Project measure / variable:   Schoonjans1   CDCA_plasma_t30_CD

ID, description, units MPD:112692   CDCA_plasma_t30_CD   plasma bile acid chenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid chenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means3.135   ng/mL
Median of the strain means1.4748   ng/mL
SD of the strain means± 3.6878
Coefficient of variation (CV)1.1764
Min–max range of strain means0.14551   –   14.446   ng/mL
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 2243.6621 64.1046 2.8384 < 0.0001
Residuals 125 2823.0696 22.5846


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 1.7121 3.0896   5 1.3817 1.8046 0.19, 7.2344 -0.39
BXD100 m 2.0332 1.6424   5 0.73449 0.8078 0.668, 4.858 -0.3
BXD11 m 0.279 0.04562   4 0.02281 0.1635 0.226, 0.32 -0.77
BXD12 m 6.8587 7.7591   3 4.4797 1.1313 1.262, 15.716 1.01
BXD27 m 1.8275 1.455   4 0.7275 0.7962 0.53, 3.628 -0.35
BXD32 m 7.6964 12.234   5 5.4711 1.5895 0.734, 29.408 1.24
BXD34 m 2.546 0.91032   5 0.40711 0.3575 1.578, 3.768 -0.16
BXD39 m 0.86333 0.7419   3 0.42833 0.8593 0.434, 1.72 -0.62
BXD40 m 9.6 7.6259   4 3.813 0.7944 1.066, 17.102 1.75
BXD43 m 1.0845 1.0999   6 0.44904 1.0142 0.082, 3.1 -0.56
BXD45 m 3.1995 4.1179   4 2.059 1.287 0.436, 9.328 0.02
BXD48 m 0.8728 0.30956   5 0.13844 0.3547 0.612, 1.286 -0.61
BXD48a m 1.5135 0.08205   4 0.04102 0.0542 1.41, 1.594 -0.44
BXD49 m 8.3044 7.2525   5 3.2434 0.8733 0.752, 17.958 1.4
BXD51 m 0.8365 0.42763   4 0.21381 0.5112 0.32, 1.276 -0.62
BXD53 m 0.664 0.75252   4 0.37626 1.1333 0.116, 1.772 -0.67
BXD55 m 11.918 8.5217   5 3.811 0.715 5.672, 24.818 2.38
BXD6 m 14.446 11.641   5 5.2058 0.8058 4.896, 33.256 3.07
BXD62 m 0.9956 0.3739   5 0.16721 0.3755 0.54, 1.56 -0.58
BXD63 m 0.5145 0.19466   4 0.09733 0.3784 0.25, 0.718 -0.71
BXD64 m 0.5592 0.19937   5 0.08916 0.3565 0.286, 0.776 -0.7
BXD66 m 1.004 0.34529   5 0.15442 0.3439 0.702, 1.562 -0.58
BXD67 m 0.182 0.17168   4 0.08584 0.9433 0.026, 0.388 -0.8
BXD69 m 1.8456 3.0695   5 1.3727 1.6631 0.21, 7.31 -0.35
BXD73 m 5.042 7.0379   3 4.0634 1.3959 0.536, 13.152 0.52
BXD75 m 0.9508 0.63768   5 0.28518 0.6707 0.27, 1.972 -0.59
BXD77 m 10.209 11.494   5 5.1403 1.1259 2.682, 29.538 1.92
BXD79 m 1.2085 2.0019   4 1.0009 1.6565 0.07, 4.2 -0.52
BXD8 m 0.808 0.9048   5 0.40464 1.1198 0.148, 2.38 -0.63
BXD81 m 2.4477 1.9099   3 1.1027 0.7803 0.63, 4.438 -0.19
BXD84 m 0.14551 0.09946   5 0.04448 0.6835 0.028, 0.284 -0.81
BXD87 m 2.7944 2.353   5 1.0523 0.842 0.914, 6.788 -0.09
BXD89 m 1.436 1.0304   4 0.51522 0.7176 0.854, 2.98 -0.46
BXD90 m 1.0612 0.97134   5 0.4344 0.9153 0.054, 2.66 -0.56
C57BL/6J m 4.7128 3.4135   5 1.5266 0.7243 1.44, 9.458 0.43
DBA/2J m 0.6865 0.50048   4 0.25024 0.729 0.288, 1.382 -0.66


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 1.71208 2.125302669 5.9183177521 -2.4941577521
BXD100 m 2.0332 2.125302669 6.2394377521 -2.1730377521
BXD11 m 0.279 2.3761606204 4.9817167716 -4.4237167716
BXD12 m 6.8586666667 2.7437539476 12.2888962547 1.4284370786
BXD27 m 1.8275 2.3761606204 6.5302167716 -2.8752167716
BXD32 m 7.6964 2.125302669 11.9026377521 3.4901622479
BXD34 m 2.546 2.125302669 6.7522377521 -1.6602377521
BXD39 m 0.8633333333 2.7437539476 6.2935629214 -4.5668962547
BXD40 m 9.6 2.3761606204 14.3027167716 4.8972832284
BXD43 m 1.0845 1.9401270223 4.9242521651 -2.7552521651
BXD45 m 3.1995 2.3761606204 7.9022167716 -1.5032167716
BXD48 m 0.8728 2.125302669 5.0790377521 -3.3334377521
BXD48a m 1.5135 2.3761606204 6.2162167716 -3.1892167716
BXD49 m 8.3044 2.125302669 12.5106377521 4.0981622479
BXD51 m 0.8365 2.3761606204 5.5392167716 -3.8662167716
BXD53 m 0.664 2.3761606204 5.3667167716 -4.0387167716
BXD55 m 11.9184 2.125302669 16.1246377521 7.7121622479
BXD6 m 14.4456 2.125302669 18.6518377521 10.2393622479
BXD62 m 0.9956 2.125302669 5.2018377521 -3.2106377521
BXD63 m 0.5145 2.3761606204 5.2172167716 -4.1882167716
BXD64 m 0.5592 2.125302669 4.7654377521 -3.6470377521
BXD66 m 1.004 2.125302669 5.2102377521 -3.2022377521
BXD67 m 0.182 2.3761606204 4.8847167716 -4.5207167716
BXD69 m 1.8456 2.125302669 6.0518377521 -2.3606377521
BXD73 m 5.042 2.7437539476 10.4722295881 -0.3882295881
BXD75 m 0.9508 2.125302669 5.1570377521 -3.2554377521
BXD77 m 10.2092 2.125302669 14.4154377521 6.0029622479
BXD79 m 1.2085 2.3761606204 5.9112167716 -3.4942167716
BXD8 m 0.808 2.125302669 5.0142377521 -3.3982377521
BXD81 m 2.4476666667 2.7437539476 7.8778962547 -2.9825629214
BXD84 m 0.145506 2.125302669 4.3517437521 -4.0607317521
BXD87 m 2.7944 2.125302669 7.0006377521 -1.4118377521
BXD89 m 1.436 2.3761606204 6.1387167716 -3.2667167716
BXD90 m 1.0612 2.125302669 5.2674377521 -3.1450377521
C57BL/6J m 4.7128 2.125302669 8.9190377521 0.5065622479
DBA/2J m 0.6865 2.3761606204 5.3892167716 -4.0162167716




  GWAS USING LINEAR MIXED MODELS