Project measure / variable:   Schoonjans1   TaMCA_plasma_t60_CD

ID, description, units MPD:112736   TaMCA_plasma_t60_CD   plasma bile acid tauro-α-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid tauro-α-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means60.23   ng/mL
Median of the strain means62.94   ng/mL
SD of the strain means± 29.267
Coefficient of variation (CV)0.4859
Min–max range of strain means13.621   –   142.3   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 137511.0397 3928.8868 1.3471 0.118
Residuals 130 379155.3393 2916.5795


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 20.412 10.047   5 4.4932 0.4922 7.206, 32.296 -1.36
BXD100 m 72.71 14.748   5 6.5954 0.2028 52.0, 85.5 0.43
BXD11 m 72.14 60.43   4 30.213 0.8376 12.906, 154.6 0.41
BXD12 m 89.43 52.0   3 30.02 0.5814 43.728, 146.0 1.0
BXD27 m 73.66 98.88   4 49.438 1.3423 15.58, 221.1 0.46
BXD32 m 62.16 51.09   5 22.848 0.8219 9.256, 131.4 0.07
BXD34 m 29.642 11.768   5 5.2627 0.397 15.504, 42.448 -1.05
BXD39 m 61.9 59.0   3 34.065 0.9532 17.296, 128.8 0.06
BXD40 m 67.75 26.877   4 13.438 0.3967 33.878, 92.22 0.26
BXD43 m 22.195 24.126   7 9.1189 1.087 3.784, 72.98 -1.3
BXD45 m 98.61 26.955   4 13.478 0.2733 69.0, 132.1 1.31
BXD48 m 70.64 71.05   5 31.774 1.0058 23.69, 195.4 0.36
BXD48a m 79.38 86.55   4 43.275 1.0904 5.084, 193.5 0.65
BXD49 m 63.73 21.565   5 9.644 0.3384 37.062, 88.16 0.12
BXD51 m 52.45 24.445   5 10.932 0.4661 26.746, 84.77 -0.27
BXD53 m 95.59 73.0   4 36.499 0.7637 12.376, 169.8 1.21
BXD55 m 28.243 18.61   5 8.3226 0.6589 12.114, 53.83 -1.09
BXD6 m 142.3 181.8   5 81.31 1.2779 9.696, 446.2 2.8
BXD62 m 54.36 30.154   5 13.485 0.5547 26.024, 92.94 -0.2
BXD63 m 23.051 16.296   4 8.1481 0.707 6.874, 37.122 -1.27
BXD64 m 67.25 29.737   5 13.299 0.4422 30.45, 96.34 0.24
BXD66 m 47.825 31.692   5 14.173 0.6627 21.836, 100.8 -0.42
BXD67 m 23.877 23.995   4 11.997 1.0049 7.618, 59.4 -1.24
BXD69 m 78.8 36.452   5 16.302 0.4626 34.202, 124.8 0.63
BXD73 m 95.76 109.9   4 54.97 1.1481 26.324, 257.6 1.21
BXD75 m 75.73 73.06   5 32.674 0.9648 16.01, 168.5 0.53
BXD77 m 44.032 26.55   5 11.874 0.603 12.144, 68.85 -0.55
BXD79 m 72.54 24.197   5 10.821 0.3336 47.79, 111.7 0.42
BXD8 m 86.34 28.945   5 12.945 0.3353 50.97, 129.4 0.89
BXD81 m 13.621 9.8657   3 5.696 0.7243 6.908, 24.948 -1.59
BXD84 m 51.23 18.323   5 8.1944 0.3577 31.386, 72.86 -0.31
BXD87 m 30.023 12.248   5 5.4774 0.4079 12.864, 44.844 -1.03
BXD89 m 50.37 50.39   5 22.535 1.0003 16.154, 138.7 -0.34
BXD90 m 29.536 28.58   5 12.781 0.9676 7.67, 76.24 -1.05
C57BL/6J m 102.4 46.157   5 20.642 0.4507 45.736, 174.7 1.44
DBA/2J m 18.746 14.804   4 7.4019 0.7897 4.282, 38.848 -1.42


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 20.4124 24.1519338084 68.1941126002 -27.3693126002
BXD100 m 72.71 24.1519338084 120.4917126002 24.9282873998
BXD11 m 72.143 27.0026828918 125.5645787277 18.7214212723
BXD12 m 89.426 31.1800124729 151.1119257179 27.7400742821
BXD27 m 73.66175 27.0026828918 127.0833287277 20.2401712723
BXD32 m 62.1624 24.1519338084 109.9441126002 14.3806873998
BXD34 m 29.6416 24.1519338084 77.4233126002 -18.1401126002
BXD39 m 61.8973333333 31.1800124729 123.5832590513 0.2114076154
BXD40 m 67.752 27.0026828918 121.1735787277 14.3304212723
BXD43 m 22.1948571429 20.4121096181 62.5777748451 -18.1880605594
BXD45 m 98.6125 27.0026828918 152.0340787277 45.1909212723
BXD48 m 70.6396 24.1519338084 118.4213126002 22.8578873998
BXD48a m 79.3775 27.0026828918 132.7990787277 25.9559212723
BXD49 m 63.7288 24.1519338084 111.5105126002 15.9470873998
BXD51 m 52.4468 24.1519338084 100.2285126002 4.6650873998
BXD53 m 95.5865 27.0026828918 149.0080787277 42.1649212723
BXD55 m 28.2432 24.1519338084 76.0249126002 -19.5385126002
BXD6 m 142.2744 24.1519338084 190.0561126002 94.4926873998
BXD62 m 54.3624 24.1519338084 102.1441126002 6.5806873998
BXD63 m 23.051 27.0026828918 76.4725787277 -30.3705787277
BXD64 m 67.25 24.1519338084 115.0317126002 19.4682873998
BXD66 m 47.8248 24.1519338084 95.6065126002 0.0430873998
BXD67 m 23.8775 27.0026828918 77.2990787277 -29.5440787277
BXD69 m 78.8004 24.1519338084 126.5821126002 31.0186873998
BXD73 m 95.759 27.0026828918 149.1805787277 42.3374212723
BXD75 m 75.7264 24.1519338084 123.5081126002 27.9446873998
BXD77 m 44.0324 24.1519338084 91.8141126002 -3.7493126002
BXD79 m 72.536 24.1519338084 120.3177126002 24.7542873998
BXD8 m 86.336 24.1519338084 134.1177126002 38.5542873998
BXD81 m 13.6206666667 31.1800124729 75.3065923846 -48.0652590513
BXD84 m 51.2276 24.1519338084 99.0093126002 3.4458873998
BXD87 m 30.0232 24.1519338084 77.8049126002 -17.7585126002
BXD89 m 50.3732 24.1519338084 98.1549126002 2.5914873998
BXD90 m 29.536 24.1519338084 77.3177126002 -18.2457126002
C57BL/6J m 102.4032 24.1519338084 150.1849126002 54.6214873998
DBA/2J m 18.7465 27.0026828918 72.1680787277 -34.6750787277




  GWAS USING LINEAR MIXED MODELS