Project measure / variable:   Schoonjans1   oxo_CA_feces_CD

ID, description, units MPD:112754   oxo_CA_feces_CD   bile acid 3-oxocholic acid amount in feces, at 24 wks   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Schoonjans1 - bile acid 3-oxocholic acid amount in feces, at 24 wks CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.1734   ng/mL
Median of the strain means0.1132   ng/mL
SD of the strain means± 0.21933
Coefficient of variation (CV)1.2649
Min–max range of strain means0.01439   –   1.2062   ng/mL
Mean sample size per strain4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 8.2868 0.2368 5.0727 < 0.0001
Residuals 139 6.4878 0.0467


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.27143 0.11215   5 0.05015 0.4132 0.18244, 0.46371 0.45
BXD100 m 0.18469 0.03426   5 0.01532 0.1855 0.1423, 0.23404 0.05
BXD11 m 0.13313 0.10417   4 0.05209 0.7825 0.00742485, 0.25855 -0.18
BXD12 m 0.04009 0.00523058   4 0.00261529 0.1305 0.03362, 0.0464 -0.61
BXD27 m 0.11224 0.04688   4 0.02344 0.4176 0.04743, 0.15955 -0.28
BXD32 m 0.09332 0.039   4 0.0195 0.4179 0.06332, 0.14795 -0.37
BXD34 m 0.01439 0.00604141   4 0.0030207 0.4197 0.00733493, 0.0214 -0.72
BXD39 m 0.10564 0.04435   5 0.01983 0.4198 0.05922, 0.17794 -0.31
BXD40 m 0.08479 0.02138   5 0.00956173 0.2521 0.05689, 0.10668 -0.4
BXD43 m 0.11456 0.05132   4 0.02566 0.448 0.07312, 0.18905 -0.27
BXD45 m 0.05008 0.03401   3 0.01964 0.6792 0.02279, 0.08818 -0.56
BXD48 m 0.11962 0.08753   5 0.03915 0.7318 0.06131, 0.26608 -0.25
BXD48a m 0.54845 0.34497   4 0.17248 0.629 0.18868, 0.88681 1.71
BXD49 m 0.06615 0.0104   5 0.00465053 0.1572 0.0556, 0.08314 -0.49
BXD51 m 0.55578 0.40124   5 0.17944 0.7219 0.14706, 1.1979 1.74
BXD53 m 0.01872 0.0062772   5 0.00280725 0.3353 0.00833665, 0.02462 -0.71
BXD55 m 0.08133 0.03554   5 0.01589 0.437 0.03881, 0.13097 -0.42
BXD6 m 1.2062 0.72829   5 0.3257 0.6038 0.04941, 2.0521 4.71
BXD62 m 0.14246 0.07287   5 0.03259 0.5116 0.05523, 0.21229 -0.14
BXD63 m 0.03322 0.00839905   5 0.00375617 0.2528 0.02518, 0.04225 -0.64
BXD64 m 0.06978 0.01859   5 0.00831438 0.2664 0.0477, 0.09863 -0.47
BXD66 m 0.13265 0.06101   5 0.02728 0.4599 0.0595, 0.20164 -0.19
BXD67 m 0.15757 0.01903   4 0.00951445 0.1208 0.13679, 0.1824 -0.07
BXD69 m 0.07049 0.0307   5 0.01373 0.4355 0.04463, 0.1101 -0.47
BXD73 m 0.10884 0.07826   5 0.035 0.7191 0.04795, 0.20575 -0.29
BXD75 m 0.14294 0.12027   5 0.05379 0.8414 0.04624, 0.31553 -0.14
BXD77 m 0.11416 0.08462   5 0.03784 0.7412 0.0644, 0.26494 -0.27
BXD79 m 0.19314 0.05414   5 0.02421 0.2803 0.10258, 0.2434 0.09
BXD8 m 0.0377 0.0283   5 0.01266 0.7507 0.01992, 0.08717 -0.62
