00755203, 1.7703 0.95
BXD84 m 0.01692 0.00411933   3 0.0023783 0.2435 0.01405, 0.02164 -0.49
BXD87 m 0.11529 0.14851   5 0.06641 1.2881 0.02067, 0.37358 -0.1
BXD89 m 0.04397 0.04117   5 0.01841 0.9362 0.01405, 0.11499 -0.39
BXD90 m 0.16336 0.17814   5 0.07966 1.0904 0.02909, 0.44692 0.09
C57BL/6J m 0.23735 0.28291   5 0.12652 1.192 0.01371, 0.64587 0.38
DBA/2J m 0.182 0.13058   5 0.0584 0.7175 0.05263, 0.38097 0.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.454536 0.1212396458 0.6942947681 0.2147772319
BXD100 m 0.0947525 0.1355500448 0.3628109518 -0.1733059518
BXD11 m 0.0469359933 0.1565197097 0.3564632319 -0.2625912453
BXD12 m 0.105885 0.1355500448 0.3739434518 -0.1621734518
BXD27 m 0.1705166667 0.1106761481 0.3893854761 -0.0483521427
BXD32 m 0.01562189 0.1355500448 0.2836803418 -0.2524365618
BXD34 m 0.04050789 0.1355500448 0.3085663418 -0.2275505618
BXD39 m 0.014952434 0.1212396458 0.2547112021 -0.2248063341
BXD40 m 0.019961914 0.1212396458 0.2597206821 -0.2197968541
BXD43 m 0.057176 0.1212396458 0.2969347681 -0.1825827681
BXD45 m 0.007054664 0.1212396458 0.2468134321 -0.2327041041
BXD48 m 1.358278 0.1212396458 1.5980367681 1.1185192319
BXD48a m 0.05717794 0.1212396458 0.2969367081 -0.1825808281
BXD49 m 0.0345 0.1212396458 0.2742587681 -0.2052587681
BXD51 m 0.640406 0.1212396458 0.8801647681 0.4006472319
BXD53 m 0.034198928 0.1212396458 0.2739576961 -0.2055598401
BXD55 m 0.017760962 0.1212396458 0.2575197301 -0.2219978061
BXD6 m 0.011532644 0.1212396458 0.2512914121 -0.2282261241
BXD62 m 0.006523006 0.1212396458 0.2462817741 -0.2332357621
BXD63 m 0.07956 0.1212396458 0.3193187681 -0.1601987681
BXD64 m 0.022458452 0.1212396458 0.2622172201 -0.2173003161
BXD66 m 0.03369 0.1212396458 0.2734487681 -0.2060687681
BXD67 m 0.01939775 0.1212396458 0.2591565181 -0.2203610181
BXD69 m 0.019372 0.1212396458 0.2591307681 -0.2203867681
BXD73 m 0.04886 0.1212396458 0.2886187681 -0.1908987681
BXD75 m 0.372558 0.1212396458 0.6123167681 0.1327992319
BXD77 m 0.05364 0.1212396458 0.2933987681 -0.1861187681
BXD79 m 0.016592 0.1212396458 0.2563507681 -0.2231667681
BXD8 m 0.10699 0.1355500448 0.3750484518 -0.1610684518
BXD81 m 0.381400406 0.1212396458 0.6211591741 0.1416416379
BXD84 m 0.01692 0.1565197097 0.3264472386 -0.2926072386
BXD87 m 0.115292 0.1212396458 0.3550507681 -0.1244667681
BXD89 m 0.043972 0.1212396458 0.2837307681 -0.1957867681
BXD90 m 0.163364 0.1212396458 0.4031227681 -0.0763947681
C57BL/6J m 0.237346 0.1212396458 0.4771047681 -0.0024127681
DBA/2J m 0.181998 0.1212396458 0.4217567681 -0.0577607681




  GWAS USING LINEAR MIXED MODELS