Project measure / variable:   Schoonjans1   oxo_CA_plasma_t60_CD

ID, description, units MPD:112718   oxo_CA_plasma_t60_CD   plasma bile acid 3-oxocholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   12 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid 3-oxocholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested12 strains
Mean of the strain means4.8007   ng/mL
Median of the strain means4.724   ng/mL
SD of the strain means± 1.1399
Coefficient of variation (CV)0.2374
Min–max range of strain means2.81   –   6.935   ng/mL
Mean sample size per strain2.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 6 14.6617 2.4436 0.1893 0.974
Residuals 12 154.8961 12.908


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 4.246 0.0   1   0.0 0.0 4.246, 4.246 -0.49
BXD12 m 2.81 0.0   1   0.0 0.0 2.81, 2.81 -1.75
BXD32 m 5.5827 1.945   3 1.123 0.3484 4.314, 7.822 0.69
BXD40 m 5.336 0.0   1   0.0 0.0 5.336, 5.336 0.47
BXD45 m 3.572 0.0   1   0.0 0.0 3.572, 3.572 -1.08
BXD49 m 4.684 0.0   1   0.0 0.0 4.684, 4.684 -0.1
BXD55 m 4.457 1.6306   2   1.153 0.3658 3.304, 5.61 -0.3
BXD6 m 6.0525 4.7567   4 2.3784 0.7859 2.658, 13.068 1.1
BXD73 m 3.789 1.4071   2   0.995 0.3714 2.794, 4.784 -0.89
BXD77 m 6.935 5.9383   2   4.199 0.8563 2.736, 11.134 1.87
BXD87 m 4.764 2.6188   3 1.512 0.5497 2.962, 7.768 -0.03
C57BL/6J m 5.3807 3.5939   3 2.075 0.6679 3.18, 9.528 0.51


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD32 m 5.5826666667 2.074287872 10.1021516946 1.0631816387
BXD55 m 4.457 2.540473433 9.9922161093 -1.0782161093
BXD6 m 6.0525 1.7963859919 9.9664888462 2.1385111538
BXD73 m 3.789 2.540473433 9.3242161093 -1.7462161093
BXD77 m 6.935 2.540473433 12.4702161093 1.3997838907
BXD87 m 4.764 2.074287872 9.2834850279 0.2445149721
C57BL/6J m 5.3806666667 2.074287872 9.9001516946 0.8611816387




  GWAS USING LINEAR MIXED MODELS