Project measure / variable:   Schoonjans1   GCA_plasma_t30_HFD

ID, description, units MPD:112697   GCA_plasma_t30_HFD   plasma bile acid glycocholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   31 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid glycocholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested31 strains
Mean of the strain means1.1344   ng/mL
Median of the strain means0.6805   ng/mL
SD of the strain means± 1.1636
Coefficient of variation (CV)1.0258
Min–max range of strain means0.016   –   3.9524   ng/mL
Mean sample size per strain3.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 27 154.173 5.7101 2.6553 0.0004
Residuals 80 172.0342 2.1504


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 0.32546 0.28979   4 0.1449 0.8904 0.05, 0.6125 -0.7
BXD100 m 0.064 0.04521   3 0.0261 0.7064 0.012, 0.094 -0.92
BXD11 m 0.28 0.0   1   0.0 0.0 0.28, 0.28 -0.73
BXD12 m 0.4215 0.33823   4 0.16911 0.8024 0.02, 0.746 -0.61
BXD27 m 0.86667 1.4042   3 0.81073 1.6203 0.038, 2.488 -0.23
BXD32 m 1.167 0.84301   4 0.42151 0.7224 0.598, 2.392 0.03
BXD34 m 1.4195 1.5156   4 0.7578 1.0677 0.002, 3.228 0.25
BXD39 m 1.28 0.0   1   0.0 0.0 1.28, 1.28 0.13
BXD40 m 0.5145 0.25007   4 0.12504 0.4861 0.206, 0.812 -0.53
BXD45 m 0.172 0.15733   5 0.07036 0.9147 0.026, 0.404 -0.83
BXD48 m 0.31533 0.24736   3 0.14281 0.7844 0.09, 0.58 -0.7
BXD48a m 1.069 0.9091   4 0.45455 0.8504 0.4, 2.386 -0.06
BXD49 m 0.4764 0.31123   5 0.13919 0.6533 0.176, 0.962 -0.57
BXD51 m 0.11336 0.16043   3 0.09263 1.4152 0.008, 0.298 -0.88
BXD53 m 0.6805 0.74265   4 0.37133 1.0913 0.17, 1.782 -0.39
BXD55 m 0.8028 0.18989   5 0.08492 0.2365 0.53, 1.056 -0.28
BXD6 m 3.0451 2.9252   3 1.6889 0.9607 1.14, 6.4132 1.64
BXD63 m 0.9796 1.0001   5 0.44725 1.0209 0.086, 2.284 -0.13
BXD64 m 3.9524 0.93344   5 0.41745 0.2362 2.962, 5.306 2.42
BXD67 m 0.4044 0.2457   5 0.10988 0.6076 0.08, 0.656 -0.63
BXD69 m 2.8325 3.879   4 1.9395 1.3695 0.238, 8.6 1.46
BXD73 m 2.0393 0.42299   3 0.24421 0.2074 1.642, 2.484 0.78
BXD75 m 1.311 0.91445   4 0.45722 0.6975 0.41, 2.554 0.15
BXD77 m 2.1107 0.8031   3 0.46367 0.3805 1.644, 3.038 0.84
BXD79 m 0.238 0.32244   2   0.228 1.3548 0.01, 0.466 -0.77
BXD8 m 0.44533 0.34246   3 0.19772 0.769 0.058, 0.708 -0.59
BXD81 m 3.752 4.2104   5 1.8829 1.1222 1.184, 11.174 2.25
BXD84 m 0.309 0.29   4 0.145 0.9385 0.06, 0.728 -0.71
BXD89 m 0.2055 0.11589   4 0.05794 0.5639 0.07, 0.346 -0.8
BXD90 m 0.016 0.0   1   0.0 0.0 0.016, 0.016 -0.96
C57BL/6J m 3.5567 1.9574   3 1.1301 0.5504 2.032, 5.764 2.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 0.3254575 0.7332168852 1.784605603 -1.133690603
BXD100 m 0.064 0.846645932 1.7488791001 -1.6208791001
BXD12 m 0.4215 0.7332168852 1.880648103 -1.037648103
BXD27 m 0.8666666667 0.846645932 2.5515457668 -0.8182124335
BXD32 m 1.167 0.7332168852 2.626148103 -0.292148103
BXD34 m 1.4195 0.7332168852 2.878648103 -0.039648103
BXD40 m 0.5145 0.7332168852 1.973648103 -0.944648103
BXD45 m 0.172 0.655809119 1.477101739 -1.133101739
BXD48 m 0.3153333333 0.846645932 2.0002124335 -1.3695457668
BXD48a m 1.069 0.7332168852 2.528148103 -0.390148103
BXD49 m 0.4764 0.655809119 1.781501739 -0.828701739
BXD51 m 0.1133633333 0.846645932 1.7982424335 -1.5715157668
BXD53 m 0.6805 0.7332168852 2.139648103 -0.778648103
BXD55 m 0.8028 0.655809119 2.107901739 -0.502301739
BXD6 m 3.0450666667 0.846645932 4.7299457668 1.3601875665
BXD63 m 0.9796 0.655809119 2.284701739 -0.325501739
BXD64 m 3.9524 0.655809119 5.257501739 2.647298261
BXD67 m 0.4044 0.655809119 1.709501739 -0.900701739
BXD69 m 2.8325 0.7332168852 4.291648103 1.373351897
BXD73 m 2.0393333333 0.846645932 3.7242124335 0.3544542332
BXD75 m 1.311 0.7332168852 2.770148103 -0.148148103
BXD77 m 2.1106666667 0.846645932 3.7955457668 0.4257875665
BXD79 m 0.238 1.0369252632 2.3015470368 -1.8255470368
BXD8 m 0.4453333333 0.846645932 2.1302124335 -1.2395457668
BXD81 m 3.752 0.655809119 5.057101739 2.446898261
BXD84 m 0.309 0.7332168852 1.768148103 -1.150148103
BXD89 m 0.2055 0.7332168852 1.664648103 -1.253648103
C57BL/6J m 3.5566666667 0.846645932 5.2415457668 1.8717875665




  GWAS USING LINEAR MIXED MODELS