Project measure / variable:   Schoonjans1   GCDCA_feces_HFD

ID, description, units MPD:112773   GCDCA_feces_HFD   bile acid glycochenodeoxycholic acid amount in feces, at 24 wks   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   30 strains     sex: m     age: 24wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid glycochenodeoxycholic acid amount in feces, at 24 wks HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested30 strains
Mean of the strain means0.063   ng/mL
Median of the strain means0.07997   ng/mL
SD of the strain means± 0.02514
Coefficient of variation (CV)0.399
Min–max range of strain means0.00137703   –   0.08914   ng/mL
Mean sample size per strain1.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 11 0.0105 0.001 0.4673 0.9003
Residuals 18 0.0369 0.002


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.03021 0.04838   3 0.02793 1.6014 0.0010102, 0.08606 -1.3
BXD12 m 0.03102 0.0   1   0.0 0.0 0.03102, 0.03102 -1.27
BXD27 m 0.08821 0.00600334   2   0.004245 0.0681 0.08396, 0.09245 1.0
BXD32 m 0.04532 0.05404   2   0.03821 1.1923 0.00711167, 0.08353 -0.7
BXD39 m 0.08385 0.0   1   0.0 0.0 0.08385, 0.08385 0.83
BXD40 m 0.0792 0.0   1   0.0 0.0 0.0792, 0.0792 0.64
BXD43 m 0.04096 0.05383   2   0.03807 1.3141 0.00289941, 0.07903 -0.88
BXD45 m 0.08204 0.0   1   0.0 0.0 0.08204, 0.08204 0.76
BXD48 m 0.04257 0.04507   3 0.02602 1.0589 0.00856505, 0.09369 -0.81
BXD48a m 0.02348 0.04147   4 0.02074 1.7662 0.0006319, 0.08563 -1.57
BXD49 m 0.07972 0.0   1   0.0 0.0 0.07972, 0.07972 0.67
BXD51 m 0.0839 0.0   1   0.0 0.0 0.0839, 0.0839 0.83
BXD53 m 0.04492 0.05528   2   0.03909 1.2306 0.00583082, 0.08401 -0.72
BXD55 m 0.08178 0.0   1   0.0 0.0 0.08178, 0.08178 0.75
BXD6 m 0.08169 0.0   1   0.0 0.0 0.08169, 0.08169 0.74
BXD62 m 0.08022 0.0   1   0.0 0.0 0.08022, 0.08022 0.69
BXD63 m 0.04139 0.05703   2   0.04033 1.378 0.00106061, 0.08172 -0.86
BXD64 m 0.0805 0.0   1   0.0 0.0 0.0805, 0.0805 0.7
BXD66 m 0.08035 0.0   1   0.0 0.0 0.08035, 0.08035 0.69
BXD67 m 0.03872 0.05435   2   0.03843 1.4038 0.00028586, 0.07715 -0.97
BXD69 m 0.08203 0.0   1   0.0 0.0 0.08203, 0.08203 0.76
BXD73 m 0.03003 0.04834   3 0.02791 1.6094 0.00043988, 0.08581 -1.31
BXD75 m 0.08241 0.0   1   0.0 0.0 0.08241, 0.08241 0.77
BXD77 m 0.04152 0.05618   2   0.03972 1.3532 0.00179126, 0.08124 -0.85
BXD79 m 0.08154 0.0   1   0.0 0.0 0.08154, 0.08154 0.74
BXD81 m 0.08914 0.0   1   0.0 0.0 0.08914, 0.08914 1.04
BXD87 m 0.0795 0.0   1   0.0 0.0 0.0795, 0.0795 0.66
BXD89 m 0.08136 0.0   1   0.0 0.0 0.08136, 0.08136 0.73
C57BL/6J m 0.00137703 0.00072597   3 0.00041914 0.5272 0.00063798, 0.00208918 -2.45
DBA/2J m 0.08106 0.0   1   0.0 0.0 0.08106, 0.08106 0.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.03021221 0.0261235573 0.0850957672 -0.0246713472
BXD27 m 0.088205 0.0319946928 0.1554233552 0.0209866448
BXD32 m 0.045320835 0.0319946928 0.1125391902 -0.0218975202
BXD43 m 0.040964705 0.0319946928 0.1081830602 -0.0262536502
BXD48 m 0.0425650167 0.0261235573 0.0974485739 -0.0123185405
BXD48a m 0.0234825325 0.0226236642 0.0710130873 -0.0240480223
BXD53 m 0.04492041 0.0319946928 0.1121387652 -0.0222979452
BXD63 m 0.041390305 0.0319946928 0.1086086602 -0.0258280502
BXD67 m 0.03871793 0.0319946928 0.1059362852 -0.0285004252
BXD73 m 0.0300321367 0.0261235573 0.0849156939 -0.0248514205
BXD77 m 0.04151563 0.0319946928 0.1087339852 -0.0257027252
C57BL/6J m 0.0013770333 0.0261235573 0.0562605905 -0.0535065239




  GWAS USING LINEAR MIXED MODELS