Project measure / variable:   Schoonjans1   THDCA_plasma_t0_CD

ID, description, units MPD:112674   THDCA_plasma_t0_CD   plasma bile acid taurohyodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurohyodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means12.676   ng/mL
Median of the strain means10.584   ng/mL
SD of the strain means± 10.595
Coefficient of variation (CV)0.8359
Min–max range of strain means0.355   –   51.25   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 17797.6046 508.503 2.565 < 0.0001
Residuals 128 25376.0289 198.2502


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 3.45 1.2648   5 0.56565 0.3666 1.84, 4.91 -0.87
BXD100 m 5.5268 2.5533   5 1.1419 0.462 2.844, 8.708 -0.67
BXD11 m 2.9375 2.6132   4 1.3066 0.8896 0.272, 5.478 -0.92
BXD12 m 15.035 7.4813   3 4.3193 0.4976 8.332, 23.106 0.22
BXD27 m 7.4255 6.6656   4 3.3328 0.8977 2.058, 17.08 -0.5
BXD32 m 14.206 9.3993   5 4.2035 0.6617 4.47, 28.47 0.14
BXD34 m 11.019 6.0723   5 2.7156 0.5511 2.178, 18.17 -0.16
BXD39 m 12.561 5.0834   3 2.9349 0.4047 8.254, 18.168 -0.01
BXD40 m 25.524 8.3117   4 4.1558 0.3256 15.594, 35.83 1.21
BXD43 m 2.4646 1.2537   7 0.47386 0.5087 1.11, 4.304 -0.96
BXD45 m 26.649 11.553   4 5.7763 0.4335 14.306, 41.694 1.32
BXD48 m 24.72 19.198   5 8.5858 0.7766 10.064, 58.39 1.14
BXD48a m 9.892 5.2249   4 2.6125 0.5282 3.68, 16.384 -0.26
BXD49 m 7.36 2.5421   5 1.1368 0.3454 4.63, 10.024 -0.5
BXD51 m 4.2444 3.1875   5 1.4255 0.751 0.856, 9.378 -0.8
BXD53 m 26.041 16.895   4 8.4477 0.6488 8.946, 49.18 1.26
BXD55 m 2.5268 0.42591   5 0.19047 0.1686 1.9, 2.932 -0.96
BXD6 m 0.355 0.08344   2   0.059 0.235 0.296, 0.414 -1.16
BXD62 m 3.8428 5.469   5 2.4458 1.4232 0.564, 13.502 -0.83
BXD63 m 7.905 2.1309   4 1.0654 0.2696 4.872, 9.472 -0.45
BXD64 m 10.648 4.659   5 2.0836 0.4375 4.712, 15.224 -0.19
BXD66 m 1.8536 1.006   5 0.4499 0.5427 0.768, 3.386 -1.02
BXD67 m 0.9595 0.48084   4 0.24042 0.5011 0.314, 1.378 -1.11
BXD69 m 18.232 7.9247   5 3.544 0.4347 7.304, 25.508 0.52
BXD73 m 25.692 18.361   4 9.1805 0.7146 9.496, 51.9 1.23
BXD75 m 51.25 63.32   5 28.319 1.2356 9.812, 161.8 3.64
BXD77 m 11.344 6.3119   5 2.8228 0.5564 5.588, 18.65 -0.13
BXD79 m 12.705 6.9249   5 3.0969 0.5451 7.0, 22.086 0.0
BXD8 m 10.52 8.6352   5 3.8618 0.8208 3.134, 23.59 -0.2
BXD81 m 28.862 32.352   3 18.678 1.1209 6.874, 66.01 1.53
BXD84 m 20.804 10.84   5 4.8479 0.5211 5.372, 35.25 0.77
BXD87 m 16.662 6.8754   5 3.0748 0.4126 9.316, 25.098 0.38
BXD89 m 9.553 7.1924   6 2.9363 0.7529 2.55, 21.64 -0.29
BXD90 m 12.226 6.9599   5 3.1126 0.5693 3.426, 20.57 -0.04
C57BL/6J m 6.9292 2.3681   5 1.059 0.3418 3.408, 9.588 -0.54
DBA/2J m 4.394 2.8702   4 1.4351 0.6532 1.692, 8.384 -0.78


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 3.45002 6.2968281824 15.909370371 -9.009330371
BXD100 m 5.5268 6.2968281824 17.986150371 -6.932550371
BXD11 m 2.9375 7.0400679293 16.8674771926 -10.9924771926
BXD12 m 15.0353333333 8.1291702282 31.1202854972 -1.0496188305
BXD27 m 7.4255 7.0400679293 21.3554771926 -6.5044771926
BXD32 m 14.2056 6.2968281824 26.664950371 1.746249629
BXD34 m 11.0188 6.2968281824 23.478150371 -1.440550371
BXD39 m 12.5606666667 8.1291702282 28.6456188305 -3.5242854972
BXD40 m 25.5245 7.0400679293 39.4544771926 11.5945228074
BXD43 m 2.4645714286 5.3217911297 12.9946444058 -8.0655015487
BXD45 m 26.6495 7.0400679293 40.5794771926 12.7195228074
BXD48 m 24.7204 6.2968281824 37.179750371 12.261049629
BXD48a m 9.892 7.0400679293 23.8219771926 -4.0379771926
BXD49 m 7.36 6.2968281824 19.819350371 -5.099350371
BXD51 m 4.2444 6.2968281824 16.703750371 -8.214950371
BXD53 m 26.0415 7.0400679293 39.9714771926 12.1115228074
BXD55 m 2.5268 6.2968281824 14.986150371 -9.932550371
BXD6 m 0.355 9.9561595456 20.0549626693 -19.3449626693
BXD62 m 3.8428 6.2968281824 16.302150371 -8.616550371
BXD63 m 7.905 7.0400679293 21.8349771926 -6.0249771926
BXD64 m 10.648 6.2968281824 23.107350371 -1.811350371
BXD66 m 1.8536 6.2968281824 14.312950371 -10.605750371
BXD67 m 0.9595 7.0400679293 14.8894771926 -12.9704771926
BXD69 m 18.2316 6.2968281824 30.690950371 5.772249629
BXD73 m 25.6925 7.0400679293 39.6224771926 11.7625228074
BXD75 m 51.2476 6.2968281824 63.706950371 38.788249629
BXD77 m 11.344 6.2968281824 23.803350371 -1.115350371
BXD79 m 12.7048 6.2968281824 25.164150371 0.245449629
BXD8 m 10.52 6.2968281824 22.979350371 -1.939350371
BXD81 m 28.8623333333 8.1291702282 44.9472854972 12.7773811695
BXD84 m 20.8036 6.2968281824 33.262950371 8.344249629
BXD87 m 16.662 6.2968281824 29.121350371 4.202649629
BXD89 m 9.553 5.7481913938 20.9267787501 -1.8207787501
BXD90 m 12.2256 6.2968281824 24.684950371 -0.233750371
C57BL/6J m 6.9292 6.2968281824 19.388550371 -5.530150371
DBA/2J m 4.394 7.0400679293 18.3239771926 -9.5359771926




  GWAS USING LINEAR MIXED MODELS