Project measure / variable:   Schoonjans1   wMCA_plasma_t60_CD

ID, description, units MPD:112752   wMCA_plasma_t60_CD   plasma bile acid ω-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 24wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid ω-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means61.39   ng/mL
Median of the strain means52.1   ng/mL
SD of the strain means± 35.061
Coefficient of variation (CV)0.5711
Min–max range of strain means22.333   –   153.7   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 203777.7931 5822.2227 2.5161 < 0.0001
Residuals 130 300820.5585 2314.0043


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 28.036 6.882   5 3.0777 0.2455 20.45, 35.974 -0.95
BXD100 m 30.963 16.186   5 7.2388 0.5228 18.394, 56.64 -0.87
BXD11 m 47.405 15.712   4 7.856 0.3314 33.282, 63.38 -0.4
BXD12 m 55.7 48.42   3 27.956 0.8693 19.93, 110.8 -0.16
BXD27 m 47.337 4.7716   4 2.3858 0.1008 43.359, 54.0 -0.4
BXD32 m 113.0 144.4   5 64.57 1.2776 34.526, 370.3 1.47
BXD34 m 33.334 12.727   5 5.6918 0.3818 20.128, 54.19 -0.8
BXD39 m 49.075 29.031   3 16.761 0.5916 19.554, 77.59 -0.35
BXD40 m 153.7 109.7   4 54.83 0.7132 64.77, 313.8 2.63
BXD43 m 23.517 12.306   7 4.6513 0.5233 9.096, 41.964 -1.08
BXD45 m 75.02 61.96   4 30.979 0.8259 24.934, 158.5 0.39
BXD48 m 89.79 26.032   5 11.642 0.2899 53.14, 116.3 0.81
BXD48a m 68.07 14.644   4 7.3218 0.2151 50.1, 83.62 0.19
BXD49 m 49.442 26.094   5 11.67 0.5278 17.986, 78.21 -0.34
BXD51 m 22.333 16.026   5 7.1668 0.7176 8.614, 48.4 -1.11
BXD53 m 102.7 30.232   4 15.116 0.2944 58.2, 123.1 1.18
BXD55 m 40.565 23.82   5 10.653 0.5872 20.62, 73.0 -0.59
BXD6 m 139.7 77.9   5 34.836 0.5575 67.64, 225.3 2.23
BXD62 m 74.07 39.889   5 17.839 0.5386 27.158, 132.3 0.36
BXD63 m 23.489 7.4151   4 3.7075 0.3157 13.484, 29.364 -1.08
BXD64 m 55.11 11.984   5 5.3593 0.2175 38.712, 71.22 -0.18
BXD66 m 47.111 14.27   5 6.382 0.3029 24.136, 62.17 -0.41
BXD67 m 49.142 26.727   4 13.363 0.5439 20.19, 80.56 -0.35
BXD69 m 32.463 21.729   5 9.7174 0.6693 14.082, 67.49 -0.82
BXD73 m 70.12 23.458   4 11.729 0.3346 49.182, 102.2 0.25
BXD75 m 81.25 16.225   5 7.2559 0.1997 62.12, 105.0 0.57
BXD77 m 147.4 128.2   5 57.34 0.8695 42.452, 348.0 2.45
BXD79 m 93.16 60.28   5 26.959 0.6471 26.304, 184.9 0.91
BXD8 m 57.24 18.376   5 8.218 0.321 40.368, 85.19 -0.12
BXD81 m 69.65 74.87   3 43.224 1.0748 26.096, 156.1 0.24
BXD84 m 33.957 11.499   5 5.1426 0.3386 17.888, 47.136 -0.78
BXD87 m 67.3 34.112   5 15.255 0.5069 42.21, 124.3 0.17
BXD89 m 34.204 33.071   5 14.79 0.9669 8.058, 71.72 -0.78
BXD90 m 23.597 25.052   5 11.203 1.0616 5.61, 66.28 -1.08
C57BL/6J m 54.75 29.659   5 13.264 0.5417 27.932, 89.56 -0.19
DBA/2J m 26.25 11.281   4 5.6407 0.4298 13.144, 40.674 -1.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 28.0364 21.5128068647 70.5969155673 -14.5241155673
BXD100 m 30.9628 21.5128068647 73.5233155673 -11.5977155673
BXD11 m 47.405 24.0520492681 94.9891029829 -0.1791029829
BXD12 m 55.7006666667 27.772914239 110.6460559994 0.755277334
BXD27 m 47.33675 24.0520492681 94.9208529829 -0.2473529829
BXD32 m 113.0216 21.5128068647 155.5821155673 70.4610844327
BXD34 m 33.3344 21.5128068647 75.8949155673 -9.2261155673
BXD39 m 49.0746666667 27.772914239 104.0200559994 -5.870722666
BXD40 m 153.7425 24.0520492681 201.3266029829 106.1583970171
BXD43 m 23.5168571429 18.1816402528 59.487057958 -12.4533436723
BXD45 m 75.0185 24.0520492681 122.6026029829 27.4343970171
BXD48 m 89.788 21.5128068647 132.3485155673 47.2274844327
BXD48a m 68.07 24.0520492681 115.6541029829 20.4858970171
BXD49 m 49.4416 21.5128068647 92.0021155673 6.8810844327
BXD51 m 22.3328 21.5128068647 64.8933155673 -20.2277155673
BXD53 m 102.7 24.0520492681 150.2841029829 55.1158970171
BXD55 m 40.5652 21.5128068647 83.1257155673 -1.9953155673
BXD6 m 139.736 21.5128068647 182.2965155673 97.1754844327
BXD62 m 74.0656 21.5128068647 116.6261155673 31.5050844327
BXD63 m 23.489 24.0520492681 71.0731029829 -24.0951029829
BXD64 m 55.1104 21.5128068647 97.6709155673 12.5498844327
BXD66 m 47.1108 21.5128068647 89.6713155673 4.5502844327
BXD67 m 49.1415 24.0520492681 96.7256029829 1.5573970171
BXD69 m 32.4632 21.5128068647 75.0237155673 -10.0973155673
BXD73 m 70.1155 24.0520492681 117.6996029829 22.5313970171
BXD75 m 81.254 21.5128068647 123.8145155673 38.6934844327
BXD77 m 147.4484 21.5128068647 190.0089155673 104.8878844327
BXD79 m 93.1568 21.5128068647 135.7173155673 50.5962844327
BXD8 m 57.2412 21.5128068647 99.8017155673 14.6806844327
BXD81 m 69.6533333333 27.772914239 124.598722666 14.7079440006
BXD84 m 33.9568 21.5128068647 76.5173155673 -8.6037155673
BXD87 m 67.2968 21.5128068647 109.8573155673 24.7362844327
BXD89 m 34.2044 21.5128068647 76.7649155673 -8.3561155673
BXD90 m 23.5972 21.5128068647 66.1577155673 -18.9633155673
C57BL/6J m 54.7496 21.5128068647 97.3101155673 12.1890844327
DBA/2J m 26.25 24.0520492681 73.8341029829 -21.3341029829




  GWAS USING LINEAR MIXED MODELS