BXD81 m 0.30355 0.57699   5 0.25804 1.9008 0.03236, 1.3356 0.59
BXD84 m 0.03036 0.00936232   5 0.00418696 0.3083 0.01996, 0.04562 -0.65
BXD87 m 0.08219 0.02246   5 0.01005 0.2733 0.06123, 0.119 -0.42
BXD89 m 0.20707 0.23676   5 0.10588 1.1434 0.06445, 0.62483 0.15
BXD90 m 0.39632 0.60111   5 0.26882 1.5167 0.07546, 1.4654 1.02
C57BL/6J m 0.03308 0.0195   10 0.00616492 0.5894 0.02071, 0.08708 -0.64
DBA/2J m 0.1864 0.09286   5 0.04153 0.4982 0.05745, 0.29614 0.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.271432 0.0966173799 0.4624617314 0.0804022686
BXD100 m 0.184694 0.0966173799 0.3757237314 -0.0063357314
BXD11 m 0.1331287125 0.1080215146 0.346706445 -0.08044902
BXD12 m 0.04009 0.1080215146 0.2536677325 -0.1734877325
BXD27 m 0.1122425 0.1080215146 0.3258202325 -0.1013352325
BXD32 m 0.09332 0.1080215146 0.3068977325 -0.1202577325
BXD34 m 0.0143937325 0.1080215146 0.227971465 -0.199184
BXD39 m 0.105638 0.0966173799 0.2966677314 -0.0853917314
BXD40 m 0.084794 0.0966173799 0.2758237314 -0.1062357314
BXD43 m 0.1145575 0.1080215146 0.3281352325 -0.0990202325
BXD45 m 0.0500766667 0.1247325011 0.2966949894 -0.1965416561
BXD48 m 0.119618 0.0966173799 0.3106477314 -0.0714117314
BXD48a m 0.5484475 0.1080215146 0.7620252325 0.3348697675
BXD49 m 0.066148 0.0966173799 0.2571777314 -0.1248817314
BXD51 m 0.55578 0.0966173799 0.7468097314 0.3647502686
BXD53 m 0.01872333 0.0966173799 0.2097530614 -0.1723064014
BXD55 m 0.08133 0.0966173799 0.2723597314 -0.1096997314
BXD6 m 1.206202 0.0966173799 1.3972317314 1.0151722686
BXD62 m 0.142458 0.0966173799 0.3334877314 -0.0485717314
BXD63 m 0.033224 0.0966173799 0.2242537314 -0.1578057314
BXD64 m 0.06978 0.0966173799 0.2608097314 -0.1212497314
BXD66 m 0.13265 0.0966173799 0.3236797314 -0.0583797314
BXD67 m 0.1575725 0.1080215146 0.3711502325 -0.0560052325
BXD69 m 0.070492 0.0966173799 0.2615217314 -0.1205377314
BXD73 m 0.108838 0.0966173799 0.2998677314 -0.0821917314
BXD75 m 0.142942 0.0966173799 0.3339717314 -0.0480877314
BXD77 m 0.114156 0.0966173799 0.3051857314 -0.0768737314
BXD79 m 0.193136 0.0966173799 0.3841657314 0.0021062686
BXD8 m 0.037704 0.0966173799 0.2287337314 -0.1533257314
BXD81 m 0.30355 0.0966173799 0.4945797314 0.1125202686
BXD84 m 0.030364 0.0966173799 0.2213937314 -0.1606657314
BXD87 m 0.082186 0.0966173799 0.2732157314 -0.1088437314
BXD89 m 0.207068 0.0966173799 0.3980977314 0.0160382686
BXD90 m 0.396322 0.0966173799 0.5873517314 0.2052922686
C57BL/6J m 0.033077 0.0683188045 0.1681554184 -0.1020014184
DBA/2J m 0.1864 0.0966173799 0.3774297314 -0.0046297314




  GWAS USING LINEAR MIXED MODELS